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All Journal Proceeding of Mulawarman Pharmaceuticals Conferences

Erwin Samsul

Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis"?, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Author-ID : 5589902

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 8 Documents Claim Missing Document

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Articles

Efektivitas Serum Lidah Buaya (Aloe vera) terhadap Peningkatan Laju Pertumbuhan Rambut dan Sun Protection Bella Sasmiyandri; Erwin Samsul; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Aloe vera has the potential to increase hair growth rate and sun protection so it is suitable to be formulated in serum. The purpose of this study was to produce a serum formula that meets the standards and produce a serum that has an effect in increasing hair growth rate and sun protection.This study was conducted to make aloe vera serum formula in third variation of the active substance and do a physical evaluation. Data from the physical evaluation test results and for hair growth and sun protection using analyzed statistic. The test results aloe vera serum organopetic clear white with a thick consistency and oleum rosae fragrance. Aloe vera serum have a homogenity dispersion with a viscosity of between 0.023 to 0.058 (Pa.s), the pH value between 5.7 to 6.1 and the spreadability between 6-7 cm. Aloe vera serum is stable for 3 weeks storage at room temperature. Aloe vera serum seen qualitative and quantitative has the effect of hair growth that is equivalent to the positive control (minoxidil) in the treatment for 21 days, and sun protection don’t have effect.

Pengaruh Berbagai Metode Ekstraksi dari Ekstrak Etanol Umbi Bawang Tiwai (Eleutherine americana Merr) terhadap Rendemen Ekstrak dan Profil Kromatografi Lapis Tipis Ayida Mawarda; Erwin Samsul; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The bulb of Eleutherine americana Merr is a typical Kalimantan plant that has many medicinal properties. Many studies have been carried out with various extraction methods used to determine the compounds contained in the bulb of Eleutherine americana Merr. This study aims to determine the effect of the method and the extraction time on the yield value and thin layer chromatography profile (TLC) of the bulb of Eleutherine americana Merr extract. The extraction method uses 96% ethanol solvent using the maceration method for 2 weeks and ultrasonic bath method with time variables of 10, 20 and 30 minutes. The yield of maceration extract was 12% and the ultrasonic bath method was 12.5%, 17.5%, and 15% (10, 20, 30 minutes). In the TLC test there were no differences in the spot patterns of the two extraction methods. So it can be concluded that the extraction method affects the yield of extract but does not affect the extract compound content seen from the TLC spot pattern.

Analisis Perubahan Kadar Sianida dan Aktivitas Sitotoksik pada Umbi Singkong Segar yang Diolah Menjadi Tape: Analysis of Changes in Cyanide Levels and Cytotoxic Activity in Fresh Cassava Tubers Processed into Tape Rahmat Budiman; Laode Rijai; Erwin Samsul
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Cassava in Indonesia is the third staple food after rice and corn. In addition, cassava can also be used as a process for other food products such as cassava tape, cassava crackers, opak, getuk, tapioca flour and cassava ejects. Besides containing carbohydrates, cassava also contains cyanide which is a poisonous compound. Cyanide acid is able to cause respiratory distress to death by inhibiting the performance of the respiratory enzymes, causing disturbances in the respiratory system. This study aims to determine changes in cyanide levels and cytotoxic activity in cassava tuber preparations. Qualitative analysis was performed using FeCl3 and AgNO3 reagents, quantitative tests used argentometric titration method. Meanwhile, the cytotoxic test used the Brine Shrimp Lethality Test (BSLT) method. The cyanide content test results obtained in fresh cassava were 41,56 mg, which was categorized as quite toxic, the toxicity level of fresh cassava was classified as toxic, namely 505.82 ppm. Whereas on the processed tape, the test results showed negative results containing cyanide. Cassava tuber cytotoxic test is classified as non-toxic, which is equal to 4216.96 ppm.

