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Immunomodulatory Activity of Ganyong Tuber (Canna edulis K.) Extract on Phagocytosis, Leukocytes, and Antibody of Mice against Bacterial Infections Savira, Nadyatul Ilma Indah; Qulbi, Siti Shofa Assyifa; Marditianingsih, Meilia Putri; laili, Mumtahana; Narulita, Erlia; Pramudya, Manikya; Maulana, Alfan Irsyad
Majalah Biomorfologi Vol. 35 No. 2 (2025): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v35i2.2025.113-122

Abstract

Highlights Ganyong tuber exhibits immunomodulatory activity against Staphylococcus aureus infection in mice. Ganyong tuber extract increases phagocytic activity, leukocyte count, and spleen weight in infected mice.   ABSTRACT Background:  Ganyong tubers (Canna edulis K.) are widely consumed by Indonesians as an alternative food source. However, no studies have investigated the pharmacological properties of ganyong tubers, particularly their immunomodulatory activity. Objective: This study aimed to evaluate the immunomodulatory effects of ganyong tubers in mice infected with Staphylococcus aureus. Material and Method: This study used a randomized experimental design involving 30 male BALB/c mice divided into five groups, including a normal control, a negative control (infected with Staphylococcus aureus), and three groups treated with ganyong (Canna edulis K.) extract at doses of 50, 100, and 150 mg/kg BW. The extract was administered orally for seven days, followed by S. aureus injection. Phagocytic activity, leukocyte count, spleen weight, and antibody levels were evaluated using microscopy and ELISA. Data were analyzed using one-way ANOVA and Duncan’s post hoc test. Result: This study evaluated the immunomodulatory effects of ganyong tuber (Canna edulis K.) extract on phagocytosis activity and capacity, leukocyte count, spleen weight, and antibody levels in mice infected with Staphylococcus aureus. Phagocytosis activity and capacity were highest in the group receiving 50 mg/kg body weight (BW) extract, with decreasing effects at higher doses. Leukocyte counts were highest in the infected untreated group, while spleen weight was significantly increased in the 50 mg/kg BW treatment group compared to controls. Although the 100 mg/kg BW group showed the highest antibody levels, these differences were not statistically significant. Conclusion: Ganyong tuber extract demonstrated immunomodulatory activity by enhancing innate immune responses against S. aureus infection.
A Systematic Review of Critical Thinking Assessment Instruments in Junior High School Science Education: Trends, Effectiveness, and Challenges Barid, Siti Shofa Assyifa’ul Qulbi; Gunawan, Arvidhea Safira; Yusmar, Firdha; Astuti, Soekma Yeni; Wahyuni, Sri
Science Education and Application Journal Vol 7 No 2 (2025): Science Education and Application Journal
Publisher : Program Studi Pendidikan IPA, Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/seaj.v7i2.1308

Abstract

This systematic literature review, conducted using the PRISMA method, synthesizes research on the development of critical thinking assessment instruments in junior high school science education between 2016 and 2025. Secondary data were obtained through the Publish or Perish application with sources from Google Scholar, keywords include science learning, assessment instruments, and critical thinking. By analyzing 7 peer-reviewed national journals, the study evaluates the validity, reliability, and effectiveness of these tools in enhancing students' critical thinking skills. The findings highlight diverse assessment models, their impact on student learning outcomes, and the challenges faced by educators in implementing these tools. This review offers recommendations for improving the design and application of critical thinking assessments in science curricula.
Persepsi dan Tantangan Pembelajaran Koding dalam Mata Pelajaran IPA sebagai Penguatan Keterampilan Abad-21 Barid, Siti Shofa Assyifa’ul Qulbi; Gunawan, Arvidhea Safira; Nur, Syinta
Panthera : Jurnal Ilmiah Pendidikan Sains dan Terapan Vol. 5 No. 4 (2025): October
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/panthera.v5i4.678

Abstract

Coding education in schools serves not only as a technical skill, but also supports the development of 21st-century skills such as critical thinking, problem solving, collaboration, creativity, and computational thinking. The purpose of this study is to analyze perceptions and challenges in coding education in science education. A systematic literature review using the PRISMA approach was used in this research. This study began with developing research questions, selection criteria, search strategies, research article selection processes, research article quality assessments, and synthesis of selected articles. Data were collected by identifying articles related to perceptions and challenges of coding learning in science subjects, covering 200 articles related to coding learning published between 2020 and 2025, and 12 articles that met the criteria were obtained. The results showed that coding learning integrated into science subjects in junior high school had a significant contribution to developing 21st-century skills. However, the challenges faced included a lack of teacher competence in coding, limited resources, and the unavailability of a curriculum that supported the systematic integration of coding. These findings emphasized the importance of teacher training and the development of educational policies that were adaptive to current technology.
STUDI LITERATUR: PENGEMBANGAN LKPD UNTUK MENINGKATKAN LITERASI SAINS SISWA SMP PADA PEMBELAJARAN IPA Billah, Khofifah; Yusmar, Firdha; Rayendra Wahyu Bachtiar; Sri Wahyuni; Aushofil Karimah; Barid, Siti Shofa Assyifa’ul Qulbi
LENSA (Lentera Sains): Jurnal Pendidikan IPA Vol. 15 No. 2 (2025): November 2025
Publisher : Faculty of Teaching and Education, University of Wiraraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/lensa.v15i2.895

Abstract

Studi literatur: pengembangan LKPD untuk meningkatkan literasi sains siswa SMP pada pembelajaran IPA. Penelitian ini merupakan studi literatur yang bertujuan untuk mengkaji berbagai pengembangan Lembar Kerja Peserta Didik (LKPD) untuk meningkatkan literasi sains siswa SMP pada mata pelajaran IPA. Literasi sains dipahami sebagai kemampuan siswa dalam memahami konsep ilmiah, menerapkannya dalam kehidupan sehari-hari, serta mengambil keputusan berdasarkan data dan pertimbangan ilmiah. Metode penelitian yang digunakan dalam penelitian ini adalah metode systematic literature review mengacu pada pedoman PRISMA dengan meninjau berbagai artikel tahun 2021-2025. Kata kunci yang digunakan adalah “pengembangan LKPD", "literasi sains siswa SMP", dan "pembelajaran IPA. Dari 95 artikel diseleksi 6 artikel utama untuk dianalisis. Proses review terdiri dari lima tahapan yaitu menemukan literatur yang relevan, melakukan evaluasi sumber studi literatur, melakukan identifikasi tema, membuat struktur garis besar, dan menyusun ulasan studi literatur. Hasil kajian menunjukkan bahwa LKPD yang dirancang dengan pendekatan tersebut mampu meningkatkan literasi sains secara signifikan, baik dari aspek kognitif, afektif, maupun psikomotorik. Selain itu, pemanfaatan media digital seperti E-LKPD dan platform interaktif turut memperkuat efektivitas pembelajaran dan keterlibatan siswa. Dengan demikian, pengembangan LKPD berbasis literasi sains dapat menjadi strategi penting untuk menciptakan pembelajaran IPA yang aktif, kontekstual, dan relevan dengan kehidupan nyata siswa SMP.