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All Journal JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Journal of Innovative and Creativity International Journal of Contemporary Sciences (IJCS)
Rosanti, Afi Sania
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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FORMULATION AND STABILITY TESTING OF SOLID SOAP CONTAINING A COMBINATION OF PURE HONEY (MEL DEPURATUM) AND RED DRAGON FRUIT PEEL EXTRACT (HYLOCEREUS COSTARICENSIS) Zahwa, Nabilla; Rosanti, Afi Sania; Dwiningrum, Riza; Daskar, Annajim
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4247

Abstract

Solid soap is a body cleansing preparation commonly used to maintain skin health, especially for the purpose of perfuming, improving body odor. Some previous studies have developed solid soap formulations with red dragon fruit peel extract, but no studies have combined it with other natural ingredients that are humectant and antibacterial such as pure honey. The purpose of this study was to determine the concentration of formulations that provide the most effective stability results for solid bath soap preparations of dragon fruit peel extract combined with pure honey. The method used in this research is experimental, making simplisia of red dragon fruit skin then extracted with 70% ethanol solvent. Solid bath soap was formulated with different concentrations of pure honey and red dragon fruit peel extract in each formula. In this study, the results of formulation I did not meet the requirements on hardness and foam stability. Formulation II did not meet the requirements on pH, foam stability, and free fatty acids. Formulation III did not meet the requirements on pH, hardness, foam stability, and free fatty acids. Based on the hedonic test, formulation II was most liked by panelists on color, aroma, and shape. So it can be concluded that the characteristics of the three formulas differ based on the concentration levels of honey and extracts used and the most effective stability results are found in formulation I.
FORMULATION OF VARIATIONS IN THE COMBINATION CONCENTRATIONS OF ROBUSTA COFFEE (Coffea canephora) POWDER AND TURMERIC RHIZOME EXTRACT (Curcuma longa L.) ON THE QUALITY OF BODY SCRUB PREPARATIONS Sumiyati; Rosanti, Afi Sania; Dwiningrum, Riza; Safutri, Wina
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4265

Abstract

Body scrub is a skincare product used to exfoliate dead skin cells and accelerate skin regeneration. Natural ingredients such as robusta coffee powder (Coffea canephora), which contains caffeine, act as a natural exfoliant, while turmeric rhizome extract (Curcuma longa L.), which contains curcuminoids, functions as an antioxidant and skin brightener. This study aimed to formulate a body scrub using varying concentrations of robusta coffee powder and turmeric extract, and to evaluate its physical properties, stability, and consumer preference. An experimental method was used with five formulations: F1 (10% coffee), F2 (10% turmeric), F3 (7%:3%), F4 (8%:2%), and F5 (9%:1%). Evaluations included organoleptic testing, homogeneity, pH, spreadability, adhesion, cream type, viscosity, stability, and hedonic testing. Results showed that all formulations met the criteria for good physical quality. Based on hedonic tests, F1 was the most preferred in terms of color, while F4 was most favored for aroma and texture, making it the best formulation with no significant difference (p>0.05). This study supports the development of natural body scrubs using local ingredients that are safe and effective.
Optimization of Teak Leaf Extract (Tectona grandis L.F) and Carbopol in Hair Dye Formulation Using Factorial Design Method halimah, Sofiati; Rosanti, Afi Sania; Dwiningrum, Riza; Pratiwi, Mida
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4283

Abstract

Cosmetics are preparations intended for use on the external parts of the human body, and one commonly used type is hair dye. However, many hair dye products on the market still rely on synthetic dyes, which may pose health risks such as irritation or internal organ damage if used long-term. To reduce these risks, the use of natural dyes has become an increasingly popular alternative, especially due to their content of anthocyanins that can provide natural color. One such natural ingredient is teak leaves (Tectona grandis L.F), which are rich in anthocyanin pigments and other bioactive compounds. This study aims to determine the optimal hair dye gel formulation using a combination of teak leaf extract and Carbopol, utilizing the Factorial Design method. The research was conducted observationally by preparing several formulas with varying concentrations, followed by evaluating the physical properties of each formulation, including organoleptic tests, pH, homogeneity, spreadability, adhesion, viscosity, and protective ability. The results indicated that the optimal formula consisted of 15% teak leaf extract and 2% Carbopol, showing a pH of 6.1±0.80, adhesion time of 7.74±2.41 seconds, spreadability of 6.43±0.60 cm, and viscosity of 34,000±12,124 cps. The resulting gel appeared stable, homogeneous, and capable of protecting the scalp. Therefore, the combination of teak leaf extract and Carbopol can be formulated into a natural hair dye cosmetic product that meets quality standards, offers good stability, and is safe for use.
The Caffeine Analysis in Tea Bag and Robusta Coffee Using UHPLC Methods Sutomo, Ahmad; Ridwan, Muhammad; Suswidiantoro, Vicko; Pisacha, Iga Mayola; Daskar, Annajim; Rosanti, Afi Sania
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 12 (2024): October 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i12.12040

