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All Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Cermin Dunia Kedokteran
Pradhea, Tifani Antonia
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Veterinary

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Gangguan Kognitif Pasca-Stroke – Tinjauan Sistematik: Analisis Pradhea, Tifani Antonia; Dwikarlina, Intan; Putra, Aulia Wiratama; Agustina, Lisa; Nardian, Derajat Fauzan
Cermin Dunia Kedokteran Vol 51 No 12 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i12.1239

Abstract

Introduction: The increasing number of stroke survivors was accompanied by an increase of cognitive impairment incidence as one of the post-stroke long-term consequences. Post-stroke cognitive impairment needs to be highlighted because of impact on reducing the quality of life, especially in the elderly. Methods: Literature was extensively searched across ScienceDirect, PubMed, Google Scholar, and Cochrane databases, using several predetermined keywords. Results and Discussion: Nine articles were analyzed. MMSE and MoCA assessments were used as parameters of post-stroke cognitive impairment. Most patients experience post-stroke cognitive impairment ranging from mild cognitive impairment to vascular dementia or other types of dementia. Risk factors include older age, female, lower and shorter education, location of lesions in the left hemisphere with involvement of certain brain structures, uncontrolled and fluctuating blood pressure, family history of stroke, comorbid diseases, as well as an individualistic social life. Conclusion: Stroke significantly increases the risk of cognitive impairment anddementia.
ANTIBACTERIAL POTENTIAL OF DAYAK ONION BULB EXTRACT (Eleutherine sp) AS A TREATMENT FOR ACNE VULGARIS: A LITERATURE REVIEW Pradhea, Tifani Antonia; Clarissa, Maria; Ridho, Muhammad; Aqsa, Sadilla; Sumarna, Dimas Aldianakhi; Assegaf, Syarifah Nurul Yanti Syahab; Zakiah, Mistika
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 4 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Acne vulgaris is a common skin disorder that can significantly affect quality of life. Although conventional antibiotic treatments are commonly used, herbal alternatives such as Eleutherine sp. (Dayak onion) bulb extract may offer therapeutic options for acne vulgaris. This study is a literature review that evaluates the antibacterial activity of Dayak onion bulb extract against bacteria that cause acne vulgaris. The search was conducted in the ScienceDirect, PubMed, Google Scholar, and Garuda databases, focusing on in vitro studies published in the last 10 years. Of the 8 articles analyzed, Dayak onion bulb extract was effective against Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acnes. The best antibacterial activity was obtained from extracts at high concentrations with several methods. Temperature and incubation duration also affected the results. Active compounds such as flavonoids, alkaloids, triterpenoids, steroids, and tannins contributed to the antibacterial effectiveness of this extract. Dayak onion bulb extract showed strong antibacterial effectiveness, making it a potential alternative for treating acne vulgaris. This extract as an additional therapy offers a safe option as a natural acne vulgaris treatment solution. Keywords: acne vulgaris, antibacterial, Eleutherine DOI : 10.35990/mk.v8n4.p446-457
Co-Authors Aqsa, Sadilla Assegaf, Syarifah Nurul Yanti Syahab Clarissa, Maria Dwikarlina, Intan Lisa Agustina, Lisa Mistika Zakiah Muhammad Ridho Nardian, Derajat Fauzan Putra, Aulia Wiratama Sumarna, Dimas Aldianakhi