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All Journal Jurnal Buana Farma JURNAL KESEHATAN YAMASI MAKASSAR
Pratama, Andri Anugrah
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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AKTIVITAS TABIR SURYA EKSTRAK ETANOL DAUN Acacia auriculiformis ASAL KOLAKA MENGGUNAKAN SPEKTROFOMETRI UV-Vis Ardiansyah, Akhmad; Duppa, Muhammad Taufik; Masri, Anshari; Pratama, Andri Anugrah
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.401

Abstract

Excessive exposure to UV radiation can cause skin damage. Preventive measures can be taken by using sunscreen. Acacia auriculiformis is a species from the Fabaceae family, many of which are known for their antioxidant activity. Acacia auriculiformis can act as a natural sunscreen because it contains secondary metabolite compounds with conjugated double bond structures, which are known to reduce the intensity of UV exposure on the skin by absorbing ultraviolet radiation. This study aimed to identify the secondary metabolites in the ethanol extract of Acacia auriculiformis leaves from Kolaka and to determine its Sun Protection Factor (SPF) value using UV-Vis spectrophotometry. The extraction of Acacia auriculiformis leaves was carried out using the maceration method with 70% ethanol as the solvent. The sunscreen activity was determined based on the SPF values. The SPF values of the extract at concentrations of 50 ppm, 100 ppm, 150 ppm, and 200 ppm were 3.8712 (minimal protection), 6.4880 (extra protection), 9.5359 (maximum protection), and 12.5816 (maximum protection), respectively. The results indicate that sunscreen activity increases in proportion to the extract concentration. Acacia auriculiformis leaves have the potential to be developed as a sunscreen formulation.
FORMULASI SIRUP DEKOKTA KERANG TUDE BOMBANG (Atactodea striata) SEBAGAI HEPATOPROTEKTOR ALAMI Ashar, Muhammad; Pratiwi, Ines Septiani; Pratama, Andri Anugrah; Feriadi, Eva
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1477

Abstract

The Tude Bombang clam (Atactodea striata) is a potential hepatoprotective agent due to its bioactive protein content and low fat levels, which contribute to liver protection through antioxidant activity, hepatocellular repair, and prevention of lipid accumulation in liver cells. This study aimed to formulate a decoction syrup of Tude Bombang clam and evaluate its hepatoprotective effects against paracetamol-induced hepatotoxicity in mice, as well as assess its organoleptic properties, homogeneity, and pH. The results showed that SGOT and SGPT levels in the normal control group remained stable (SGOT: 17.7–17.2 U/L; SGPT: 7.5–7.2 U/L), whereas the negative control group exhibited persistent elevations (SGOT: 374.7–373 U/L; SGPT: 97.2–95.6 U/L), confirming liver damage. The positive control (curcumin) reduced SGOT to 220.3 U/L and SGPT to 102.4 U/L. The Tude Bombang clam syrup demonstrated dose-dependent hepatoprotective effects, with the 60% concentration producing the most significant reductions in SGOT (350.9 to 288.9 U/L) and SGPT (96 to 73.6 U/L), indicating its ability to stabilize liver enzymes and mitigate hepatocellular injury. Organoleptic evaluation revealed acceptable sensory characteristics, homogeneity testing confirmed uniform dispersion without sedimentation, and the pH values (7.02–7.20) fell within the neutral range recommended for oral syrups. Overall, the Tude Bombang clam syrup exhibited favorable physical properties and hepatoprotective potential through its bioactive protein content and low fat levels, making it a promising candidate for functional hepatoprotective formulations.
Co-Authors Ardiansyah, Akhmad Ashar, Muhammad Duppa, Muhammad Taufik Eva Feriadi Masri, Anshari Pratiwi, Ines Septiani