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All Journal Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Jurnal Riset Sains dan Kimia Terapan
Juliandoz
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry

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FORMULASI EKSTRAK DAUN KITOLOD (HIPOBROMA LONGIFLORA) DALAM SEDIAAN OBAT KUMUR ALAMI TERHADAP BAKTERI STREPTOCOCCUS MUTANS Situmeang, Boima; Dzulhijar; Juliandoz; Ahmad Fajar Muzakir; Agus Malik Ibrahim; Nani Yulianti; Nurhayati Bialangi; Weny JA Musa
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 7 No. 2 (2025): Literasi Artikel Penelitian Kimia
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v7i2.5802

Abstract

The kitolod plant (Hippobroma longiflora) has been demonstrated to possess antibacterial activity against Streptococcus mutans, the bacterium responsible for the development of dental caries. The objective of this study was to formulate a mouthwash preparation using kitolod leaf extract. The extract was formulated into three distinct formulations. The mouthwash was evaluated for its pH, viscosity, stability, and antibacterial activity. The antibacterial evaluation was executed in accordance with the Kirby-Bauer method. The positive control utilized in this study was 0.2% chlorhexidine. The pH test results indicated that all three formulations had a pH of 6. The viscosity test demonstrated that all formulations had a viscosity of 0.99, which is close to that of water. The antibacterial evaluation against S. mutans indicated that formulation 2 demonstrated the most pronounced antibacterial activity, exhibiting an inhibition zone measuring 3.81 mm. All three formulations exhibited stability at ambient temperature. In light of the findings from this study, it can be posited that formulation 2 possesses the potential to serve as a natural mouthwash.
Potential of the Ethyl Acetate Extract of Kesambi (Schleichera oleosa) Bark as an Ointment-Based Treatment for Skin Diseases Against Staphylococcus aureus Juliandoz; Dzulhijar; Ningrum, Sekar Ayu; Situmeang, Boima; Yulianti, Nani; Bilangi, Nurhayati; Musa, Weny Junus Abdul; Rondonuwu, Mervina
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.03

Abstract

One plant with potential to treat skin diseases is the Kesambi plant. Based on community experience in Cilegon, a decoction of Kesambi tree bark has been used to treat skin ailments, including itching, insect bites, and scabies. This research aims to reveal the potential of ethyl acetate extract from the tree bark as a standardized ointment preparation. Extraction was performed using the maceration method. Quality testing of the ointment included antibacterial, safety, stability, organoleptic, and bioactive compound content testing. The best formulation was formulation 1, with an antibacterial inhibition zone of 0.6-0.7 mm, classified as moderate. Increasing the amount of extract did not significantly affect antibacterial activity. The bioactive compound content in the ointment consisted of compounds from the groups of triterpenoids, steroids, phenolics, and flavonoids.
Co-Authors Agus Malik Ibrahim Ahmad Fajar Muzakir Bilangi, Nurhayati Boima Ramses Situmeang Dzulhijar Mervina Rondonuwu Musa, Weny Junus Abdul Nani Yulianti Ningrum, Sekar Ayu Nurhayati Bialangi Situmeang, Boima Weny JA Musa