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All Journal Indonesian Journal of Chemistry Jurnal Pengabdian Masyarakat Bangsa
Nurroudhlotiningtyas, Tejayani
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Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Edukasi Penggolongan dan Tata Cara Dapatkan Gunakan Simpan Buang (DAGUSIBU) Obat di Stadion Manahan Kota Surakarta Hadi, Saptono; Astuti, Rini Budi; Rahma, Syafa Muthi’atur; Nurroudhlotiningtyas, Tejayani; Dinanti, Adityas Arum; Anggoro, Arya; Fitria, Anisa; Annafis, Hasna Ulya; Siadari, Kristy Linosi; Kurnia, Raihan Daffa; Ramadhani, Salma Aqilah
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 5 (2025): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i5.2496

Abstract

Pengabdian masyarakat ini dilakukan sebagai upaya untuk meningkatkan pengetahuan terkait DAGUSIBU obat kepada masyarakat yang sedang berada di Stadion Manahan, Kecamatan Banjarsari, Kota Surakarta, Jawa Tengah. Pemberian edukasi dilakukan dalam bentuk pemberian edukasi, pemberian leaflet, pengisian kuesioner pemahaman, dan pemberian gift kecil berupa vitamin C pada akhir sesi edukasi. Edukasi berupa leaflet dan penyampaian materi secara langsung meningkatkan pengetahuan masyarakat mengenai DAGUSIBU obat. Terdapat rata-rata 86,4% responden dapat menjawab kuisioner dengan benar.
The Effect of pH on Quercetin Release from Zn Crosslinked Chitosan-Alginate Membrane and Its Kinetics Hastuti, Budi; Nurroudhlotiningtyas, Tejayani; Hadi, Saptono; Martanisa, Mutiah
Indonesian Journal of Chemistry Vol 26, No 1 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104072

Abstract

This research aims to assess the ability of Zn-crosslinked chitosan (Chi) and alginate (AG) membranes to deliver quercetin into the body by testing the release with variations in the pH of the dissolution medium. Chi-AG membrane crosslinked with Zn and loaded with quercetin to produce Chi-AG-Zn membrane with tear-resistant and elastic properties. The FTIR spectrum of the Zn crosslinked Chi-AG membrane containing quercetin shows the formation of a Chi-AG-Zn membrane with a shift in the characteristic peaks and the formation of new characteristic groups, namely Zn at a wavelength of 549 cm−1 and phenol at 1379 cm−1. SEM testing showed that the surface of the fibrous membrane and quercetin were successfully loaded. Entrapment efficiency testing yielded relatively high results, specifically 91 ± 0.08%. The release of quercetin from the Zn-crosslinked Chi-AG membrane was investigated by varying the pH of the dissolution medium, specifically at pH 1.2, 5.0, and 7.4. The results showed the highest release at pH 7.4. Membrane release follows the Korsmeyer-Peppas model, and the release mechanism is governed by Fick's diffusion. These findings suggest that the Zn-crosslinked Chi-AG membrane has potential as a pH-responsive drug delivery system for targeted release in intestinal conditions.
Co-Authors Abda Abda Anggoro, Arya Annafis, Hasna Ulya Astuti, Rini Budi Budi Hastuti Dinanti, Adityas Arum Kurnia, Raihan Daffa Martanisa, Mutiah Rahma, Syafa Muthi’atur Ramadhani, Salma Aqilah Saptono Hadi, Saptono Siadari, Kristy Linosi