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All Journal JIPITI: Jurnal Pengabdian kepada Masyarakat Jurnal Sains dan Teknologi Pangan
Hikmah, Nurull
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Law, Crime, Criminology & Criminal Justice Other

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Edukasi Kesehatan tentang Tuberkulosis: Membangun Komitmen Masyarakat untuk Pengendalian TBC Kasmawati, Henny; Hikmah, Nurull; Trinovitasari, Nita; Jannah, Sitti Raodah Nurul; Malina, Rachma; Suryani, Suryani; Nuralifah, Nuralifah; Aswani, Aswani
JIPITI: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 4 (2025): November 2025 - JIPITI: Jurnal Pengabdian kepada Masyarakat
Publisher : PT. Technology Laboratories Indonesia (TechnoLabs)

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Abstract

Tuberculosis (TB) is an infectious disease that is still a global health problem, caused by the bacterium Mycobacterium tuberculosis, which is acid-resistant and mainly attacks the lungs, but can also attack other organs. This disease can affect people of all ages, including babies, children, adults, and the elderly. TB transmission occurs through the air from people who cough or sneeze, with the main factors affecting public health being environmental factors and behaviours, such as uncovered coughing and poor sanitation. TB cases in Southeast Sulawesi Province have shown a significant upward trend in recent years, with the incidence rate continuing to rise every year. The success of TB treatment is influenced by a variety of factors, including medication adherence, which is a major challenge to avoid the emergence of drug resistance, such as TB-MDR. The Government of Indonesia has issued policies and focuses on reducing TB incidence through education and socialisation to encourage active community involvement in TB control to achieve the national target by 2030.
POTENSI ANTIDEPRESAN EKSTRAK ETANOL BUAH KUNDUR (Benincasa hispida) SEBAGAI PANGAN FUNGSIONAL: EVALUASI IN VIVO PERILAKU DEPRESI DAN KOORDINASI MOTORIK Jatnika, Yayat; Nuralifah, Nuralifah; Malik, Fadhliyah; Parawansah, Parawansah; Hariana, Hariana; Hikmah, Nurull; Wahyuni, Wahyuni; FRISTIOHADY, ADRYAN
Jurnal Sains dan Teknologi Pangan Vol. 11 No. 2 (2026): Jurnal Sains dan Teknologi Pangan
Publisher : Jurusan Ilmu dan Teknologi Pangan Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63071/f9ahq066

Abstract

Tujuan penelitian ini untuk mengetahui pengaruh pemberian ekstrak etanol buah kundur (Benincasa hispida) terhadap perilaku depresi pada mencit jantan menggunakan metode Elevated Plus Maze (EPM) Test serta mengetahui pengaruhnya terhadap koordinasi motorik melalui uji Rotarod. Mencit jantan dibagi menjadi enam kelompok: kontrol normal, kontrol negatif (Na CMC 0,5%), kontrol positif (amitriptilin 25 mg/kgBB), serta ekstrak buah kundur dosis 100, 200, dan 400 mg/kgBB. Parameter yang diamati meliputi persentase entri ke lengan terbuka (OAE) dan persentase waktu di lengan terbuka (TSOA), serta latency to fall, durasi terlama, dan frekuensi jatuh pada uji Rotarod. Hasil uji EPM menunjukkan bahwa ekstrak etanol buah kundur meningkatkan entri dan waktu berada di lengan terbuka secara signifikan pada dosis 400 mg/kgBB yang mendekati kontrol positif (p>0,05) menunjukkan penurunan perilaku depresi. Pada uji Rotarod, dosis 400 mg/kg BB menyebabkan peningkatan latency to fall, durasi dan frekuensi jatuh tetapi tidak signifikan, mengindikasikan efek samping gangguan motorik lebih rendah dibanding kontrol positif (p<0.05).
Co-Authors Aswani, Aswani Fadhliyah Malik Fristiohady, Adryan Hariana, Hariana Jannah, Sitti Raodah Nurul Jatnika, Yayat Kasmawati, Henny Malina, Rachma Nuralifah Nuralifah, Nuralifah Parawansah Parawansah, Parawansah Suryani Suryani Trinovitasari, Nita wahyuni wahyuni