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All Journal Dental Journal (Majalah Kedokteran Gigi) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Journal of Fisheries & Marine
Afroz, Shaista
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Public Health

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Global Research Trends on Oral Diseases Amid the Double Burden of Diabetes and Tuberculosis: A Bibliometric Analysis Arinawati, Dian Yosi; Tinartayu, Seshy; Ulfa, Maria; Afroz, Shaista
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 8 No. 9 (2025): September 2025
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v8i9.7852

Abstract

Introduction: Diabetes Mellitus (DM) and Tuberculosis (TB) present significant health challenges in low- and middle-income countries (LMICs). DM increases the risk of active TB by 2 to 4 times due to weakened immunity, and the number of adults with DM is projected to rise from 463 million in 2019 to 700 million by 2045, with 80% in LMICs where TB is common. This co-occurrence complicates treatment, as TB can worsen glycemic control and poorly managed DM affects immunity. Although DM is linked to periodontitis and TB can cause ulcers, the oral health implications remain underexplored. The objective was to identify research themes and collaboration networks for improving oral healthcare among patients with tuberculosis and diabetes mellitus comorbidities, who also have oral diseases. The broader aim is to improve oral healthcare and reduce the burden of chronic diseases in these populations. Methods: A qualitative literature review was conducted using peer-reviewed journals from 2018 to 2024 in the Scopus database. The search employed the keywords “oral AND diseases AND tuberculosis AND diabetes AND mellitus,” focusing solely on English documents in various medical fields. Data collection in March 2025 aimed to minimize bias. Descriptive and bibliometric analyses were performed using RStudio and VOSviewer to examine trends and correlations among oral diseases, tuberculosis, and diabetes mellitus. This analysis is conducted through cocitation and keyword patterns. Results: A review of 146 publications from 2018 to 2024 found that only six (4.1%) focused on oral health in tuberculosis and diabetes mellitus (TB-DM). The average annual growth rate of publications was 8.89%. Four main themes emerged: (1) complications of diabetes mellitus, (2) tuberculosis examination and treatment, (3) prevalence and risk factors of type 2 diabetes, and (4) TB-DM interactions. India, the USA, and Japan were the leading contributors. The top keywords were "diabetes mellitus" (900), "tuberculosis" (735), and "non-insulin-dependent diabetes mellitus" (431). Conclusion: Future research should adopt an interdisciplinary approach to investigate the effect of systemic inflammation and medication interactions on oral health in DM-TB populations. Longitudinal studies are necessary to assess the impact of oral interventions on glycemic control and treatment success for TB. Collaboration among dental and medical professionals is essential for delivering integrated care models that prioritize both oral and systemic health.
Saltwater Fish Nanoparticles: Biological Effects on COL1A1 Expression in Fetal Mice and Tablet Formula Optimization Christiono, Sandy; Hutami, Islamy Rahma; Suparmi, Suparmi; Afroz, Shaista; Clarasya, Amara Danish; Ahmad, Rayyan Orvin Pradipta; Subiyono, Amelia Febriani
Jurnal Ilmiah Perikanan dan Kelautan Vol. 18 No. 1 (2026): JURNAL ILMIAH PERIKANAN DAN KELAUTAN
Publisher : Faculty of Fisheries and Marine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jipk.v18i1.76746

Abstract

Graphical Abstract  Highlight Research Saltwater fish Nano powder modulates the expression of matrix proteins, influencing early dental tissue development. Administration significantly decreases COL1A1 expression in fetal mouse teeth, affecting biomineralization. Increasing talc concentration improves flowability and formulation stability by reducing angle of repose, Carr’s index, and Hausner ratio. Findings suggest marine-derived nanoparticles regulate cellular differentiation during dental development. Supports potential applications of marine natural materials in prenatal nutrition and dental tissue engineering.   Abstract Saltwater fish nanoparticle-based tablets represent a novel nutritional strategy aimed enhancing dental hard tissue density, particularly enamel. These tablets incorporate bioactive proteins, omega-3 fatty acids, and essential minerals such as calcium, phosphate, and magnesium to support enamel biomineralization. The nanoparticle formulation facilitates efficient cellular absorption, thereby increasing the expression of key enamel proteins like collagen type I alpha 1 chain (COL1A1) during enamel matrix development. This study investigated the effect of saltwater fish nanoparticles on COL1A1 expression in ameloblast cells and evaluated the physicochemical properties of tablets with talc concentrations of 1%, 5%, and 10%. Using a true experimental design with a post-test only control group, two groups of mice were assigned: a control group fed standard diet, and a treatment group fed a standard diet supplemented with saltwater fish nanoparticles (2.17 mg/0.5 mL). Tablet formulations were analyzed across the three talc concentrations. Data were subjected to independent T-tests for COL1A1 expression and One-way ANOVA for physicochemical properties. Results revealed a significant reduction in COL1A1 expression in the treatment group. Additionally, talc concentration significantly influenced tablet physicochemical characteristics, with the 10% talc formulation exhibiting the most optimal properties. These findings suggest potential for nanoparticle-based nutritional interventions to promote enamel formation.
Influence of oral aesthetics on overall appraisal of facial aesthetics Abirami , S.; Afroz, Shaista; Nawab, Tabassum; Rajput, Geeta
Dental Journal (Majalah Kedokteran Gigi) Vol. 59 No. 1 (2026)
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v59.i1.p55-62

Abstract

Background: Uneven dentition is a cause of dissatisfaction to many. However, irregularities in teeth may be less unattractive when viewed from a full-face perspective than from a circumoral view. Purpose: To ascertain the influence of dental aesthetics (DA) on the overall appraisal of facial aesthetics (FA) and to compare the perception of the general population with that of dental experts. Methods: Frontal and circumoral view photographs with mild-to-moderate dental asymmetries were selected for FA and DA evaluation. Participants from the general population assessed attractiveness using a questionnaire (validated in a pilot study) with questions on FA and DA. Dental experts assessed attractiveness using the Dental Esthetic Screening Index with extraoral and intraoral components. Smile mesh measurements were taken to calculate the various attributes of smiles. Results: The experts considered that all the images had insufficient-to-good aesthetics (mean score: 20.82±6.545), and a statistically significant correlation was identified between the two variables (R2=0.04, p=0.0015). The general population considered all the images to have satisfactory-to-good aesthetics (mean score: 15.8±3.006), and no correlation was identified between the two variables for all the images taken individually and cumulatively (R2=0.002, p=0.46). It was observed that there was a statistically significant correlation between patient scores as the dependent variable and expert scores as the independent variable (R2=0.24, p<0.001). Conclusion: Facial attractiveness overshadowed dental irregularities and influenced the general population’s judgment; however, the dental experts’ judgment was influenced by intraoral aesthetics.
Co-Authors Abirami , S. Ahmad, Rayyan Orvin Pradipta Clarasya, Amara Danish Dian Yosi Arinawati Islamy Rahma Hutami, Islamy Rahma Maria Ulfa Nawab, Tabassum Rajput, Geeta Sandy Christiono Subiyono, Amelia Febriani Suparmi Suparmi Tinartayu, Seshy