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Sensitivity and Specificity of Ultrasonography for Assessing Axillary Lymph Nodes in Breast Cancer Patients in Surakarta, Indonesia Bellynda, Monica; Yarso, Kristanto Yuli; Rosati, Ari; Kamil, Muhammad Rizki; Muhammad, Faizal
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1339

Abstract

Background: Breast cancer is the most common malignancy in women worldwide. Early detection is effective in reducing breast cancer mortality by 25–30%. Staging assessment with sentinel lymph node biopsy (SLNB) is the gold standard for patients with clinically negative axillae. Ultrasound examination of the axillae is often performed as a preoperative treatment for breast cancer patients to determine the stage of the cancer, where regional axillary lymph node assessment can be related to the prognostic factors of breast cancer, as well as assessing the prognosis for distant metastases. This study aims to evaluate the sensitivity of ultrasound examination of the axillary lymph nodes in breast cancer.Method: This study employs a descriptive research method with a retrospective approach, utilizing secondary data and comprising 283 samples. Inclusion criteria included patients diagnosed with cervical carcinoma confirmed by histopathological evaluation and complete medical records documenting age, primary complaints, histopathological classification, and TNM staging. Data were processed and presented using descriptive statistics. The study was conducted at the Surakarta Hospital between 2020 and 2022. Inclusion criteria were breast cancer patients with stage T1-2 N0 M0 confirmed by histopathological examination who underwent axillary lymph node ultrasound examination in Surakarta. Data was taken from the medical records. Patient's initial, age, date of examination, clinical diagnosis, expertise of the ultrasound, and histopathology of the axillary lymph node were recorded. The gold standard is SLNB. The calculation of diagnostic validity was carried out using a 2x2 table, and then the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of ultrasound were calculated.Results: 176 cases met the inclusion criteria, with 59.10% patients aged over 50 years old. Seventeen cases had positive ultrasound but negative histopathology examinations. Meanwhile, the remaining 15 cases had negative ultrasound but positive histopathology examinations. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy results are as follows: 82%, 83%, 80%, 83%, 4.89, 0.21, and 82%, respectively.Conclusion: Ultrasound examination for assessing axillary lymph nodes is easy, inexpensive, effective, and safe. The results can be increased with better radiological methods and experience from higher-level operators.
Myxofibrosarcoma of The Abdominal Wall at Moewardi Hospital, Surakarta: A Rare Case Report Soewoto, Widyanti; Ismail, Erwin Aritama; Bellynda, Monica
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1018

Abstract

Introduction: Myxofibrosarcoma (MFS) is a fibroblast-derived sarcoma, which accounts for approximately 5–10% of all soft tissue malignant tumors. The mean age in patients with MFS is between the fifth and seventh decades. Around 77% of MFS cases occur in the upper extremities. Other areas of the body including the trunk (12%), retroperitoneum or mediastinum (8%), abdominal wall, and heart have also been reported. Case Presentation: A 57-year-old Indonesian female visited our center with complaints of a lump in the left lower abdomen for 4 months. The lump has grown rapidly in the last two months. A contrast abdominal MRI examination found a soft tissue mass on the left lumbar abdominal wall to the left iliac with a size of 15 x 11,4 x 13,4 cm and bordered by part of the left external oblique muscle and the left internal oblique muscle pushing the intestinal system medially. The biopsy of the mass revealed a high-grade myxofibrosarcoma. The patient underwent a wide excision with an elliptical incision design, with in-toto removal of the lump. The immunohistochemical result of the tumor showed high-grade myxofibrosarcoma with free margins at the incision margin. Follow-up was performed at 1 month, 6 months, and 12 months postoperatively. The patient did not receive radiotherapy. Conclusions: This report describes a rare case of MFS of the abdominal wall. Recognizing the histopathological features of MFS and applying the appropriate immunohistochemical examinations are crucial in establishing the correct diagnosis. This case provides a diagnosis and treatment experience of MFS that occurs in the abdominal wall.