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All Journal Jurnal Riset Sains dan Kimia Terapan
Musa, Weny Junus Abdul
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Chemistry

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Potential of the Ethyl Acetate Extract of Kesambi (Schleichera oleosa) Bark as an Ointment-Based Treatment for Skin Diseases Against Staphylococcus aureus Juliandoz; Dzulhijar; Ningrum, Sekar Ayu; Situmeang, Boima; Yulianti, Nani; Bilangi, Nurhayati; Musa, Weny Junus Abdul; Rondonuwu, Mervina
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.03

Abstract

One plant with potential to treat skin diseases is the Kesambi plant. Based on community experience in Cilegon, a decoction of Kesambi tree bark has been used to treat skin ailments, including itching, insect bites, and scabies. This research aims to reveal the potential of ethyl acetate extract from the tree bark as a standardized ointment preparation. Extraction was performed using the maceration method. Quality testing of the ointment included antibacterial, safety, stability, organoleptic, and bioactive compound content testing. The best formulation was formulation 1, with an antibacterial inhibition zone of 0.6-0.7 mm, classified as moderate. Increasing the amount of extract did not significantly affect antibacterial activity. The bioactive compound content in the ointment consisted of compounds from the groups of triterpenoids, steroids, phenolics, and flavonoids.
Co-Authors Bilangi, Nurhayati Dzulhijar Juliandoz Mervina Rondonuwu Nani Yulianti Ningrum, Sekar Ayu Situmeang, Boima