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The Potential of Natural Levodopa in Koro Benguk Seeds (Mucuna pruriens) for Treatment in Parkinson's Disease Maharani, Nyoman Ayu Anindya; Belynda Rahmalia Sanceska Wahyudi; Aisya Yafis Iqlima; Aisya Nur Abida; Maida sania salsabila; Devi Chandra Kirana; Andina Nabilah Mario; Herpan Syafii Harahap
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7265

Abstract

Mucuna pruriens also known as velvet bean (koro benguk) is a plant commonly found in tropical regions, including Indonesia. Mucuna pruriens is known to contain high levels of Levodopa, making it a potential natural treatment for Parkinson's disease. Parkinson's disease is a neurodegenerative disorder characterized by tremors, rigidity, bradykinesia, and postural instability. The estimated global incidence of Parkinson's disease in 2024 is expected to reach 12 to 17 million patients. Synthetic Levodopa has been the standard and proven effective therapy for Parkinson's disease. The method used in the preparation of this article is a literature review by collecting relevant and focused articles. The literature sources were accessed through comprehensive searches in three databases (Pubmed, Google Scholar, and Researchgate) from 2014 to 2024, using keywords such as “Mucuna pruriens,” “Levodopa,” and “Parkinson's disease.” The result of the literature review indicates that Levodopa is the dominant active component found in Mucuna pruriens compared to other compounds. The naturally occurring Levodopa functions as a precursor to dopamine, which plays a role in the treatment of Parkinson's disease, thus it can be developed into a complementary therapy in regions with abundant resources.
Relationship Between Screen Time and Physical Activity Among Adolescents Across the COVID-19 Pandemic Aisya Yafis Iqlima; Karuniawaty, Titi Pambudi; Wiguna, Putu Aditya
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7485

Abstract

The Covid-19 pandemic has caused changes in various aspects. The government's policy in order to suppress the spread of the Covid-19 virus in the form of restrictions on outdoor activities is shown from the results of various studies to affect the increase in screen time and decrease in physical activity. The purpose of this study was to determine the relationship between screen time and physical activity in adolescents before, during, and after the Covid-19 pandemic. The method used was quantitative research with an observational study that was analytical and a cross-sectional approach. Data collection was carried out using a questionnaire on 135 adolescents, including students from SMAN 1 Mataram and SMAN 5 Mataram. The results of the statistical test of screen time with physical activity before, during, and after the pandemic were p = 0.430, p = 0.426, and p = 0.198, respectively. Therefore, in this study it can be concluded that there is no relationship between screen time and physical activity before, during, and after the Covid-19 pandemic.