Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran
Herbert Situmorang Herbert Situmorang
Department Of Obstetrics And Gynecology Faculty Of Medicine Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Unmasking the Culprit: Successful Restoration of Menstrual Function in a Case of Secondary Amenorrhea Due to Tuberculous Endometritis Mimicking Polycystic Ovary Syndrome Riyan Hari Kurniawan; Muhammad Syauqi Mirza; Ilham Utama Surya; Muhammad Dwi Priangga; Cepi Teguh Pramayadi; Herbert Situmorang; Eka Rusdianto Gunardi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1390

Abstract

Background: Secondary amenorrhea presents a significant diagnostic challenge in gynecology. While Polycystic Ovary Syndrome (PCOS) is a common cause, rare etiologies like tuberculous endometritis can be overlooked, especially in patients with features suggestive of PCOS. This phenomenon, known as diagnostic overshadowing, can lead to delayed diagnosis and irreversible reproductive consequences. Case presentation: A 35-year-old nulligravid woman with a diagnosis of Class I Obesity presented with a five-year history of secondary amenorrhea and a desire for fertility. Her clinical and initial ultrasonographic findings were suggestive of PCOS. However, persistent amenorrhea despite hormonal therapy prompted further investigation. Hysteroscopy revealed a fibrotic uterine cavity with micropolyps, and subsequent endometrial biopsy with histopathology, polymerase chain reaction (PCR), and culture confirmed a diagnosis of tuberculous endometritis. The patient was successfully treated with a six-month anti-tuberculosis regimen, cyclical progestin therapy, and a structured lifestyle modification program. Following treatment, she experienced a significant weight loss, resumption of regular menstrual cycles, and marked improvement in endometrial and ovarian ultrasound parameters. Conclusion: This case underscores the critical importance of a comprehensive diagnostic evaluation for secondary amenorrhea, including endometrial sampling, even when a common diagnosis like PCOS is suspected. It highlights the potential for tuberculous endometritis to mimic PCOS and demonstrates the efficacy of a multidisciplinary approach in restoring menstrual and potentially reproductive function. Clinicians in tuberculosis-endemic regions must maintain a high index of suspicion for this insidious pathology to prevent long-term morbidity.
Co-Authors -, Bintari Puspitasari Abidin, Finekri Achmad K. Harzif Alexander Mukti Andon Hestiantoro Ardhana Iswari, Wulan Biran Affandi Biran Affandi Budi Wiweko Caroline G. Puspita Cepi T. Pramayadi Cepi Teguh Pramayadi Darus, Febriansyah Eka R Gunardi Eka R Gunardi Eka R. Gunardi Eka Rusdianto Gunardi Gita Pratama Ilham Utama Surya Ivanna T Setijanto J Endjun, Judi Kanadi Sumapradja Kemal, Achmad Legiantuko, Ario Lestari, Renny Muhammad D. Priangga Muhammad Dwi Priangga Muhammad Syauqi Mirza Raden Muharam Natadisastra Radityo, Dimas Raymond R. Tjandrawinata Raymond Surya Ribkhi A. Putri Riyan H. Kurniawan Riyan Hari Kurniawan Santana, Sanny Satria, Luky Setijanto, Ivanna T Tantri Hellyanti Taufik Akbar Tritama, Duta A Uli Pardede, Tiarma