Abstract

Caffeine, a natural psychostimulant, enhances arousal by inhibiting the effects of adenosine on the dopamine pathway. This study aimed to analyze and compare caffeine concentrations in seven robusta coffee samples (coded RC) and five black tea bags (coded BT) using both qualitative and quantitative methods. Qualitative tests employed Dragendorff reagents for coffee and Parry reagents for tea, confirming caffeine presence through colorimetric changes. Quantitative analysis utilized reverse-phase UHPLC, with a mobile phase of aquabidestilata and methanol (60:40), a C18 stationary phase at 40°C, and detection at 272 nm. Validation parameters demonstrated strong performance, with an RSD of 0.573%, a linear correlation coefficient of 0.998 for concentrations between 100–250 ppm, a LoD of 1.02 ppm, a LoQ of 3.10 ppm, and 99.88% accuracy. Results showed robusta coffee sample RC3 contained the highest caffeine concentration at 26.00 mg/serving, while black tea sample BTB3 exhibited 2.44 mg/serving. Despite higher caffeine levels in robusta coffee compared to black tea, both remained below the SNI threshold of 50 mg/serving, confirming their safety for consumption.
Formulasi Dan Uji Aktivitas Antioksidan Sediaan Sabun Cair Ekstrak Daun Pepaya (Carica Papaya L.) Menggunakan Metode Dpph (2,2-Diphenyl-1-Picrylhydrazyl) Novita, Riska Reza; Daskar, Annajim; Suswidiantoro, Vicko; Rosanti, Afi Sania
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3487

Abstract

Daun pepaya (Carica papaya L.) mengandung senyawa aktif seperti flavonoid, alkaloid, tanin, dan vitamin C yang berfungsi sebagai antioksidan. Antioksidan sendiri berperan penting dalam menetralisir radikal bebas yang dapat merusak jaringan kulit serta dapat mempercepat proses penuaan. Dalam sediaan sabun cair, penambahan bahan alami yang bersifat antioksidan tidak hanya berfungsi sebagai pembersih, tetapi juga dapat memberikan manfaat protektif terhadap kulit dari efek buruk lingkungan, seperti polusi dan paparan sinar UV. Oleh karena itu, formulasi sabun cair yang mengandung ekstrak daun pepaya (Carica papaya L.) berpotensi sebagai sediaan fungsional yang mendukung kesehatan kulit sekaligus memberikan efek perawatan. Tujuan dari penelitian ini adalah untuk mengetahui formula sabun cair ekstrak daun pepaya yang memiliki aktivitas antioksidan terbaik berdasarkan nilai IC₅₀ menggunakan metode DPPH. Penelitian eksperimental ini memformulasikan sediaan sabun cair dengan variasi konsentrasi ekstrak daun pepaya sebesar 6%, 8%, 10%, dan 12%. Evaluasi dilakukan terhadap parameter organoleptik, pH, tinggi busa, viskositas, homogenitas, stabilitas, dan aktivitas antioksidan menggunakan metode DPPH, yang dibaca pada spektrofotometer UV-Vis. Formula dengan konsentrasi ekstrak 10% (F3) menunjukkan nilai IC₅₀ sebesar 103,89 ppm, yang tergolong aktivitas antioksidan sedang. Formula F3 dinyatakan sebagai formula terbaik berdasarkan aktivitas antioksidannya karena memiliki nilai IC₅₀ yang paling rendah, sehingga menunjukkan potensi antioksidan yang lebih kuat dibandingkan dengan formula lainnya. Kata kunci : Daun pepaya, sabun cair, antioksidan, DPPH, IC₅₀.   ABSTRACT Papaya leaf (Carica papaya L.) contain active compounds such as flavonoids, alkaloids, tannins, and vitamin C, which act as antioxidants. Antioxidants play an important role in neutralizing free radicals that can damage skin tissues and accelerate the aging process. In liquid soap formulations, the addition of natural antioxidant ingredients not only functions as a cleanser but also provides protective benefits to the skin against harmful environmental effects such as pollution and UV exposure. Therefore, liquid soap formulated with papaya leaf extract (Carica papaya L.) has the potential to serve as a functional product that supports skin health while offering skincare benefits. This study aimed to determine the best liquid soap formulation containing papaya leaf extract with the highest antioxidant activity based on the IC₅₀ value using the DPPH method. This experimental research formulated liquid soap with varying concentrations of papaya leaf extract at 6%, 8%, 10%, and 12%. Evaluations were carried out on organoleptic parameters, pH, foam height, viscosity, homogeneity, stability, and antioxidant activity using the DPPH method, measured with a UV-Vis spectrophotometer. The formulation with 10% extract concentration (F3) showed an IC₅₀ value of 103.89 ppm, classified as moderate antioxidant activity. F3 was identified as the best formulation based on its antioxidant activity, as it had the lowest IC₅₀ value, indicating stronger antioxidant potential compared to the other formulations.
Pengaruh Variasi Konsentrasi Kombinasi Ekstrak Buah Tomat (Solanum Lycopersicum L) Dan Madu (Mel depuratum) Terhadap Mutu Dan Stabilitas Sediaan Eye Cream Kartika, Jelita; Rosanti, Afi Sania; Daskar, Annajim; Suswidiantoro, Vicko
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3565

