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All Journal Jurnal Pengabdian UNDIKMA Multidiciplinary Output Research for Actual and International Issue (Morfai Journal)
Rizki Andini Nawawi
Universitas Sriwijaya
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LITERATURE REVIEW OF EMBRYONIC DEVELOPMENT EPIGENETICS: CHROMATIN MODIFICATION AND CELL PROGRAMMING Kamila Alawiyah; Rizki Andini Nawawi; Meillisa Carlen Mainassy; Syarinta Adenina; Hamzah Alfarisi; Sternatami Liberitera
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 5 No. 6 (2025): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.18492220

Abstract

This study aims to comprehensively examine epigenetic mechanisms in embryonic development, focusing on the role of chromatin modification and cell programming as regulators of gene expression without changes in DNA sequence. The type of study used was qualitative , with a descriptive approach through literature review, which examined scientific literature from reputable international journals such as Nature, Trends in Genetics, and The FEBS Journal published between 2015 and 2025. Data were collected through systematic searches of scientific articles using thematic and inductive analysis techniques, including theme identification, data reduction, and concept categorization. The results of the study show that DNA methylation, acetylation, and histone methylation are key factors in regulating gene expression during the zygotic genome activation (ZGA) phase and the formation of cell lineages. This process demonstrates the complex interaction between epigenetic and transcriptional factors that determine the direction of cell differentiation. In addition, similarities in epigenetic regulation principles between mammals and plants were found, indicating the conservation of biological mechanisms across species. The implications of the study " " include the development of regenerative therapies, increased effectiveness of assisted reproductive technologies, and innovations in agricultural biotechnology. In conclusion, this study confirms that epigenetics is an important layer of regulation in developmental biology that enriches our understanding of the mechanisms of life formation from the earliest stages.
Diversifikasi Produk Recycling di Bank Sampah KGS Melalui Pembuatan Sabun Cair dari Minyak Jelantah Bijak Riyandi Ahadito; Neza Rahayu Palapa; Laela Mukaromah; Rizki Andini Nawawi
Jurnal Pengabdian UNDIKMA Vol. 7 No. 2 (2026): May
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v7i2.20084

Abstract

This community service program aims to enhance the knowledge and skills of administrators, customers, and surrounding community members of KGS Waste Bank in Palembang in utilizing used cooking oil waste through the application of simple technology to produce liquid soap with practical and economic value. The activity was carried out using a socialization approach combined with training on the production of liquid soap from used cooking oil through a cold saponification process. Evaluation instruments consisted of pre-test and post-test assessments, which were subsequently analyzed descriptively. The results of the program showed an improvement in participants’ understanding of the liquid soap production process from used cooking oil, as indicated by an increase in the average score of 16.94 points in the post-test. This activity successfully opened opportunities for product diversification among the program partners and is expected, through this transfer of knowledge, to enrich the portfolio of recycled products they produce.
Co-Authors Bijak Riyandi Ahadito Hamzah Alfarisi Kamila Alawiyah Laela Mukaromah Meillisa Carlen Mainassy Neza Rahayu Palapa Sternatami Liberitera Syarinta Adenina