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All Journal Indonesian Journal of Jamu Jurnal Pengabdian Masyarakat Inovatif Jurnal Pengabdian Masyarakat Inovatif
Tri Retno Handayani, Marybet
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Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Environmental Science Health Professions Medicine & Pharmacology Social Sciences Other

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Cardioprotective Effects of Red Ginger Extracted Using Natural Deep Eutectic Solvent on Lipid Profile in Atherosclerotic Rats Yulianita; Herlina, Nina; Tri Retno Handayani, Marybet; Al Aziz, Novan Masis; Safitri, Aditiya; Pamungkas, Ragil Raihan
Jurnal Jamu Indonesia Vol. 10 No. 3 (2025): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v10i3.410

Abstract

Atherosclerosis, a leading cause of cardiovascular disease, is closely related to dyslipidemia. This study evaluated the cardioprotective effects of red ginger (Zingiber officinale var. rubrum) extracted using a Natural Deep Eutectic Solvent (NADES) on lipid profiles and the risk of atherosclerosis in rats induced with an atherogenic diet and lipopolysaccharide (LPS). Thirty male Sprague-Dawley rats were divided into five groups: normal control, negative control, positive control (Simvastatin), and two treatment groups receiving red ginger extract at 25 mg/kg and 50 mg/kg body weight (BW). After 24 days of treatment, the 25 mg/kg BW dose significantly reduced total and LDL cholesterol while increasing HDL levels compared with the negative control (p < 0.05), showing comparable effects to Simvastatin. The 50 mg/kg BW dose did not significantly reduce total and LDL cholesterol but produced the highest HDL level. All treatment groups showed a significantly lower Atherogenic Index of Plasma (AIP) than the negative control, with the lowest AIP in the 50 mg/kg BW group. These findings demonstrate the cardioprotective potential of red ginger extracted with NADES as a natural, environmentally friendly approach to preventing dyslipidemia and atherosclerosis.
Training on Making Herbal Drink to Increase Immunity in Pagelaran Village, Ciomas, Bogor Tri Retno Handayani, Marybet; Yulianita; Wiendarlina, Ike Yulia; Utami, Novi Fajar; Mahyuni, Siti; Sulistiyono, Fitria Dewi; Komala, Oom; Hermawati, Ema; Rikkit
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.79

Abstract

Health is a very valuable factor in life. One way to improve health or immunity is by consuming herbal drinks. Herbal drinks are believed to have beneficial properties for healing disease. Livelihoods in Pagelaran Village are dominated by laborers, farmers, traders and domestic workers, with educational levels dominated by junior high and high school levels. The problems found in Pagelaran Village are public health problems, so it is necessary to improve welfare, one of which is by consuming healty drinks made from herbal plants. Red ginger is widely used to treat various diseases such as colds, digestive disorders, antipyretic, anti-inflammatory and also analgesic. Compounds of lemongrass that have a good prospects for increasing immune system activity are usually flavonoids, curcumin, limonoids, vitamin C, vitamin E (tocopherol) and catechins. Lemons also contain quercetin which can increase the body's immunity. This PKM activitiy was carried out in Agroeduwisata Lembah Watu, Pagelaran Village, Bogor Regency, took the form of training in making herbal drinks to increase body’s immunity for women of PKK and KWT. The implementation of this PKM activity can increase the knowledge of utilizing, processing and packaging herbal plants into herbal drink products. This PKM activity, it is hoped that people will be able to make and consume health drinks which can be used to increase the body’s immunity so that the quality of life can improves too.
Training on Making Herbal Drink to Increase Immunity in Pagelaran Village, Ciomas, Bogor Tri Retno Handayani, Marybet; Yulianita; Wiendarlina, Ike Yulia; Utami, Novi Fajar; Mahyuni, Siti; Sulistiyono, Fitria Dewi; Komala, Oom; Hermawati, Ema; Rikkit
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.79

Abstract

Health is a very valuable factor in life. One way to improve health or immunity is by consuming herbal drinks. Herbal drinks are believed to have beneficial properties for healing disease. Livelihoods in Pagelaran Village are dominated by laborers, farmers, traders and domestic workers, with educational levels dominated by junior high and high school levels. The problems found in Pagelaran Village are public health problems, so it is necessary to improve welfare, one of which is by consuming healty drinks made from herbal plants. Red ginger is widely used to treat various diseases such as colds, digestive disorders, antipyretic, anti-inflammatory and also analgesic. Compounds of lemongrass that have a good prospects for increasing immune system activity are usually flavonoids, curcumin, limonoids, vitamin C, vitamin E (tocopherol) and catechins. Lemons also contain quercetin which can increase the body's immunity. This PKM activitiy was carried out in Agroeduwisata Lembah Watu, Pagelaran Village, Bogor Regency, took the form of training in making herbal drinks to increase body’s immunity for women of PKK and KWT. The implementation of this PKM activity can increase the knowledge of utilizing, processing and packaging herbal plants into herbal drink products. This PKM activity, it is hoped that people will be able to make and consume health drinks which can be used to increase the body’s immunity so that the quality of life can improves too.
Co-Authors Al Aziz, Novan Masis Fitria Dewi Sulistiyono Hermawati, Ema Ike Yulia Wiendarlina Mahyuni, Siti Nina Herlina Novi Fajar Utami Oom Komala Pamungkas, Ragil Raihan Rikkit Safitri, Aditiya Yulianita