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Peran Insulin-like Growth Factor-1 (IGF-1) terhadap Penyakit Kardiovaskular Zubadi, Fitrianisa Faradina; Harahap, Herpan; Saputri, Legis; Arina Windri Rivarti
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.5379

Abstract

Insulin-like growth factor 1 (IGF-1) is a major regulator of somatic growth that mediates the effects of growth hormone (GH). IGF-1 receptors are expressed by three major cells involved in the pathogenesis of atherosclerosis, namely endothelial cells, macrophages, and smooth muscle cells. Recent in vivo studies have discussed the effects of IGF-1 on the pathogenesis of atherosclerosis. This paper will discuss the relationship and role of IGF-1 in heart and blood vessel disease.
PEMBERDAYAAN MASYARAKAT PESISIR MELALUI KONSERVASI TERUMBU KARANG DI DUSUN NIPAH, DESA MALAKA, KABUPATEN LOMBOK UTARA Jurnal Wicara; Larasati, Septiani; Putra, Desta; Julianingsih, Laili; Damayani, Dian; Choneri, Shelina; Nadira; Rohmatin, Khairina; Novita, Baiq; Alvira, Dea; Rahman, Aldena; Harahap, Herpan
Jurnal Wicara Vol 3 No 5 (2025): Jurnal Wicara Desa
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/spqgdt86

Abstract

The Nipah coastline in Nipah Hamlet, Malaka Village, North Lombok Regency has experienced coral reef damage that has impacted fish catches and community welfare. This community service activity aims to empower coastal communities through coral reef conservation to support the sustainability of marine ecosystems. The method used is the Asset-Based Community Development (ABCD) approach, which includes the stages of discovery, dream, design, define, and destiny. The results of the activity include an increase in coral reef conservation media, specifically spider media from 70 to 80 units and table media from 5 to 6 units. Coral reef conservation is carried out through long-term monitoring of the survival and diversity of organisms to restore the functions of damaged marine ecosystems and support coastal stability. Community empowerment in coral reef conservation at Nipah Beach has significant social and economic impacts, including increased fish populations that boost local fishermen's catches and promote the development of marine tourism, creating economic opportunities for coastal merchants. while active community involvement strengthens social capital and community capacity in sustainable marine resource management, making the synergy between environmental conservation and economic well-being a crucial foundation for the sustainability of conservation programs in the area. Coral growth monitoring is planned three months later since the planting was recently completed. In conclusion, these initial coral reef conservation activities are an important step in supporting the achievement of SDG Goal 14: Life Below Water.