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Intervensi Nutrisi Neuroprotektif terhadap Kadar GFAP dan Skor NIHSS pada Pasien Stroke Iskemik Diah Retno Wahyuningrum; Kalasta Ayunda Putri; Fitni Hidayati; Fathia Rahmadini
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6053

Abstract

Stroke is one of the leading causes of disability and mortality worldwide, with significant neurological and biochemical consequences. This study aimed to examine the effect of a neuroprotective nutritional intervention consisting of protein, phosphatidylcholine, phosphatidylserine, and inulin on glial fibrillary acidic protein (GFAP) levels and National Institutes of Health Stroke Scale (NIHSS) scores in acute ischemic stroke patients. The study employed a quasi-experimental design with a pretest-posttest control group, involving 18 patients divided equally into intervention and control groups. Data were collected at Dr. Kariadi General Hospital Semarang from January to February 2020, measuring serum GFAP levels using ELISA and assessing NIHSS scores before and after a seven-day intervention. The intervention group showed a significant decrease in GFAP levels and a more pronounced improvement in NIHSS scores compared to the control group. These findings suggest that the neuroprotective nutritional intervention may support both biochemical and clinical recovery in acute ischemic stroke patients. Implementing such nutritional strategies could complement standard care and enhance rehabilitation outcomes. Further research with larger sample sizes and longer follow-up is recommended to confirm these results and optimize the intervention protocol.  
System Quality and the Impact of the Use of the Flo Application on Free Association Within the Community in Padang City Using the Delone and Mclean Method Nailul Hikmi; Fitni Hidayati
Professional Evidence-based Research and Advances in Wellness and Treatment Vol. 2 No. 1 (2025): January, 2025
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/perawat.v2i1.113

Abstract

This study aims to analyze the quality of the Flo application system and its impact on social interactions and the prevalence of free social relationships in the city of Padang. Utilizing the DeLone and McLean model, the research focuses on three primary dimensions: system quality, information quality, and service quality. The findings suggest that higher quality in these areas significantly influences user satisfaction and engagement with the application. Moreover, the study explores the implications of increased social connectivity facilitated by the Flo application, examining both positive and negative effects on social behavior within the community. By collecting data through surveys and interviews, this research provides insights into the net benefits experienced by users, highlighting the potential for applications like Flo to reshape social norms and interactions. Recommendations for future development of the application are also discussed, emphasizing the need for features that promote positive social engagement while mitigating the risks of excessive free social interaction.