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All Journal Medicosphere
Arbani, Rafi Auliya Arbani
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Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences

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Journal : Medicosphere

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Advancements in Understanding and Managing Parkinson's Disease: A Review of Recent Literature: A Literature Review Arbani, Rafi Auliya Arbani; Agastya, Wayan Dhea
Journal of Diverse Medical Research: Medicosphere Vol. 1 No. 1 (2024): J Divers Med Res 2024
Publisher : Faculty of Medical - UPN Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i1.34

Abstract

Background : Parkinson's Disease (PD) remains a complex and challenging condition, with ongoing research shedding light on its multifaceted nature. This review synthesizes recent findings on the genetic basis, autonomic dysfunction, lifestyle impacts, treatment advancements, and environmental considerations related to PD. By analyzing recent literature, this review aims to provide a comprehensive understanding of current trends and implications for future research and clinical practice. Methods : Literature searches were performed using databases including PubMed, Google Scholar, and SINTA with search terms such as "Parkinson’s" "Genetics" "lifestyle" and "environtment" Only systematic reviews of peer-reviewed articles, reports, and case studies were selected for inclusion. Discussion : The complexity of Parkinson's Disease (PD) and the necessity for a multidimensional approach to its understanding and management. Genetic research highlights opportunities for personalized medicine, while insights into autonomic dysfunction underscore the importance of comprehensive clinical evaluations. Lifestyle and environmental factors are increasingly recognized for their roles in PD prevention and management, advocating for a holistic approach. Advancements in treatment, including immunotherapy and neural grafting, provide hope for improved patient outcomes, though significant challenges remain in translating research into clinical practice. Conclusion : This review highlights the multifaceted nature of Parkinson's Disease, emphasizing the importance of integrating genetic, lifestyle, and environmental considerations into clinical practice. Recent advancements in understanding PD's underlying mechanisms and therapeutic innovations provide a foundation for improved management and prevention. A holistic and multidisciplinary approach is essential to enhance patient outcomes and address the challenges in diagnosing and treating this complex neurodegenerative disorder.
A Impact of Nuclear Radiation Exposure on Humans and Ecosystems: The Urgency of Iodine Pills in Emergency Management: A Literature Review Arbani, Rafi Auliya Arbani; Seliana, Irma
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 9 (2025): J Divers Med Res 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i9.151

Abstract

Background: Nuclear disasters and radioactive contamination pose severe health and environmental risks, with both immediate and long-term effects. Beyond acute radiation sickness, exposure increases the risk of genetic mutations, thyroid cancer, cardiovascular diseases, and immune suppression. Radioactive isotopes like iodine-131 (I-131), cesium-137 (Cs-137), and strontium-90 (Sr-90) persist in ecosystems, bioaccumulate, and contaminate food chains. Iodine pills play a crucial role in blocking I-131 absorption by the thyroid, reducing thyroid cancer risk. Objective: This study evaluates iodine prophylaxis as a primary intervention in nuclear disasters and examines the cascading effects of environmental contamination. Methods: A systematic review was conducted using PubMed, Scopus, and Google Scholar with keywords like “nuclear disaster,” “radiation exposure,” and “potassium iodide pills.” Seven Scopus-indexed journals were analyzed, focusing on nuclear disaster preparedness, radiation effects, and iodine pill efficacy. Discussion: Elevated I-131 levels heighten thyroid cancer risks, making iodine pills essential. Rapid distribution and public awareness are critical, especially for vulnerable populations. Contaminated food chains pose long-term health risks, necessitating decontamination, radiation surveillance, and bioremediation to mitigate environmental damage. Conclusion: Immediate iodine prophylaxis, environmental remediation, and continuous health monitoring are vital for reducing nuclear disaster risks. A multidisciplinary approach involving governments, healthcare professionals, and environmental experts is essential for effective preparedness and response strategies.
Co-Authors Irma Seliana Wayan Dhea Agastya