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All Journal Medali Jurnal : Media Dental Intelektual Journal of Dental and Biosciences
Bagus, Zahran Uzla Attaqi
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Dentistry Health Professions Medicine & Pharmacology Public Health

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Antifungal Activity Test Ethanol Extract Of Awar-Awar Leaves (Ficus septica Burm. F.) to Candida tropicalis As The Cause of Oral Candidiasis In Vitro Bagus, Zahran Uzla Attaqi; Anjarwati, Dwi Utami; Djati, Fanni Kusuma; Ichsyani, Meylida
Jurnal Medali Vol 7, No 2 (2025): Media Dental Intelektual Agustus 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.7.2.136-144

Abstract

Background: Oral candidiasis is an infection in the oral cavity caused by Candida tropicalis, a non-Candida albicans (NCAC) species with the highest virulence. The first-line treatment for oral candidiasis is nystatin; however, it may cause side effects. One alternative treatment for oral candidiasis is the use of Ficus septica Burm. F. leaves, which contain active compounds such as saponins, tannins, flavonoids, and triterpenoids, all of which have potential antifungal properties. This study aims to evaluate the antifungal activity ethanol extract of awar-awar leaves to Candida tropicalis as the cause of Oral Candidiasis in vitro. Method: This experimental laboratory study used a posttest-only control group design, comparing the treatment groups with ethanol extract of Ficus septica burm. F leaves at concentrations of 4%, 8%, 16%, and 32% with a positive control group (nystatin) and a negative control group (Dimethyl sulfoxide). Antifungal activity was tested using the microdilution broth method to determine the Minimum Inhibitory Concentration (MIC) and the spread plate method to determine the Minimum Bactericidal Concentration (MBC). Colony growth of C. tropicalis was measured using the Total Plate Count (TPC) method, followed by calculating the inhibition percentage. Result: The analysis of this study showed that the MIC of Ficus septica Burm F leaf extract was at a concentration of 32%, and the MBC of the extract was also at a concentration of 32%, with a 100% inhibition percentage. Significant differences (p ≤ 0.05) were found between the concentrations of the ethanol extract of Ficus septica leaves.Conclussion: The conclusion of this study is that the ethanol extract of Ficus septica Burm. F leaves has antifungal activity in inhibiting the growth of C. tropicalis, the cause of oral candidiasis, with the most effective concentration being 32% with 100% inhibition.
Aktivitas Pemeliharaan Kesehatan Gigi dan Mulut serta Risiko Trauma Dental pada Penderes Nira Kelapa di Desa Sokawera, Kabupaten Banyumas Sari, Aniis Rakhmah; Bagus, Zahran Uzla Attaqi; Firdaus, Ananda Nurul; Izzati, Salsabila Dzil; Rosyadah, Nada Janardita; Setyaliani, Razin Alifahrezy; Nurcahyo, Ferdhana; Vida, Mary; Hidayah, Riski Amalia; Oktadewi, Fitri Diah
Journal of Dental and Biosciences Vol 3 No 01 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.01.11108

Abstract

Latar Belakang: Pekerjaan sebagai penderes nira kelapa masih banyak dijalani masyarakat Desa Sokawera akibat keterbatasan keahlian dan keterampilan di bidang pekerjaan lain. Aktivitas menderes nira menuntut kerja fisik yang tinggi serta paparan lingkungan yang berpotensi memengaruhi kondisi kesehatan gigi dan mulut, termasuk risiko terjadinya trauma dental akibat kecelakaan kerja. Penelitian ini bertujuan untuk menggambarkan aktivitas pemeliharaan kesehatan gigi dan mulut, upaya pengobatan mandiri atau tradisional saat mengalami keluhan sakit gigi, serta potensi risiko trauma dental pada penderes nira kelapa di Desa Sokawera. Metode: Penelitian ini menggunakan metode kualitatif dengan subjek sebanyak enam penderes nira kelapa di Desa Sokawera, Kecamatan Cilongok, Kabupaten Banyumas, berusia antara 19 hingga 61 tahun. Pengumpulan data dilakukan melalui wawancara semi terstruktur, observasi partisipan, dan dokumentasi. Hasil: Hasil penelitian menunjukkan adanya variasi perilaku dalam pemeliharaan kesehatan gigi dan mulut serta perbedaan cara pengobatan mandiri yang dilakukan oleh penderes nira. Sebagian besar responden menyatakan tidak mengonsumsi gula secara berlebihan, sementara dua responden mengonsumsi gula nira hanya sebagai campuran makanan. Selain itu, tidak ditemukan adanya kasus trauma dental pada subjek penelitian selama periode pengamatan. Kesimpulan: Penderes nira kelapa memiliki risiko pekerjaan yang tinggi, praktik pemeliharaan kesehatan gigi dan mulut yang dilakukan relatif beragam, dan tidak ditemukan kejadian trauma dental pada responden yang diteliti. Kata kunci: Kesehatan gigi dan mulut, trauma dental, penderes nira, pengobatan gigi dan mulut
Co-Authors Dwi Utami Anjarwati Fanni Kusuma Djati Firdaus, Ananda Nurul Fitri Diah Oktadewi Izzati, Salsabila Dzil Meylida Ichsyani Nurcahyo, Ferdhana Riski Amalia Hidayah Rosyadah, Nada Janardita Sari, Aniis Rakhmah Setyaliani, Razin Alifahrezy Vida, Mary