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All Journal Jurnal Biologi Tropis
Devi Chandra Kirana
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Complex Regional Pain Syndrome (CPRS): A Literature Review Amanullah, Mohammad Sany Rosafi; Ini Hidayat Makbul; Kadek Nandita Nugraha; Afif Farras; Baiq Inna Dwi Hardyningrat; Devi Chandra Kirana; Najla Aulia Yahya; Salsabila Dinda Nuril Ishlahi; Siti Nurhaliza; Shofia Kadarisma; Yunita Hapsari
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7731

Abstract

CRPS (Complex Regional Pain Syndrome) occurs due to tissue trauma, leading to inflammation, activation of peripheral nociceptors, and increased regulation of neuronal processes. The etiology of CRPS is not fully understood, but it is believed to be related to an inappropriate inflammatory response and dysfunction in the central and peripheral nervous systems. The purpose of this article is to provide additional information regarding CRPS, thereby facilitating more accurate diagnosis and effective treatment. The research method used is a literature review, which discusses the definition, etiology, epidemiology, pathophysiology, diagnosis, and management of Complex Regional Pain Syndrome (CRPS), drawing on sources from PubMed, ProQuest, ScienceDirect, and Google Scholar. Future research is essential to deepen the understanding of this syndrome and create opportunities for more effective prevention and treatment of CRPS.
The Potential of Natural Levodopa in Koro Benguk Seeds (Mucuna pruriens) for Treatment in Parkinson's Disease Maharani, Nyoman Ayu Anindya; Belynda Rahmalia Sanceska Wahyudi; Aisya Yafis Iqlima; Aisya Nur Abida; Maida sania salsabila; Devi Chandra Kirana; Andina Nabilah Mario; Herpan Syafii Harahap
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7265

Abstract

Mucuna pruriens also known as velvet bean (koro benguk) is a plant commonly found in tropical regions, including Indonesia. Mucuna pruriens is known to contain high levels of Levodopa, making it a potential natural treatment for Parkinson's disease. Parkinson's disease is a neurodegenerative disorder characterized by tremors, rigidity, bradykinesia, and postural instability. The estimated global incidence of Parkinson's disease in 2024 is expected to reach 12 to 17 million patients. Synthetic Levodopa has been the standard and proven effective therapy for Parkinson's disease. The method used in the preparation of this article is a literature review by collecting relevant and focused articles. The literature sources were accessed through comprehensive searches in three databases (Pubmed, Google Scholar, and Researchgate) from 2014 to 2024, using keywords such as “Mucuna pruriens,” “Levodopa,” and “Parkinson's disease.” The result of the literature review indicates that Levodopa is the dominant active component found in Mucuna pruriens compared to other compounds. The naturally occurring Levodopa functions as a precursor to dopamine, which plays a role in the treatment of Parkinson's disease, thus it can be developed into a complementary therapy in regions with abundant resources.
Co-Authors Afif Farras Aisya Nur Abida Aisya Yafis Iqlima Amanullah, Mohammad Sany Rosafi Andina Nabilah Mario Baiq Inna Dwi Hardyningrat Belynda Rahmalia Sanceska Wahyudi Herpan Syafii Harahap Ini Hidayat Makbul Kadek Nandita Nugraha Maharani, Nyoman Ayu Anindya Maida sania salsabila Najla Aulia Yahya Salsabila Dinda Nuril Ishlahi Shofia Kadarisma Siti Nurhaliza Yunita Hapsari