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Cross-Reactivity of Guillain-Barre Syndrome and Thrombotic Thrombocytopenic Purpura with Complications Respiratory Failure: Case Report Harlasgunawan, Alia Rahmi; Palo, Daud; Abdullah, Dirman; Priambodo, Ayu Prawesti; Mirwanti, Ristina
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3441

Abstract

Guillain-Barre Syndrome (GBS) and Thrombotic Thrombocytopenic Purpura (TTP) are two medical conditions that are rare but can cause serious complications if they appear simultaneously. Both conditions involve autoimmune mechanisms and can result in organ failure, including respiratory failure. Although there are several case reports of each condition, research exploring the interaction between GBS and TTP in the context of respiratory failure is limited. Purpose: The aim of this study is to describe a case of cross-reactivity of Guillian-Barre Syndrome and Thrombotic Thrombocytopenic Purpura with complications respiratory failure. Methods: This research uses a case study design involving an adult patient who was treated at a hospital in Bandung. Data was collected through a comprehensive nursing assessment. Patients provided informed consent before data were collected. Data analysis was carried out descriptively to describe clinical findings and patient management results. Results: The patient is a young woman 27 year old admitted to hospital with a diagnosis of GBS. Eleven days before entering the hospital the patient experience dascending paralysis, fever, nausea and vomiting.TTP cross-reactivity and peripheral nervous system inflammation in GBS.Complications of respiratory failure requiring invasive mechanical ventilation (IMV) in the ICU. Laboratory and radiological examinations supported the diagnosis, and medical intervention was performed according to protocol for both conditions. This shows the importance of close monitoring and prompt treatment to prevent further complications. These findings emphasize the need for a multidisciplinary approach in managing patients with complex medical conditions. Conclusion: An in-depth understanding of the interaction between GBS and TTP is essential for effective clinical management, especially in preventing and managing complications of respiratory failure.
PEMBERDAYAAN MASYARAKAT MELALUI AGENT OF CHANGE PENCEGAHAN STUNTING DI KELURAHAN PILOLODAA KECAMATAN KOTA BARAT KOTA GORONTALO Aswad, Ahmad; Adam, Lusiane; Suma, Juwita; Abdullah, Dirman
Devote: Jurnal Pengabdian Masyarakat Global Vol. 2 No. 2 (2023): Devote : Jurnal Pengabdian Masyarakat Global, Desember 2023
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/devote.v2i2.1936

Abstract

Stunting is a condition where a toddler has a length or height that is less than normal when compared to his age. Toddlers with growth delays may be at risk of decreased intelligence, decreased productivity and increased risk of degenerative diseases in the future. The purpose of this community service is to increase mothers' knowledge about nutritious food before pregnancy and after childbirth, use of clean water and sanitation. Pilolodaa Village was chosen as the location for the community service because it is one of the working areas of the West City Health Center which has the highest number of stunted children under five with a percentage of 28.46%. The method of implementing community service is carried out in the form of counseling using lecture methods, discussions, consultations, freezes, empowerment, mentoring and evaluation of knowledge about stunting prevention through a series of activities, namely licensing, coordination with the Kota Barat Health Center and Pilolodaa Village, preparing tools, media and places to use for program implementation. The results of the community service were an increase in knowledge about stunting prevention and an increase in skills in preparing nutritious food in the Pilolodaa Community Village, Kota Barat District, Gorontalo City.
Depresi Pada Pasien dengan Penyakit Jantung Koroner yang mengalami Left Ventricular Ejection Fraction Rendah : A Scoping Review Abdullah, Dirman; Anna, Anastasia; Nuraeni, Aan
MAHESA : Malahayati Health Student Journal Vol 6, No 4 (2026): Volume 6 Nomor 4 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i4.21468

