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Imma Irfani, Qonita
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Other

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Tata Laksana Onikomikosis Candida: Tinjauan Pustaka Imma Irfani, Qonita
Cermin Dunia Kedokteran Vol 52 No 9 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i9.1373

Abstract

Onychomycosis, also known as tinea unguium, is a fungal infection of the nail that can be caused by various types of fungi, including dermatophytes, non-dermatophyte molds, and yeasts. One specific type is candidal onychomycosis, which is caused by yeasts, particularly those from the Candida genus. This nail infection may affect all parts of the nail unit, including the nail plate, matrix, and surrounding tissue. Common clinical manifestations include nail discoloration—typically yellow or brown—thickening or softening of the nail, and increased nail fragility. Onychomycosis is one of the most frequently encountered nail disorders, with an estimated prevalence of approximately 50% of all complaints related to nail disease. Given the diverse etiologies of nail infections and broad differential diagnoses, laboratory examination is strongly recommended prior to initiating treatment. Diagnostic methods such as direct microscopy, fungal culture, and molecular testing are essential for accurate identification, enabling more targeted, effective, and cost-efficient therapy.
Prevalensi, Pola Kepekaan Antibiotik serta Perbandingan kejadian MRSA antara pasien laki-laki dan perempuan di Rumah Sakit dr. Soeradji Tirtonegoro Imma Irfani, Qonita; Lusinta, Hesty
MJS Medical Journal of Soeradji Vol 1 No 1 (2024): MJS (Juli)
Publisher : RSUP dr.Soeradji Tirtonegoro Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70605/vhnpwf29

Abstract

Latar Belakang: Infeksi yang di sebabkan oleh bakteri Staphylococcus aureus yang resisten terhadap obat golongan methicillin atau MRSA merupakan masalah kesehatan yang saat ini terjadi serta menyebabkan hasil luaran yang fatal dengan progresifitas yang cepat, serta risiko kematian yang tinggi Tujuan: mengetahui prevalensi, pola kepekaan antibiotik dan perbandingan kejadian infeksi MRSA pada pasien laki-laki dan perempuan yang teridentifikasi di laboratorium Mikrobiologi Klinik RSUP dr. Soeradji Tirtonegoro. Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross-sectional yang dilakukan secara retrospektif dalam kurun waktu satu tahun yaitu mulai 1 Januari 2023 sampai dengan 31 Desember 2023. Hasil: isolat MRSA yang terdeteksi ialah 1,2%, dan lebih banyak didapatkan dari pasien laki-laki (52,6%), dan mayoritas didapatkan dari sampel pus dan swab luka dan masih memiliki nilai sensitifitas yang baik untuk antibiotik Linezolid dan Vancomycin. Kesimpulan: hasil Analisa Chi square yang dilakukan menunjukan bahwa tidak terdapat perbedaan proporsi kejadian MRSA baik untuk laki-laki maupun perempuan dengan nilai p sebesar 0,580165 Kata Kunci: Infeksi, Staphylococcus aureus, MRSA.
Analisis Pola Bakteri dan Faktor Risiko Bakteremia pada Unit Perawatan Intensif Dewasa di Rumah Sakit Umum Soeradji Tirtonegoro Klaten, Indonesia: Penelitian Imma Irfani, Qonita
Cermin Dunia Kedokteran Vol 53 No 03 (2026): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i03.1814

Abstract

Introduction: Bloodstream infections (BSI) are life-threatening and pose an increased risk of mortality, particularly in intensive care patients. This study aims to delineate the bacterial patterns and analyze the risk factors associated with bacteremia among patients in the adultintensive care unit at Soeradji Tirtonegoro Hospital. Methods: This study used a descriptive-analytical design with a cross-sectional approach. The study population consisted of all adult ICU patients at Soeradji Tirtonegoro Hospital with positive blood cultures during the treatment period from October 1, 2019, to August 31, 2022. Analysis of risk factors associated with bacteremia was performed using Fisher's exact test. Results: Analysis shows a significant association between the accumulation of 3 or more risk factors and the bacterial patterns found in patients with bacteremia. Data from 52 patients were selected for analysis, comprising 21 females and 31 males. The risk factors associated with bacteremia included installation of hemodialysis catheters, water-sealed drainage (WSD), ventilator use, a history of diabetes, and previous surgery. Several patients had more than one risk factor associated with bacteremia. Blood culture results revealed that 30 out of 52 cases (57.7%) were caused by Gram-negative bacteria, while 22 out of 52 cases (42.3%) were caused by Gram-positive bacteria. The analysis identified two cases of methicillin-resistant coagulase-negative staphylococci (MR CoNS), but no methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamases (ESBLs) or carbapenemase-producing bacteria were found. Conclusion: This study identified bacterial patterns and analyzed risk factors associated with bacteremia in adult intensive care units. There was a significant association between the number of accumulated risk factors and specific bacterial pathogens in patients with bacteremia.
Co-Authors Lusinta, Hesty