Evaluasi Penggunaan Antibiotik Secara Kuantitatif dan Kualitatif Pada Pasien Bedah Digestif di RSUD Abdul Wahab Sjahranie Samarinda: Quantitative and Qualitative Evaluation of Antibiotic Use in Digestive Surgery Patients at Abdul Wahab Sjahranie Hospital Samarinda Enjelina Natasya Sihite; Adam M. Ramadhan; Erwin Samsul
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Antibiotics are drugs that are the most widely prescribed to treat bacterial infections. Prescription of high and not wise antibiotics has a detrimental impact: increasing antibiotic resistance. This study aimed to determine patient characteristics, quantity, and quality of antibiotic use in digestive surgery patients at Abdul Wahab Sjahranie Hospital Samarinda from January-December 2020. This study is a retrospective observational study with data collection techniques using the purposive sampling method. The results obtained 75 medical records, with the majority of the adults (26-45 years old) were 35 patients (48%), men were 45 patients (60%), length of stay 4-5 days were 30 patients (40%), private workers were 23 patients (30.7%), and type of disease appendicitis were 27 patients (36%). The most used antibiotic is ceftriaxone, which is 64.41 DDD/100 patient days, and antibiotics included in segment 90% were ceftriaxone and metronidazole. The quality of antibiotic use was 54.91% included in category 0 including ceftriaxone, metronidazole, cefpirom, and levofloxacin, category IIIB as 35.26% including ceftriaxone, metronidazole, cefpirom, and cefixime, category IIIA as 4.05% including ceftriaxone and metronidazole, the IVC category as 4.62% including ceftriaxone and cefixime, and IVA as 1.16% including metronidazole.

Pengaruh Trietanolamin pada Basis Krim Minyak dalam Air yang Berbahan Dasar Asam Stearat dan Setil Alkohol: Effect of Triethanolamine on Oil-in-Water Cream Base Based on Stearic Acid and Cetyl Alcohol Novita Sari; Erwin Samsul; Angga Cipta Narsa
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The cream is a semi-solid preparation with one or more ingredients dispersed in two types of emulsions, water-in-oil (W/O) and oil-in-water (O/W) type creams. Oil-in-water type cream has a high water content so that it can provide a hydration effect that can increase the penetration of the active substance. Triethanolamine in topical preparations is used as an emulsifier and alkalizing agent to form a homogeneous and stable cream. The purpose of this research was to determine the effect of triethanolamine on an oil-in-water cream base based on stearic acid and cetyl alcohol. Making the base is done by making preparations using four concentrations of triethanolamine 0.5% (F1), 1% (F2), 1.5% (F3), and 2% (F4). The cream base was then evaluated for its physical properties including organoleptic, homogeneity, pH, viscosity, spreadability, adhesion, and phase separation test. The results showed that in the organoleptic test cream bases were white, had a characteristic aroma with a semisolid form. The cream base has a homogeneity dispersion with an average pH between 6.53-7.29, viscosity between 3.5792396-3.8001904 (Pa.s), spreadability between 5.43-5.78 cm, and adhesion between 4.47-6.25 seconds. The cream base did not have phase separation and was stable in storage for 4 weeks at room temperature.

Kajian Interaksi Obat Pasien Gagal Ginjal Kronis Di Instalasi Rawat Inap Rumah Sakit Samarinda Medika Citra: Study of Drug Interaction of Patients with Chronic Kidney Failure at the Inpatient Installation of Samarinda Medika Citra Hospital Angelina Theodora Hanyaq; Adam M. Ramadhan; Erwin Samsul
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Patients with chronic kidney failure generally have comorbidities that cause the treatment of chronic kidney failure to be complex so that the number of drugs received by patients increases. The number of drugs consumed by the patient will increase the potential for drug interactions. The purpose of this study was to determine the characteristics, treatment patterns and potential drug interactions of patients with chronic kidney failure at Samarinda Medika Citra Hospital. The research method used is a non-experimental (observational) descriptive study with a retrospective approach. Data collection was carried out based on the medical record sheet of Chronic Kidney Failure patients in the inpatient room at Samarinda Medika Citra Hospital and obtained 59 patients. The results of the study of characteristic data based on age with the highest percentage in the elderly as much as 52.54%, based on gender, the highest percentage of sex was in the male sex, namely 50.85% and female as much as 49.15%. The most common comorbidities was anemia 50.84%. The most use of drug class is combination of 4 therapies with Antihypertensive + Supplement, Vitamin, Mineral + Antiulcer + Antiemetic group as much as 79.66%. The most common potential drug interactions found was the interaction of ranitidine with calos as much as 35.59% with minor severity.