Abstract

ABSTRACT Depression is one of the most common psychological comorbidities in patients with coronary heart disease, but research on patients with low left ventricular ejection fraction remains limited. This condition can worsen clinical prognosis and reduce patients' quality of life. This review aims to identify depression in coronary heart disease patients with low left ventricular ejection fraction. This study used a scoping review design. Literature searches were conducted in three main databases, namely EBSCOhost, PubMed, and ScienceDirect, as well as one additional search engine, Google Scholar. The keywords used included: “coronary heart disease OR myocardial infarction OR acute coronary syndromes OR unstable angina AND Low Left Ventricular Ejection Fraction OR Low LVEF AND Depression”. Inclusion criteria included: (1) studies involving patients with coronary heart disease, (2) studies evaluating the relationship between left ventricular ejection fraction and symptoms of depression, and (3) publications in English or Indonesian. Data analysis was performed using descriptive qualitative methods. A total of 707 studies were found in the literature search, which were then selected based on their titles and abstracts. A total of 7 out of 707 articles were analyzed in this review. Four of the seven studies reported that low left ventricular ejection fraction was associated with increased symptoms of depression in patients with coronary heart disease, especially after myocardial infarction. Meanwhile, the other two studies stated that there was no direct relationship but rather the influence of other factors such as social support and psychological history. Depression is a common condition in patients with coronary heart disease. Patients with coronary heart disease with low left ventricular ejection fraction are closely related to an increased risk of depression in CHD patients, and both worsen the clinical prognosis. Early detection and integrated management of depression are crucial for improving patients' quality of life and cardiovascular outcomes. A comprehensive approach encompassing pharmacological and psychosocial interventions has proven to be the most effective strategy for addressing depression in CHD patients. Keywords: Depression, Low Left Ventricular Ejection Fraction, Coronary Heart Disease.  ABSTRAK Depresi merupakan salah satu komorbid psikologis yang umum terjadi pada pasien dengan penyakit jantung koroner, namun penelitian pada pasien dengan left ventricular ejection fraction rendah masih sangat terbatas. Kondisi ini dapat memperburuk prognosis klinis dan menurunkan kualitas hidup pasien. Review ini bertujuan untuk mengidentifikasi depresi pada pasien penyakit jantung koroner yang mengalami left ventricular ejection fraction rendah. Studi ini menggunakan desain scoping review. Pencarian literatur dilakukan pada tiga database utama, yaitu EBSCOhost, PubMed, dan ScienceDirect, serta satu mesin pencari tambahan, Google Scholar. Kata kunci yang digunakan mencakup: “coronary heart disease OR myocardial infarction OR acute coronary syndromes OR unstable angina AND Low Left Ventricular Ejection Fraction OR Low LVEF AND Depression”. Kriteria inklusi meliputi: (1) studi yang melibatkan pasien dengan penyakit jantung koroner, (2) studi yang mengevaluasi hubungan antara left ventricular ejection fraction dan gejala depresi, serta (3) publikasi dalam bahasa Inggris atau Indonesia. Analisis data dilakukan secara deskriptif kualitatif. Pencarian literature didapatkan total sebanyak 707 studi yang kemudian diseleksi judul dan abstrak. Sebanyak 7 dari 707 artikel  dianalisis pada review ini. 4 dari 7 studi melaporkan bahwa left ventricular ejection fraction rendah berhubungan dengan meningkatnya gejala depresi pada pasien penyakit jantung koroner, terutama pasca-infark miokard. Sedangkan, dua studi lainnya menyatakan tidak adanya hubungan langsung melainkan pengaruh faktor lain seperti dukungan sosial dan riwayat psikologis. Depresi merupakan kondisi yang umum terjadi pada pasien penyakit jantung koroner. Pasien penyakit jantung koroner dengan tingkat left ventricular ejection fraction rendah berkaitan erat dengan peningkatan risiko depresi pada pasien PJK, dan keduanya saling memperburuk prognosis klinis. Deteksi dini dan manajemen depresi secara terintegrasi sangat penting untuk meningkatkan kualitas hidup dan hasil kardiovaskular pasien. Pendekatan komprehensif yang mencakup intervensi farmakologis dan psikososial terbukti menjadi strategi yang paling efektif dalam mengatasi depresi pada pasien PJK. Kata Kunci: Depresi, Left Ventricular Ejection Fraction Rendah, Penyakit Jantung Koroner.