Abstract

Lingkaran hitam di bawah mata (hiperpigmentasi periorbital) merupakan masalah kulit yang umum dan sering diatasi dengan penggunaan eye cream. Bahan alami seperti buah tomat (Solanum lycopersicum L) yang kaya likopen dan vitamin c, serta madu (Mel depuratum) yang memiliki sifat humektan dan antioksidan, berpotensi menjadi kombinasi bahan aktif dalam formulasi eye cream yang efektif dan aman. Penelitian ini bertujuan memformulasikan eye cream dengan variasi konsentrasi kombinasi ekstrak tomat dan madu menggunakan metode Simplex Lattice Design (SLD), serta menentukan formula optimal berdasarkan mutu fisik dan stabilitas sediaan. Variabel yang diuji meliputi organoleptis, homogenitas, pH, daya lekat, daya sebar, viskositas dan stabilitas. Penelitian ini di lakukan di Laboratorium Farmasetika Universitas Aisyah Pringsewu dan laboratorium Bahan Alam Universitas Aisyah Pringsewu pada bulan Juli-Agustus 2025. Hasil analisis pada penelitian ini membuat 6 fomulasi eye cream dengan konsentrasi ekstrak tomat dan madu 2,5:4,5 (F1), 2:5 (F2), 1:6 (F3), 1,5:5,5 (F4) dan 3:4 (F5). Dari penelitian ini dapat disimpulkan bahwa formula optimal eye cream ekstrak tomat (Solanum lycoperscum L) dan madu (Mel depuratum) dapat diperoleh ekstrak tomat 1% dan madu 6% menggunakan metode SLD dengan nilai optimal.
Formulasi Sediaan Lotion Fraksi Etanol Kulit Coklat (Theobroma cacao L) Sebagai Antioksidan Humayroh, Suci; Rosanti, Afi Sania; Putri, Diah Kartika; Suswidiantoro, Vicko
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3629

