Upi Chairun Nisa
Department Of Biology, Faculty Of Mathematics And Natural Sciences, Universitas Indonesia, UI Campus Depok, 16424

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Zooremediation: Utilizing Animals for Environmental Purification and Pollution Mitigation Aini, Fadita Nurul; Nisa, Upi Chairun; Handayani, Windri; Maryenti, Tety; Yasman, Yasman
BIOEDUSCIENCE Vol 9 No 2 (2025): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18376

Abstract

Background: The global human population continues to grow rapidly, leading to increasing urban waste and environmental contamination. One emerging and promising approach to mitigating this pollution is zooremediation, which utilizes animals as biological agents for environmental cleanup. This review aims to critically assess the effectiveness of various animal species in removing specific classes of pollutants, with particular attention to their mechanisms of action—zooextraction, zootransformation, and zooaccumulation—and the environmental conditions under which they operate. Effectiveness is evaluated based on pollutant removal efficiency, adaptability to contaminated environments, and ecological safety. Methods: Through systematic literature analysis, we identified key species, including Geukensia demissa, Daphnia magna, and Anadara granosa, which demonstrated measurable success in the remediation of aquatic environments contaminated with heavy metals and organic pollutants. Additionally, soil-dwelling nematodes such as Caenorhabditis elegans and Cephalobus persegnis play critical roles in hydrocarbon degradation and in enhancing microbial synergy in polluted substrates. These findings highlight the diverse functional capacities of animals in bioremediation efforts. The methodology employed in this study is a comprehensive literature review, focusing on peer-reviewed articles published over the last two decades. Results: This review synthesizes findings related to pollutant types, animal species used in zooremediation, remediation outcomes, and ecological impacts. By critically examining existing studies, the evaluation identifies trends, gaps, and challenges in the application of zooremediation. Conclusion: Future research should focus on understanding the long-term impacts, optimizing protocols, and safeguarding both ecological and animal health to fully realize the potential of zooremediation in managing environmental pollution on a global scale.
Exploring the Pharmacological Potential of Centella asiatica: A Metabolomic Perspective on a Traditional Medicinal Plant Aini, Fadita Nurul; Yuwana, Cynthia Putri; Maryenti, Tety; Nisa, Upi Chairun; Yuniati, Ratna; Handayani, Windri; Yasman, Yasman
BIOEDUSCIENCE Vol 10 No 1 (2026): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18857

Abstract

Background: Centella asiatica, also known as Gotu Kola or Pennywort, is a medicinal herb with a long history of use in traditional systems such as Mediterranean Herbal Medicine, Ayurveda, and Traditional Chinese Medicine. Its longstanding use highlights its importance as a natural remedy for various health conditions.   Methods: Recent metabolomics-based studies have advanced our understanding of its pharmacological potential by identifying key bioactive compounds—including phenolics, triterpenoids, and saponins—through analytical techniques such as GC-MS, LC-MS, and NMR.   Results: These compounds contribute to a range of therapeutic effects, notably antioxidant and antibacterial activities. C. asiatica has demonstrated efficacy against antibiotic-resistant pathogens like Staphylococcus aureus and Pseudomonas aeruginosa, as well as the ability to mitigate oxidative stress.   Conclusions: The integration of pharmacological and metabolomics approaches has highlighted its potential for development into herbal medicines and health supplements. While further research is warranted to optimize formulation and clinical application, existing evidence provides a solid foundation for the advancement of C. asiatica as a natural product for promoting human health and addressing antimicrobial resistance.
The Threat of Aquatic Invasive Species: Understanding and Addressing Biological Pollution Cynthia Putri Yuwana; Windri Handayani; Upi Chairun Nisa; Tety Maryenti; Ratna Yuniati; Yasman Yasman
Jurnal Ilmu Lingkungan Vol 23, No 3 (2025): May 2025
Publisher : School of Postgraduate Studies, Diponegoro Univer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jil.23.3.678-687

Abstract

This review explores the impact of aquatic invasive species as biological pollutants that disrupt ecosystems globally, including in Indonesia. Invasive species often exhibit rapid growth and reproduction due to their adaptive advantages, which, combined with human activities and favorable environmental conditions, accelerate their spread. These species alter the balance of marine and freshwater ecosystems, posing significant challenges for biodiversity conservation and resource management. Various regulatory measures have been implemented internationally, such as the European Union’s blacklist of invasive species and Indonesia’s legislative framework, to prevent their spread. Additionally, remediation techniques like zooremediation, using bivalves to mitigate biological pollutants, have been applied to manage these species. The review also highlights challenges in controlling invasive species, including the need for comprehensive ecosystem assessments and strategies like Top-Down and Bottom-Up modeling for management. Ultimately, a deeper understanding of the invasive species' ecological effects is essential for developing more effective control measures and policies, ensuring the protection of aquatic environments and mitigating the global spread of invasive species.
Morphometric analysis of Gorontalo (Indonesia) native chickens from six different regions ALFI SOPHIAN; ABINAWANTO ABINAWANTO; UPI CHAIRUN NISA; FADHILLAH FADHILLAH
Biodiversitas Journal of Biological Diversity Vol. 22 No. 4 (2021)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d220420

Abstract

Abstract. Sophian A, Abinawanto, Nisa UC, Fadhillah. 2021. Morphometric analysis of Gorontalo (Indonesia) native chickens from six different regions. Biodiversitas 22: 1757-1763. Research on the diversity of Gorontalo native chickens based on morphometric analysis of body weight, leg length, head length, head length to beak and head width was conducted. This study was conducted to identify the diversity of native chickens in six regions spread across Gorontalo Province, Indonesia. The method used in conducting statistical analysis is the principal component analysis (PCA) method. This method was performed to identify which morphometric factors play a role in relationship analysis of Gorontalo native chickens. Based on statistical analysis, it was found that of the 5 variables used in this study, 3 variables had Measure of Sampling Adequacy (MSA) values > 0.5 ranged from 0.537 to 0.648, namely body weight, leg length, and head length. Meanwhile, the other 2 variables, namely Head to Beak Length and Head Width, have MSA values <0.5 with values of 0.313 and 0.316. This causes the other 2 variables to be used as a differentiating variable in analyzing the relationship between native chickens from six different regions scattered in the Gorontalo Province. The morphometric analysis of body weight means that the chickens sampled from Boalemo were morphometrically the largest in size, while the chickens sampled from Pohuwato were morphometrically the smallest. Chickens sampled from North Gorontalo, Bone Bolango, and Gorontalo City tended to be more uniform when compared to the chickens sampled from Pohuwato and Boalemo areas, while for Gorontalo District it was larger in size than Pohuwato, North Gorontalo, Bone Bolango, and Gorontalo City, but smaller than Boalemo.