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Hubungan Efek Samping Kemoterapi dengan Kualitas Hidup Pasien Kanker Payudara di Rumah Sakit Umum Cut Meutia Kabupaten Aceh Utara Nasywa Fawwaza; Adi Rizka; Mulyati Sri Rahayu
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 3 (2025): Desember : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i3.6529

Abstract

Breast cancer, which typically develops from epithelial cells in the breast ducts or lobes, is a highly prevalent cancer among women worldwide. This disease requires intensive treatment, including chemotherapy, which plays a crucial role in stopping or slowing the growth of cancer cells. Although chemotherapy is effective, it often causes significant side effects, such as nausea, vomiting, fatigue, hair loss, and a weakened immune system. These side effects have the potential to reduce a patient's overall quality of life, both physically, psychologically, and socially. Therefore, this study aims to establish a link between the occurrence of chemotherapy-related side effects and the quality of life of breast cancer patients undergoing treatment at Cut Meutia General Hospital in North Aceh. This study used an observational cross-sectional approach, involving 50 patients undergoing chemotherapy between October and January. Participants were selected purposively to ensure compliance with the study criteria. Data collection was conducted using the Indonesian version of the WHOQOL-BREF, a valid and reliable instrument for measuring quality of life in various domains, including physical, psychological, social, and environmental. Data analysis using the chi-square test revealed a significant relationship between chemotherapy side effects and decreased quality of life in patients with a p-value of 0.002. The results of this study emphasize the need for an adaptive and comprehensive side effect management strategy so that patients can undergo therapy more comfortably and maintain an optimal quality of life during the treatment process. A multidisciplinary approach involving medical personnel, psychologists, and families is highly recommended to support the physical and mental condition of patients during chemotherapy.
DIAGNOSIS DAN TATA LAKSANA CARPAL TUNNEL SYNDROME: SEBUAH TINJAUAN LITERATUR TERKINI Nasywa Fawwaza
Integrative Perspectives of Social and Science Journal Vol. 3 No. 01 Januari (2026): Integrative Perspectives of Social and Science Journal
Publisher : PT Wahana Global Education

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Carpal Tunnel Syndrome (CTS) merupakan neuropati kompresi simtomatik pada nervus medianus di dalam terowongan karpal yang ditandai dengan peningkatan tekanan intrakarpal dan penurunan fungsi saraf. Kondisi ini merupakan gangguan tangan dan lengan yang umum dijumpai, terutama pada wanita di atas usia 30 tahun, dengan etiologi yang meliputi faktor hereditas, trauma, gerakan repetitif pada pekerjaan, hingga kondisi metabolik seperti diabetes melitus. Manifestasi klinis utama berupa parestesia, nyeri nokturnal, hingga atrofi otot thenar pada stadium lanjut. Diagnosis ditegakkan melalui anamnesis, pemeriksaan fisik provokatif seperti tes Phalen dan tanda Tinel, serta didukung oleh pemeriksaan elektrodiagnostik berupa Nerve Conduction Studies (NCS). Tata laksana CTS mencakup pendekatan konservatif melalui splinting pergelangan tangan, fisioterapi, dan injeksi kortikosteroid lokal, sementara intervensi bedah dekompresi diindikasikan pada kasus yang refrakter terhadap terapi konservatif atau yang menunjukkan defisit motorik berat. Secara keseluruhan, prognosis CTS umumnya baik dengan penanganan yang tepat, meskipun risiko rekurensi tetap perlu diwaspadai.