Abstract

ABSTRACT Kulit salah satu organ terluar tubuh yang rentan mengalami kerusakan akibat paparan radikal bebas dari sinar ultraviolet dan faktor lingkungan lainnya. Kondisi tersebut dapat memicu kerusakan kulit, penuaan dini hingga kanker kulit, sehingga diperlukan perlindungan kulit dengan senyawa antioksidan. Kulit coklat (Theobroma cacao L) diketahui mengandung flavonoid dan polifenol yang berpotensi sebagai antioksidan alami. Penelitian ini bertujuan untuk memformulasikan sediaan lotion berbasis fraksi etanol kulit coklat serta menilai sifat fisik dan aktivitas antioksidan berdasarkan nilai IC50. Ekstraksi dilakukan melalui metode maserasi menggunakan etanol 96%, dan fraksinasi, kemudian diformulasikan dalam tiga konsentrasi, yaitu F1(0,05gr), F2(0,1gr), dan F3(0,2gr). Evaluasi mutu fisik mencakup uji organoleptik, homogenitas, pH, viskositas, daya sebar, daya lekat, dan daya proteksi, sedangkan uji aktivitas antioksidan menggunakan metode DPPH. Hasil sediaan lotion fraksi etanol kulit coklat memenuhi semua syarat mutu fisik yang tidak memenuhi syarat mutu fisik pada uji proteksi F1&2. Hasil aktivitas antioksidan sediaan lotion fraksi etanol F1 sedang (126,6 ppm), F2 sangat kuat (48,55 ppm), dan F3 sangat kuat (36,67 ppm). Kesimpulan pada penelitian ini menunjukkan hasil bahwa F3 memenuhi semua kriteria mutu fisik sediaan lotion dan memiliki kandungan antioksidan terbaik, Penelitian ini juga menjadi Upaya pemanfaatan limbah kulit coklat (Theobroma cacao L) sebagai bahan baku kosmetik yang ramah lingkungan sehingga dapat menjadi dasar untuk pengembangan produk kosmetik herbal yang efektif dan aman. Kata Kunci: Antioksidan, DPPH, IC50, kulit coklat, lotion ABSTRACT The skin is one of the outermost organs of the body that is vulnerable to damage caused by free radicals from ultraviolet radiation and other environmental factors. Such conditions may trigger skin damage, premature aging, and even skin cancer, thus requiring protection with antioxidant compounds. Cocoa shell (Theobroma cacao L.) contains flavonoids and polyphenols that have potential as natural antioxidants. This study aimed to formulate a lotion preparation based on the ethanol fraction of cocoa shell and to evaluate its physical properties and antioxidant activity based on IC50 values. Extraction was carried out by maceration using 96% ethanol, followed by fractionation, and the fraction was then formulated into three concentrations: F1(0.05gr), F2(0.1gr), and F3(0.2gr). Physical evaluations included organoleptic test, homogeneity, pH, viscosity, spreadability, adhesion, and protection, while antioxidant activity was tested using the DPPH method. The results showed that all lotion formulations met physical quality requirements, except that F1 and F2 did not meet the criteria in the protection test. Antioxidant activity of the ethanol fraction lotion was classified as moderate for F1 (126.6 ppm), and very strong for F2 (48.55 ppm) and F3 (36.67 ppm). In conclusion, F3 fulfilled all physical requirements and had the best antioxidant activity. This study also represents an effort to utilize cocoa shell waste (Theobroma cacao L.) as an eco-friendly cosmetic ingredient and a foundation for the development of safe and effective herbal cosmetic products. Keywords: Antioxidant, DPPH, IC50, cocoa shell, lotion
Uji Aktivitas Daya Hambat Kombinasi Ekstrak Daun Jambu Biji (Psidium guajava L.) Dan Daun Pepaya (Carica papaya L.) Terhadap Pertumbuhan Bakteri Staphylococus aureus Rahmawati, Fani; Dwiningrum, Riza; Rosanti, Afi Sania; Safutri, Wina
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Staphylococcus aureus merupakan bakteri patogen penyebab berbagai infeksi, yang saat ini menunjukkan peningkatan resistensi terhadap beberapa antibiotik. Salah satu upaya untuk mengatasi resistensi ini adalah pemanfaatan bahan alam yang memiliki potensi antibakteri, seperti daun pepaya (Carica papaya L.) dan daun jambu biji (Psidium guajava L.). Penelitian ini bertujuan untuk mengetahui aktivitas daya hambat kombinasi ekstrak etanol daun pepaya dan daun jambu biji terhadap pertumbuhan Staphylococcus aureus. Penelitian dilakukan secara eksperimental di laboratorium menggunakan metode difusi cakram dengan variasi konsentrasi kombinasi ekstrak 25% dan 30% pada perbandingan (1:1), (1:2),  (2:1), dan (3:2). Parameter yang diamati adalah diameter zona hambat pertumbuhan bakteri. Hasil diameter zona hambat penelitian ini yaitu kontrol positif (21,27±1,07 mm) kategori sangat kuat, perlakuan 1 dengan perbandingan 1:1 (9,41±1,10 mm) kategori sedang, perlakuan 2 dengan perbandingan 1:2 (9,80±1,16mm) kategori sedang, perlakuan 3 dengan perbandingan 2:1 (8,94±2,21 mm) kategori sedang, perlakuan 4 dengan perbandingan 3:2 (8,55±0,97 mm) kategori sedang. Analisis data menggunakan uji ANOVA menghasilkan nilai signifikansi p=0.835 (p < 0,05) yang menunjukkan tidan ada perbedaan bermakna.  
Co-Authors Daskar, Annajim halimah, Sofiati Humayroh, Suci Kartika, Jelita Mida Pratiwi Muhammad Ridwan Novita, Riska Reza Pisacha, Iga Mayola Putri, Diah Kartika Rahmawati, Fani Riza Dwiningrum, Riza Sumiyati Suswidiantoro, Vicko Sutomo, Ahmad Wina Safutri Zahwa, Nabilla