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All Journal JOPS (Journal Of Pharmacy and Science) Rafflesia Journal of Natural and Applied Sciences (RJNAS)
Muthi, Muthia Nurhidayah
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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A Review Peran Pendekatan Network Pharmacology dalam Mengungkap Senyawa Aktif dan Mekanisme Kerja Pengobatan Tradisional Indonesia: Review: Peran Pendekatan Network Pharmacology dalam Mengungkap Senyawa Aktif dan Mekanisme Kerja Pengobatan Tradisional Indonesia Muthi, Muthia Nurhidayah
RAFFLESIA JOURNAL OF NATURAL AND APPLIED SCIENCES Vol. 5 No. 2 (2025): Oktober
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/rjna.v5i2.45481

Abstract

Pengobatan berbasis bahan alam di Indonesia telah digunakan secara turun-temurun, namun pengembangannya masih terhambat oleh keterbatasan pemahaman ilmiah terhadap komposisi dan mekanisme kerja senyawa aktif. Penelitian ini bertujuan untuk mengeksplorasi potensi pendekatan network pharmacology dalam mengungkap hubungan kompleks antara bahan alam, target biologis, dan jalur penyakit. Kajian dilakukan melalui penelusuran literatur dan analisis data bioinformatika yang diintegrasikan ke dalam basis data farmakologi jaringan. Hasil analisis menunjukkan bahwa network pharmacology mampu mengidentifikasi senyawa aktif utama serta target protein yang relevan, sekaligus memetakan interaksi biologis yang mendasari efek terapeutik bahan alam Indonesia. Pendekatan ini juga memperlihatkan potensi sinergi antar senyawa yang berkontribusi terhadap aktivitas farmakodinamik kompleks. Kesimpulannya, network pharmacology memberikan kerangka ilmiah yang kuat untuk memahami dan memvalidasi mekanisme kerja pengobatan berbasis bahan alam, serta menjadi landasan strategis dalam upaya modernisasi dan standarisasi obat tradisional Indonesia menuju pengobatan berbasis bukti.
Effect of Educational Videos on Osteoporosis Knowledge Among Menopausal Women in Semidang Alas Village, Pagar Alam City Reza Rahmawati; Delvia Novalisya; Delia Komalasari; Rizki Oktarini; Muthia Nurhidayah; Dian Handayani
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.7810

Abstract

Osteoporosis is a bone-loss disease caused by decreased estrogen levels, predominantly affecting menopausal women. Limited access to health information in rural areas remains a major barrier to early prevention efforts. This study aimed to determine the effect of educational videos on osteoporosis knowledge levels among menopausal women in Semidang Alas Village, Pagar Alam City. A pre-experimental design with a one group pre-test–post-test approach was employed, involving 83 respondents selected through total sampling. Prior to the intervention, 61 respondents (73.50%) demonstrated poor knowledge. Following the educational video intervention, a significant improvement was observed, with 76 respondents (91.60%) achieving good knowledge levels. The paired t-test results indicated a p-value of 0.000, confirming a statistically significant effect of the educational video on osteoporosis knowledge. It is concluded that audiovisual media is an effective health education strategy, particularly for rural communities with limited access to health information.
Co-Authors Delia Komalasari Delvia Novalisya Dian Handayani Reza Rahmawati Rizki Oktarini