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Assessment of Cryptococcal Meningitis Concurrent with Multidrug-Resistant Tuberculous Meningitis: A Case Report Elsadai, Elsadai; Priambodo, Ayu Prawesti; Mirwanti, Ristina; Sesilia, Fitri; Heriyansyah, Heriyansyah
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3489

Abstract

Cryptococcal meningitis is an infection that attacks the tissue lining the brain and spinal cord, caused by the fungus Cryptococcus neoformans. This infection mainly occurs in individuals with a weakened immune system, such as people with HIV/AIDS. The spread of this fungus into the central nervous system can result in serious conditions, even fatal if not treated quickly and appropriately. Objective: to present a rare and complex case report of a patient with concurrent cryptococcal meningitis and multiresistant tuberculous meningitis, as well as evaluate the management strategies used in the patient's care. Method: Case study was conducted through a comprehensive approach including health history assessment, physical examinations, psychosocial analysis, customized nursing assessment forms, electronic medical record reviews, laboratory diagnostics, imaging studies, and multidisciplinary consultations to ensure accurate diagnosis and effective interventions Mrs. R, a 33 year old woman with a final diagnosis including Pneumonia with aspiration mechanism, Cryptococcal Meningitis, Grade II MDR TB Meningitis complicated by arteritis, as well as several other conditions including Hyponatremia, hypochloremia, and hypocalcemia due to insufficient intake, Chronic Suppurative Otitis Media (CSOM) and Typhoid Fever. Results: The patient was diagnosed with aspiration pneumonia, cryptococcal meningitis, multiresistant tuberculous meningitis, as well as other conditions such as hypernatremia, hypokalemia, hypocalcemia, chronic suppurative otitis media, and typhoid fever. Despite treatment, the patient's condition worsened, leading to respiratory failure and death from aspiration pneumonia. Conclusions: This case report highlights the diagnostic and therapeutic challenges in managing concurrent cryptococcal meningitis and multiresistant tuberculous meningitis. This emphasizes the importance of a comprehensive approach in diagnosis and management in patients with complex concurrent infections, even without HIV. This case also emphasizes the need for further research and improved strategies for managing rare and complex infections such as this.
Nutritional, Physical Activity, and Mental Health Interventions to Enhance Cardiovascular Health: A Scoping Review Elsadai, Elsadai; Trisyani, Yanny; Nuraeni, Aan
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.553

Abstract

Cardiovascular disease (CVD) remains the leading cause of mortality globally and in Indonesia, with rising incidence among younger populations due to modifiable risk factors such as poor diet, physical inactivity, and mental health issues. These lifestyle-related factors are increasingly prevalent, yet interventions addressing them are varied and dispersed across the literature. To explore recent nutritional, physical activity, and mental health interventions for the prevention of cardiovascular disease. This study used a scoping review design. Articles were obtained from six databases, EBSCO-host, CINAHL, PubMed, ScienceDirect, Scopus, Taylor and Francis, and Google Scholar, with the major keywords “dietary”, “physical activity”, “mental health”, “cardiovascular disease”, “prevention”. Inclusion criteria included original studies, in English, published between 2015–2025, and the population reviewed was Adults / General population / High-risk individuals (e.g., aged >30, person with history of CVD). Data extraction followed the PRISMA-ScR guidelines. Twelve articles meeting the inclusion criteria showed intervention of prevention of cardiovascular disease. Physical activities such as walking, yoga, and exercise programs effectively improve cardiovascular health and physical fitness. Nutritional approaches like the Mediterranean diet help reduce cholesterol levels and blood pressure. Mental health practices, including meditation and stress management, contribute to lowering anxiety and blood pressure.  This review emphasizes that integrating regular physical activity, a nutritious diet, and mental health support is essential for effectively preventing cardiovascular disease, with personalized approaches playing a key role in helping individuals maintain these healthy habits.