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All Journal JMM (Jurnal Masyarakat Mandiri) Medika Kartika : Jurnal Kedokteran dan Kesehatan
Widyasari, Aliya Syukur
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Dentistry Health Professions Medicine & Pharmacology Veterinary Other

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PELATIHAN PENGOLAHAN SAYUR OKRA UNTUK TERAPI ADJUVANT PENYAKIT DIABETES MELLITUS PADA KELOMPOK PKK Safitri, Azizah Hikma; Widyasari, Aliya Syukur; Sayyida, Rahmata Almas; Tyagita, Nurina
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 3 (2025): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i3.30547

Abstract

Abstrak: Diabetes mellitus merupakan salah satu penyakit metabolik dengan prevalensi tinggi di Indonesia. Prinsip tatalaksana diabetes mellitus melalui pengontrolan kadar glukosa darah dapat dilakukan dengan penambahan okra dengan kandungan senyawa aktif sebagai terapi adjuvant diabetes mellitus. Pelatihan bertujuan untuk meningkatkan pengetahuan dan kemampuan masyarakat terkait cara pengolahan okra sebagai terapi adjuvant diabetes melitus. Metode: Ceramah, pelatihan, dan pendampingan dilakukan pada kegiatan ini. Evaluasi keberhasilan kegiatan dilakukan melalui one group pre and post-test dengan peserta 25 kader PKK Desa Banjardowo, Kota Semarang. Peserta diberikan lembar pertanyaan sebelum dan sesudah edukasi kesehatan dan pelatihan pengolahan okra. Hasil jawaban benar pre dan post-test dianalisis dan ditemukan perbedaan yang signifikan pada rerata jumlah jawaban benar pre-test dan post-test. Kegiatan edukasi dan pelatihan terkait pengolahan okra dapat meningkatkan pengetahuan dan kemampuan peserta hingga 26,4% dari pengetahuan awal saat pre-test melalui peningkatan jumlah jawaban benar pada sesi post-test setelah diberikan intervensi berupa edukasi dan pelatihan pengolahan okra sebagai terapi adjuvant DM. Abstract: Diabetes mellitus is one of the metabolic diseases with high prevalence in Indonesia. The principle of diabetes mellitus management through controlling blood glucose levels can be done by adding okra with active compound content as adjuvant therapy for diabetes mellitus. This training aimed to evaluate the impact of education on enhancing community knowledge and skills in processing okra as an adjuvant therapy for diabetes mellitus. Method: Lectures, training, and mentoring were conducted in this activity. Evaluation was conducted through one group pre and post-test with 25 PKK cadres from Banjardowo Village, Semarang City. Participants were given a questionnaire before and after health education and okra processing training. The results of the correct answers to the pre and post-test were analyzed and a significant difference was found in the average number of correct answers to the pre-test and post-test. The education and training activities improved participants’ knowledge and skills by 26.4% from baseline, as evidenced by the increased number of correct responses in the post-test following the intervention. Conclusion: Education and training on okra processing significantly enhanced participants’ understanding and ability to utilize okra as an adjuvant therapy for diabetes mellitus.
THE EFFECT OF CURCUMA ZEDOARIA EXTRACT ON LIVER DAMAGE BIOMARKERS IN A DIABETIC RAT MODEL Maulia, Nurdiana; Amalia, Gradis; Azizah, Muna Dasa; Widyasari, Aliya Syukur; Ramadhani, Hesa Haidar; Pramesti, Marshanda Hasna; Sampurna, Sampurna; Tyagita, Nurina; Widiyanto, Bagas
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 9 No 1 (2026): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Abstract

Uncontrolled hyperglycemia in diabetes mellitus (DM) can cause liver tissue damage. This can be characterized by increased levels of several biomarkers, including transaminase and transferase enzymes and alpha-fetoprotein (AFP) level, as well as decreased bilirubin and albumin levels. White turmeric (Curcuma zedoaria) contains high levels of antioxidants and anti-inflammatory compounds. The objective of this study was to determine the effect of white turmeric extract on liver damage biomarkers in DM rats. This true experimental study used a post-test-only control group design. The test subjects were 28 male Wistar rats divided through two randomizations. In the first randomization, rats were allocated into two groups (control/K1 and the DM rat group) with a ratio of 1:3. DM was induced by an intraperitoneal injection of niacinamide (NA) 45 mg/kg BW followed by streptozotocin (STZ) 110 mg/kg BW 15 minutes later. The second randomization divided the DM rats into three groups: K2 (DM only), K3, and K4 (each receiving white turmeric extract at 9 and 18 mg/g BW, respectively) for 28 days. The next day, liver biomarkers were measured. A one-way ANOVA test for SGOT, GGT, AFP, and albumin levels showed p<0.05. Likewise, the Kruskal-Wallis test for SGPT and bilirubin levels also showed significant differences. The levels of SGOT, SGPT, GGT, AFP, bilirubin, and albumin differed significantly among the four groups. AFP and bilirubin levels in K4 were lower than in K3 and K2, while albumin levels were higher than in those groups. Administration of white turmeric extract reduced transaminase and transferase enzymes, bilirubin, and AFP, and increased albumin levels in DM Wistar rats. Keywords: diabetes mellitus, liver damage biomarkers, white turmeric DOI : 10.35990/mk.v9n1.p1-12
Co-Authors Amalia, Gradis Azizah Hikma Safitri Azizah, Muna Dasa Bagas Widiyanto, Bagas Maulia, Nurdiana Pramesti, Marshanda Hasna Ramadhani, Hesa Haidar Sampurna Sampurna, Sampurna Sayyida, Rahmata Almas Tyagita, Nurina