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All Journal Jurnal Pembelajaran dan Biologi Nukleus Journal of Energy, Material, and Instrumentation Technology Medika: Jurnal Ilmiah Kesehatan
Tresnaningtyas, Sekar Asri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Prevalensi Infeksi Cytomegalovirus (CMV) Berdasarkan Jenis Sampel dan Karakteristik Pasien Balita di Laboratorium Pusat Diagnostik dan Riset Penyakit Infeksi Universitas Andalas Tahun 2023–2024 Tresnaningtyas, Sekar Asri; Putra, Andani Eka; Farashanda, Meysha; Fahma, Siskalil; Hanif, Monica Mulnia
Medika: Jurnal Ilmiah Kesehatan Vol 5 No 2 (2025): Medika: Jurnal Ilmiah Kesehatan
Publisher : Universitas Nahdlatul Ulama Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69503/medika.v5i2.1126

Abstract

Infeksi Cytomegalovirus (CMV) merupakan salah satu infeksi virus yang berpotensi serius pada anak balita, terutama karena potensi komplikasi jangka panjang. Penelitian ini bertujuan untuk mengetahui prevalensi CMV berdasarkan jenis sampel (urin dan darah) serta karakteristik pasien balita yang diperiksa di Laboratorium Pusat Diagnostik dan Riset Penyakit Infeksi Fakultas Kedokteran Universitas Andalas selama tahun 2023 hingga 2024. Penelitian dilakukan secara deskriptif analitik terhadap 87 data pasien anak usia 0–28 bulan. Analisis statistik meliputi uji Kruskal-Wallis, chi-square, dan McNemar. Hasil menunjukkan bahwa sebagian besar pasien memiliki hasil positif CMV pada kedua spesimen, yaitu urin dan darah (42,5%), diikuti oleh positif hanya pada urin (18,4%), hanya pada darah (14,9%), dan negatif pada keduanya (24,1%). Tidak terdapat hubungan signifikan antara jenis kelamin atau usia dengan hasil CMV. Uji McNemar menunjukkan tidak ada perbedaan bermakna antara hasil pemeriksaan urin dan darah (p = 0,710). Dapat disimpulkan bahwa baik urin maupun darah memberikan hasil yang sebanding, meskipun dengan konsistensi terbatas.
Fabrication of Bioceramic Carbonated Hydroxyapatite–Chitosan Composite Scaffold Derived from River Snail Shells via Freeze-Drying for Bone Grafting Applications Wati, Rosita; Alnovera, Vayza Deva; Herbanu, Aldi; Endah; Tresnaningtyas, Sekar Asri; Gifari, Muhammad Wildan; Siburian, Marsudi
Journal of Energy, Material, and Instrumentation Technology Vol 6 No 4 (2025): Journal of Energy, Material, and Instrumentation Technology (In Press)
Publisher : Departement of Physics, Faculty of Mathematics and Natural Sciences, University of Lampung

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Abstract

Phytochemical Profiling and Granule Formulation of Green Betel Leaf (Piper betle L.) Extract for Potential Bio-Larvicidal Application Mahardianti, Meita; Nurani, Puspa Rini Cahaya; Tresnaningtyas, Sekar Asri; Islami, Suryadi
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 11, No 4: Jurnal Pembelajaran Dan Biologi Nukleus December 2025
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v11i4.8448

Abstract

Background: The increasing spread of Aedes aegypti as a vector of dengue disease has encouraged the exploration of safer, plant-based larvicidal materials. This study aimed to identify the phytochemical constituents of green betel leaf (Piper betle L.) extract and to develop a bio-larvicidal granule formulation as a modified dosage form. Phytochemical screening was conducted to identify bioactive compounds potentially associated with larvicidal activity. Methodology: Granules were prepared using the wet granulation method, employing polyvinylpyrrolidone (PVP) as a binder and lactose as a filler. The formulated granules were further evaluated through physical characterization tests, including flow rate, angle of repose, and dispersion time, to assess their suitability as a granular dosage form. Findings: The results demonstrated that all formulations exhibited acceptable flow properties, appropriate angles of repose, and rapid dispersion in water, indicating favorable handling and application characteristics. The flow rate test results showed that granules with concentration variations of 25%, 50%, 75%, and 100% exhibited flow rates of 71.4 g/s, 62.5 g/s, 50 g/s, and 45.5 g/s, respectively. Physical evaluation demonstrated that the granules had acceptable angles of repose (31°–36°) and dispersion time (20–25 seconds). Contribution: This study was conducted as a step toward developing an environmentally safe, natural-material-based biolarvicide
Co-Authors Alnovera, Vayza Deva Andani Eka Putra Endah Fahma, Siskalil Farashanda, Meysha Gifari, Muhammad Wildan Hanif, Monica Mulnia Herbanu, Aldi Mahardianti, Meita Nurani, Puspa Rini Cahaya Rosita Wati Siburian, Marsudi Suryadi Islami