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DETERMINANTS AFFECTING THE DEPRESSION OF INFARCTION POST STROKE PATIENTS IN (SAIFUL ANWAR HOSPITAL MALANG) Munir, Badrul; Nasution, Arief Alamsyah; Purnamasari, Yeni
Malang Neurology Journal Vol 2, No 2 (2016): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.464 KB) | DOI: 10.21776/ub.mnj.2016.002.02.3

Abstract

Background. Stroke is a functional disorder of the brain that occurs suddenly with signs and symptoms of both focal and global clinical lasting more than 24 hours, or can lead to death due to circulatory disorders of the brain. Stroke ranks third leading cause of death in Indonesia. Someone with stroke will leading mood disruption that would cause a depression. Objective. To determine the effect on depression of stroke infarction.Methods. The study used descriptive analytic cross-sectional study. 42 samples was selected by consecutive method. The distribution of the sample are 18 males and 24 females, 23 samples below 60 years and 19 samples over 60 years, 13 samples had duration of suffering a stroke less than 6 months and 29 samples above 6 months. The independent variables in this study were age, sex, and duration of suffering a stroke, while the depression is the dependent variable. Depression was assessed using the Hamilton Depression Rating Scale (HDRS). Results. The results used logistic regression test obtained value of (p = 0.021) is significant in age.Conclusion. The age is the determinant affecting the quality of life after stroke infarction.
ANALISIS PENGARUH INSTRUMEN PEMBAYARAN NON-TUNAI TERHADAP STABILITAS SISTEM KEUANGAN DI INDONESIA Lintangsari, Nastiti Ninda; Hidayati, Nisaulfathona; Purnamasari, Yeni; Carolina, Hilda; Ramadhan, Wiangga Febranto
JURNAL DINAMIKA EKONOMI PEMBANGUNAN Vol 1, No 1 (2018): April
Publisher : Fakultas Ekonomika dan Bisnis, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (804.088 KB) | DOI: 10.14710/jdep.1.1.47-62

Abstract

The payment system is an important component in the economy especially to ensure the implementation of payment transactions made by the public and the business world. In addition, the payment system also plays an important role in supporting financial system stability and implementation of monetary policy. Along with rapid technological developments, patterns and payment systems in economic transactions are constantly changing. Technological advances in the payment instruments shift the role of cash as a means of payment in the form of more efficient and economical non-cash payments. Non-cash payment instruments used in this study are card-based payment instruments (APMK) and electronic money (e-money). The aim of this study is to examine the effect of non-cash payment instruments development on money supply (M1), velocity of money, inflation, interest rate, and financial system stability. A set of secondary data are assessed through official website of Bank Indonesia from year 2009-2017. Multiple regression analysis are employed to elaborate the results. The result showed that e-money and credit card transactions have a significant positive effect on M1, e-money transactions have a significant negative effect on interest rates, and credit card transactions have a significant positive effect on interest rates.
DETERMINAN PROFITABILITAS BANK UMUM DI INDONESIA (Studi Kasus: Bank Kategori BUKU 4) Purnamasari, Yeni
JURNAL DINAMIKA EKONOMI PEMBANGUNAN Vol 2, No 1 (2019): April
Publisher : Fakultas Ekonomika dan Bisnis, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (929.38 KB) | DOI: 10.14710/jdep.2.1.1-14

Abstract

This study aims to analyze the determinant of banking profitability, which is influenced by internal factors and external factors. This study focus on the impact of internal factors (CAR, NPL, and LDR) and external factors (BI rate and money supply) on bank profitability which is proxied by Return on Assets (ROA). The sample used bank category BUKU 4, with period from 2008 to 2017. The method used in this study is Fixed Effect Method (FEM). The empirical result shows that internal factors (NPL and LDR) have a significant effect on ROA, while CAR had no significant effect on ROA. External factors, BI rate and money supply also have a significant effect on ROA.
Perindopril decreases angiotensin-converting enzyme 2 (ACE2) expression in human adipocytes exposed to SARS-CoV-2 S1 spike protein Harsoyo, Primasitha M.; Ardiana, Meity; Hermawan, Hanestya O.; Purnamasari, Yeni; Anandita, Faizal A.
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.746

