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All Journal Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Riseta Naturafarm
Putri, Nur Arinda
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Public Health Social Sciences

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The Potential of Carbon Monoxide (CO) as a Therapeutic Agent in Cancer Treatment: A Literature Review: Potensi Karbon Monoksida Sebagai Agen Terapeutik Dalam Pengobatan Kanker: Tinjauan Literatur Samsul, Erwin; Dewi, Jingga Apriani Jevita; Agustina, Inayah Yuli; Atmadja, Meilda Keysia Angelica; Rombe, Irene Aliet; Nabilah, Cindy; Sari, Mila Kansia; Putri, Nur Arinda
Jurnal Riseta Naturafarm Vol. 2 No. 2 (2025): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v2i2.5664

Abstract

Background: Carbon monoxide (CO) has shown potential as an anti-cancer therapy, rather than simply functioning as a toxin. Recent research indicates that carbon monoxide (CO), which is a carbon-based nanoparticle, can target cancer cells and induce apoptosis. CO shows promising cytotoxic activity against cancer cell lines as one of the therapies in cancer treatment. The purpose of this article is to present a concise look at the physiological and biochemical traits of CO and the mechanism of its therapeutic potential in the treatment of cancer Methods: This study is a literature review. The database used in the search for this article using google scholar, pubmed, and elsevier. the data collection process uses the keywords “Carbon Monoxide, cancer, anti- cancer therapy” which are taken from the results of research that has been done previously both from within and outside the country. The results of this research article review are Carbon Monoxide (CO) not only has a toxic effect but also has a cytotoxic effect on cancer cells. In cancer cells treated with CO, there was a significant reduction in Akt (protein kinase B) phosphorylation, a key factor in cancer neovascularization, by 30-50%.
PASCIDA: Program Peningkatan Pengetahuan Siswa tentang Pencegahan ISPA dan Diare di Desa Muara Bengkal Ilir Aprilia, Dinda Ayu; Maharani, Ersa Sabrina; Rahmanisa, Fatika; Putri, Haniva Yudita; Jevita Dewi, Jingga Apriani; Farizy, Muhammad Dziban; Putri, Nur Arinda; Isnuwardana, Ronny
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 6 No. 4 (2025): Edisi Oktober - Desember
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v6i4.6951

Abstract

PASCIDA (Pahlawan Sehat Cegah ISPA dan Diare) adalah program pengabdian masyarakat yang bertujuan meningkatkan pengetahuan siswa tentang pencegahan Infeksi Saluran Pernapasan Akut (ISPA) dan diare di Desa Muara Bengkal Ilir. Program ini menggunakan metode interaktif, yaitu penyuluhan kesehatan dan permainan edukasi digital berbasis “Kahoot!” kepada siswa di tingkat SD, SMP, dan SMA/SMK. Peningkatan pengetahuan diukur melalui pretest dan posttest. Hasilnya menunjukkan adanya peningkatan signifikan pada nilai rata-rata posttest di seluruh jenjang pendidikan (p<0,001, diuji dengan tes Wilcoxon), yang membuktikan efektivitas intervensi. Program ini tidak hanya berhasil meningkatkan pengetahuan, tetapi juga memberdayakan siswa sebagai agen perubahan kesehatan di lingkungan mereka. Keberlanjutan program dijamin dengan penempatan poster dan infografis edukatif di sekolah.
Co-Authors Agustina, Inayah Yuli Aprilia, Dinda Ayu Atmadja, Meilda Keysia Angelica Dewi, Jingga Apriani Jevita Erwin Samsul Farizy, Muhammad Dziban Jevita Dewi, Jingga Apriani Maharani, Ersa Sabrina Nabilah, Cindy Putri, Haniva Yudita Rahmanisa, Fatika Rombe, Irene Aliet Ronny Isnuwardana Sari, Mila Kansia