Iwan Sovani
Department Of Ophthalmology, Faculty Of Medicine, Padjadjaran University Cicendo National Eye Center, Bandung, West Java

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Prevalence and Associated Factors of Diabetic Retinopathy in People with Type 2 Diabetes Attending Community Based Diabetic Retinopathy Screening in Greater Bandung, Indonesia Halim, Aldiana; Syumarti, Syumarti; Rini, Mayang; Ratnaningsih, Nina; Iskandar, Erwin; Sovani, Iwan; Virgana, Rova; Dahlan, Muhammad Rinaldi
International Journal of Retina Vol 5 No 1 (2022): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2022.vol005.iss001.172

Abstract

Introduction: Determine the prevalence and associated factors of diabetic retinopathy (DR) among people with type 2 diabetes. Design: Cross-sectional study Methods: We obtained data of people with type 2 diabetes retrospectively from a community-based DR screening database in Greater Bandung, Indonesia. We encoded the two fields mydriatic 45-degree fundus images to estimate prevalence. The associated factors analysis used multivariate logistic regression. Results: We screened a total of 4,251 people with type 2 diabetes from January 2016 to December 2019. The overall age-standardised prevalence of any DR was 30.7% (95% CI: 28.7%-32.8%) and vision-threatening DR 7.6% (95% CI: 6.5%-9.0%). The following factors were associated with a higher prevalence of any DR: ages 50+ (OR:1.37; 95% CI:1.05-1.77), duration of diabetes five to ten years (OR:1.38; 95% CI:1.11-1.71) and more than ten years (OR:1.40; 95% CI:1.13-1.73), and postprandial blood glucose 200 mg/dl and higher (OR:1.27; 95% CI:1.03-1.52). The following factors were associated with a higher prevalence of vision-threatening DR: duration of diabetes five to ten years (OR:2.01; 95% CI:1.39-2.91) and more than ten years (OR:1.86; 95% CI:1.28-2.71), postprandial blood glucose 200 mg/dl or higher (OR:1.52; 95% CI:1.05-2.21) and systolic blood pressure 180 mmHg or higher (OR:2.67; 95% CI:1.16-6.17). Conclusion: Diabetic retinopathy is prevalent among people with type 2 diabetes. People with diabetes should regulate their blood glucose and blood pressure to prevent retinopathy related vision loss.
Manifestasi Okular dan Non Okular Sindrom Rubella Kongenital Pada Penderita Katarak Kongenital Irma, Josiah; Sovani, Iwan; Wahyu, Maya Sari; Karfiati, Feti
Medicinus Vol. 6 No. 3 (2017): June 2017 - September 2017
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v6i3.1148

Abstract

Background: Maternal infection with rubella in the first trimester of pregnancy result in congenital rubella syndrome (CRS). It caused blindness, deafness, congenital heart dissease and mental retardation. One of the main cause of blindness in CRS is congenital cataract. Infant affected with CRS worldwide estimated 238.000 each year and 46.000 live in South East Asia.Objective: This study aimed to looked for other ocular and non ocular manifestation from 0-11months old congenital cataract infants based on World Health Organization (WHO) CRS case definiton: suspected, clinically confirmed and labaratory confirmed.Methods:This is a retrospective observational study. We colected all data from computer base medical record, patient with congenital cataract 0-11 months old that came to Pediatric Ophthalmology unit Cicendo Eye Hospital from January 2012 until December 2013. Age, sex, laterality, axial length, cataract morphology, retinopathy pigmentary, cardiac dissorder, hearing impairment, mental dissorder and laboratory serology rubella for IgM and IgG were recorded.Results: We found ninety three patients diagnosed with CRS from congenital cataract cases. Ocular manifestation include microphthalmia in 63 eyes (33.9%), microcornea in 30 eyes (16.1%), and pigmentary retinopathy in 1 eye (0.5%) . The most common type of cataract morphology was nuclear type (49.9%.). Non-ocular manifestation include cardiac dissorder in 16 cases (17.2%), hearing impairment in 1 case (1.1%) and mental retardation in 6 cases (6.4%). Case definition based on WHO criteria were 93 cases (100%) for suspected, 20 cases (25.8%) for clinically confirmed and 15 cases (42,8%) for laboratory confirmed.Conclusion: Ocular manifestation for CRS in congenital cataract 0-11 months old were microphthalmia, microcornea, pigmentary retinopathy. Other manifestation found were cardiac disorder, hearing impairment and mental retardation.