Abstract

The expression of angiotensin-converting enzyme 2 (ACE2) in the adipose tissues of obese patients needs further study, as it may aid infection and serve as a viral reservoir. There has been controversy over whether to use ACE inhibitors to prevent coronavirus disease 2019 (COVID-19) severity. Perindopril, an ACE2 inhibitor, has been proposed; however, its relationship with COVID-19 has not yet been clear. The aim of this study was to investigate the effect of perindopril to reduce the expression of ACE2 and pro-inflammatory cytokine in adipocytes exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Enzymatic isolation of adipose tissues was performed from obese male donor patients aged 30–50 years, then exposed it with SARS-CoV-2 S1 spike protein. This study also included human recombinant ACE2 (hrsACE2) as a comparison to perindopril. The expression of ACE2 was evaluated using ELISA. Our data indicated that SARS-CoV-2 Spike protein exposure increased ACE2 expression significantly. Administration of perindopril decreased ACE2 expression (43.37 µg/mL) significantly compared to the positive group (80.31 µg/mL) (p<0.001). Perindopril administration also decreased IL-6 levels significantly compared to positive group(p<0.001).  This study highlights that perindopril could reduce the ACE2 expression and pro-inflammatory cytokine levels in adipocytes exposed to SARS-CoV-2 S1 spike protein.
Aplikasi Teori Betty Neuman dalam Asuhan Keperawatan pada Kasus Luka Dekubitus dengan Hemiparese Pasca Stroke Purnamasari, Yeni; Nursanti, Irna
Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 1 (2024): Jurnal Sains, Teknologi dan Kesehatan, Januari 2024
Publisher : LPPM Institut Teknologi Dan Kesehatan Aspirasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/saintekes.v3i1.299

Abstract

The Neuman Theory emphasizes a holistic system view of individuals, regarding them as systems interacting with their environment. In the context of patients with hemiparesis and decubitus ulcers, the concept of internal and external stressors is applied to identify factors affecting health. This approach enables nurses to provide comprehensive care, focusing on the overall recovery of the patient.
Hubungan Red Cell Distribution Width Terhadap Kadar Feritin dan Total Iron Binding Capacity Pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Purnamasari, Yeni; Adhayanti, Ida; Tarigan, Radar Radius; Lubis, Mohammad Riza; Arto, Nindia Sugih; Youvella, Sylvia
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 3 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss3.1995

Abstract

Tujuan penelitian untuk mengetahui hubungan RDW terhadap hasil TIBC dan kadar feritin pada pasien penyakit ginjal kronik yang menjalani hemodialisis di RS Adam Malik. Metode penelitian merupakan studi retrospektif, yang melibatkan 114 pasien PGK yang menjalani hemodialisis di RS Adam Malik pada tahun 2023. Pasien yang terlibat pada studi ini yakni pasien berusia ≥ 18 tahun, menjalani hemodialisis rawat jalan, dan memiliki data rekam medis yang lengkap. Data yang telah terkumpul selanjutnya dianalisis menggunakan uji korelasi Spearman. Hasil penelitian menunjukan mayoritas pasien berjenis kelamin laki-laki (62,3%), berusia 46–60 tahun (43,0%), lama hemodialisis < 5 tahun (70,2%), dan menderita diabetes (56,1%). Sebagian besar memiliki RDW normal (60,5%), feritin tinggi (78,1%), dan TIBC rendah (69,3%), menunjukkan adanya inflamasi kronik dan kelebihan besi. Tidak terdapat hubungan signifikan antara RDW dengan TIBC maupun feritin, sehingga RDW tidak mencerminkan status besi atau inflamasi pada pasien hemodialisis. Kesimpulannya tidak ada hubungan antara RDW terhadap TIBC dan feritin.
Effect of Light, Medium, and Dark Roasting on Antioxidant Activity of Gununghalu Arabica Coffee (Coffea arabica L.) Rahmawati, Irma; Purnamasari, Yeni
International Journal of Business, Economics, and Social Development Vol. 5 No. 1 (2024)
Publisher : Rescollacom (Research Collaborations Community)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46336/ijbesd.v5i1.586

Abstract

Coffee is one of the popular drinks for Indonesian people. Coffee consumption in Indonesia has increased very rapidly. The influence of lifestyle and the increasing number of cafes and coffee shops contribute to the increase in coffee consumers. One downstream processing of coffee beans is roasting coffee beans, which consists of light, medium, and dark roasting. This study aimed to determine the antioxidant activity of Gununghalu Arabica Coffee (Coffea arabica L.) with Light Roasting, Medium Roasting, and Dark Roasting Techniques. This research is an experimental study, where the antioxidant activity analysis was carried out using the DPPH method (2,2-diphenyl-1-picrylhydrazyl). Gununghalu Arabica coffee with light, medium, and dark roasting techniques positively containing flavonoids, alkaloids, saponins, tannins, and terpenoids. The results showed that the IC50 value of Gununghalu Arabica coffee for light, medium, and dark roasting was 102.94 ppm, 70.66 ppm, and 87.66 ppm. The test results show that the antioxidant activity of Gununghalu Arabica coffee with light roasting techniques are moderate, while medium and dark roasting techniques are strong. The results of this study are expected to provide implications for the development of coffee processing techniques to have maximum health benefits.