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All Journal Indonesian Journal of Global Health research JUKEJ: Jurnal Kesehatan Jompa
Lubis, Mohammad Riza
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Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary

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Neutrophil-To-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) as Predictors of Mortality in Chronic Kidney Disease Patients Undergoing Hemodialysis Silaban, Roy Efendi; Arto, Nindia Sugih; Lubis, Mohammad Riza
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6998

Abstract

Chronic Kidney Disease (CKD) is associated with high mortality, especially among patients undergoing hemodialysis (HD). Inflammation markers such as the Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) have been linked to mortality prediction. This study aims to evaluate the role of NLR and PLR as mortality predictors in CKD patients undergoing HD at H. Adam Malik Hospital, Medan. This retrospective study analyzed CKD patients receiving HD from January to December 2023, aged 18-60 years, and undergoing routine HD for at least 3 months. Excluded were those with comorbidities, immunosuppressant use, or incomplete records. Data on demographics, laboratory values (including NLR and PLR), and mortality outcomes were collected. ROC curve and logistic regression analysis were used. Out of 108 patients, 35 (32.4%) died. The median NLR was significantly higher in the mortality group (7.89 vs. 3.41, p < 0.001), while PLR showed no significant difference. ROC analysis revealed NLR's moderate accuracy (AUC = 73.3%, cut-off = 5). Multivariate analysis identified coronary artery disease history, age, and creatinine levels as significant mortality factors. NLR is a moderate predictor of mortality in CKD patients undergoing HD, while PLR is not.
Hubungan Red Cell Distribution Width Terhadap Kadar Feritin dan Total Iron Binding Capacity Pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Purnamasari, Yeni; Adhayanti, Ida; Tarigan, Radar Radius; Lubis, Mohammad Riza; Arto, Nindia Sugih; Youvella, Sylvia
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 3 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss3.1995

Abstract

Tujuan penelitian untuk mengetahui hubungan RDW terhadap hasil TIBC dan kadar feritin pada pasien penyakit ginjal kronik yang menjalani hemodialisis di RS Adam Malik. Metode penelitian merupakan studi retrospektif, yang melibatkan 114 pasien PGK yang menjalani hemodialisis di RS Adam Malik pada tahun 2023. Pasien yang terlibat pada studi ini yakni pasien berusia ≥ 18 tahun, menjalani hemodialisis rawat jalan, dan memiliki data rekam medis yang lengkap. Data yang telah terkumpul selanjutnya dianalisis menggunakan uji korelasi Spearman. Hasil penelitian menunjukan mayoritas pasien berjenis kelamin laki-laki (62,3%), berusia 46–60 tahun (43,0%), lama hemodialisis < 5 tahun (70,2%), dan menderita diabetes (56,1%). Sebagian besar memiliki RDW normal (60,5%), feritin tinggi (78,1%), dan TIBC rendah (69,3%), menunjukkan adanya inflamasi kronik dan kelebihan besi. Tidak terdapat hubungan signifikan antara RDW dengan TIBC maupun feritin, sehingga RDW tidak mencerminkan status besi atau inflamasi pada pasien hemodialisis. Kesimpulannya tidak ada hubungan antara RDW terhadap TIBC dan feritin.
Co-Authors Adhayanti, Ida Nindia Sugih Arto, Nindia Sugih Silaban, Roy Efendi Tarigan, Radar Radius Yeni Purnamasari, Yeni Youvella, Sylvia