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All Journal Science and Technology Indonesia Lontara Journal Of Health Science And Technology
Anasiru, Rayhan Firman
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Physics

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Evaluasi Terapi Pada Pasien Gastroenteritis Dengan Abdomen Akut Lamalani, Alia Nur; Abdulkadir, Widy Susanti; Yusuf, Annisa Humaira; Hippy, Fajria Indah; Monoarfa, Magfira Susilowati; Anasiru, Rayhan Firman; Lakoro, Siti Ruqaiyah
Lontara Journal of Health Science and Technology Vol. 6 No. 2 (2025): Juli-Desember 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v6i2.579

Abstract

Gastroenteritis is one of the major health problems that is still often found in developing countries, especially in vulnerable groups. This study aims to evaluate pharmacological and non-pharmacological therapy in a 43-year-old female patient diagnosed with gastroenteritis due to infection and accompanied by acute abdomen. This study used a case study approach with the SOAP method, based on medical record data at Tombulilato Hospital, Gorontalo. Initial therapy included rehydration using Ringer Lactate, and administration of Omeprazole, Ondansetron, and Ceftriaxone. Therapy was continued with symptomatic drugs such as Paracetamol, Ketoprofen, and Sucralfate. Daily evaluation showed significant clinical improvement, and the patient was discharged on the fourth day in stable condition after therapy was switched to oral form. This study shows the importance of choosing the right therapy, monitoring patient conditions, and patient education in accelerating recovery. It is recommended to replace Omeprazole with Esomeprazole and Ketoprofen with a combination of Paracetamol-Tramadol to reduce the risk of gastrointestinal side effects.
Biopotential of Gorontalo Hulu’u Fish (Giuris margaritacea) Albumin in a Novel Spray Gel Formulation for the Treatment of BurnWounds: In Vivo Evaluation in Rats Paneo, Mohamad Aprianto; Djuwarno, Endah Nurrohwinta; Habibie, Sitty Ainsyah; Thomas, Nurain; Latif, Multiani S.; Munafri, Nur Alifia Karina; Anasiru, Rayhan Firman
Science and Technology Indonesia Vol. 11 No. 2 (2026): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.2.389-404

Abstract

This study aimed to evaluate the efficacy of different concentrations of Hulu’u fish albumin-based spray gels in promoting wound healing in burn injuries in male white rats. The formulations included 10%, 15%, and 20% concentrations of Hulu’u fish albumin, which were compared to a commercial snakehead fish albumin gel (positive control) and a spray gel base without albumin (negative control). Wound diameter reduction was assessed over seven days. The results indicated a clear dose response relationship, with the 20% Hulu’u fish albumin formulation (F3) achieving the most significant reduction in wound diameter, averaging 1.57 mm (range: 1.5–1.6 mm), representing a 91.8% improvement compared to the negative control group, which showed an average reduction of 19.13 mm (range: 18.1–19.7 mm). The Positive Control (snakehead fish albumin gel) demonstrated a moderate reduction with an average of 6.97 mm (range: 6.6–7.6 mm). The 10% Hulu’u fish albumin (F1) and 15% Hulu’u fish albumin (F2) formulations showed moderate improvements, with average reductions of 4.73 mm (range: 4.4–5.1 mm) and 4.5 mm (range: 4.7–3.9 mm), respectively. These findings suggest that higher concentrations of Hulu’u fish albumin, particularly the 20% formulation, offer superior wound healing properties, outperforming both the negative control and the commercial snakehead fish albumin gel. The study highlights the potential of Hulu’u fish albumin as a novel bioactive compound for burn wound treatment and warrants further investigation for clinical applications.
Co-Authors Endah Nurrohwinta Djuwarno Hippy, Fajria Indah Lakoro, Siti Ruqaiyah Lamalani, Alia Nur Latif, Multiani S. Mohamad Aprianto Paneo Monoarfa, Magfira Susilowati Munafri, Nur Alifia Karina Nur Ain Thomas Sitty Ainsyah Habibie Widy Susanti Abdulkadir Yusuf, Annisa Humaira