Skrinning Fitokimia Ekstrak Etanol Kulit Pisang Kepok (Musa paradisiaca L.) dan Evaluasi Sediaan Krim Wajah: Phytochemical Screening of Kepok Banana Peel Ethanol Extract (Musa paradisiaca L.) and Its Face Cream Evaluation Ester Melenya Looys Nababan; Laode Rijai; Erwin Samsul
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v15i1.617

Formulasi Snack Bar Tinggi Kalsium Dari Tepung Limbah Cangkang Telur Sebagai Sumber Nutrisi Kalsium: Formulation of Snack Bar High Calcium From Egg Shell Waste Flour as a Source of Calcium Nutrients Yeni Fitri Handayani; Erwin Samsul; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 16 (2022): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v16i1.661

Osteoporosis merupakan kelainan pada tulang yang disebabkan oleh gangguan metabolisme dikarenakan ketidakmampuan tubuh untuk menyerap dan memanfaatkan zat-zat yang diperlukan dalam proses pematangan tulang. Salah satu upaya yang dapat dilakukan untuk mencegah osteoporosis adalah dengan mengkonsumsi makanan tinggi kalsium. Fungsi utama kalsium adalah mengisi kepadatan tulang. Cangkang telur dapat menjadi salah satu sumber nutrisi kalsium karena kandungan kalsiumnya yang cukup tinggi. Cangkang telur mengandung komponen kalsium karbonat 94%, kalium fosfat 1% dan magnesium karbonat 1%. Oleh karena itu, penelitian ini bertujuan untuk mengetahui kandungan kalsium dalam tepung cangkang telur serta memformulasikan tepung cangkang telur dalam suatu sediaan snack bar. Metode penelitian yang digunakan adalah eksperimental laboratorium yaitu pengukuran kadar kalsium menggunakan spektrofotometri serapan atom pada tepung cangkang telur serta memformulasikan tepung cangkang telur dalam bentuk sediaan snack bar dengan konsentrasi 3%, 6% dan 9%. Pengukuran kadar kalsium pada tepung cangkang telur didapatkan hasil yaitu 24,5%. Hasil pengukuran kadar kalsium pada snack bar dengan penambahan tepung cangkang telur 3%, 6% dan 9% yaitu 0,38%, 0,58% dan 0,69%. Maka, dapat disimpulkan bahwa cangkang telur memilki kandungan kalsium yang dapat dimanfaatkan untuk memenuhi kebutuhan kalsium sehari-hari.

Co-Authors Abdul Mun’im Adam M. Ramadhan Andreanus A. Soemardji Angelina Theodora Hanyaq Angga Cipta Narsa Ayida Mawarda Azminah Azminah Bella Sasmiyandri Enjelina Natasya Sihite Ester Melenya Looys Nababan Fajar Prasetya Gemini Alam Hadi Kuncoro Herlina Argantari Basuki Islamudin Ahmad Iswahyudi Iswahyudi Junaidin Junaidin Laode Rijai M. Arifuddin Niken Indriyanti Noor Linda Febrianie Novita Sari Rahmat Budiman Risna Agustina Rolan Rusli Siti Kusmardiyani Supriatno Salam Wisnu Cahyo Prabowo Yeni Fitri Handayani Yurika Sastyarina

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