Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Medicra (Journal of Medical Laboratory Science/Technology)
Anggraini, Lukita
Unknown Affiliation
Health Professions Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Cellular Immune Responses and Hepatitis B Surface Antigen (HBsAg) in Alcohol-Consuming Fishermen : Respon Imun Seluler dan HBsAg pada Nelayan Pengonsumsi Alkohol Purwaningsih, Nur Vita; Saputro, Tri Ade; Azizah, Fitrotin; Maulidiyanti, Ellies Tunjung Sari; Budiman, Waras; Anggraini, Lukita
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i2.1803

Abstract

Hepatitis B infection remains a global health problem with long-term complications such as cirrhosis and hepatocellular carcinoma. Alcohol consumption is known to impair immune function and exacerbate hepatitis B virus (HBV) infection. Fishermen represent a high-risk occupational group due to alcohol consumption habits and limited healthcare access. This study aimed to analyze the relationship between alcohol consumption levels and hepatitis B infection status through HBsAg testing and lymphocyte count among fishermen. This was a descriptive observational study with a cross-sectional approach involving 40 fishermen in Gresik Regency. Data were collected through alcohol consumption questionnaires and laboratory tests, including HBsAg examination using a Rapid Test and lymphocyte count using a hematology analyzer. Data were analyzed using Chi-square and ANOVA tests with a significance level of p < 0.05. A total of 30% of respondents were HBsAg reactive, with the highest proportion found in the heavy alcohol consumption group (50%). The mean lymphocyte count decreased with increasing alcohol intake: 2.580 ± 420 cells/µL in the light group, 2.120 ± 390 cells/µL in the moderate group, and 1.780 ± 360 cells/µL in the heavy group (p = 0.012). There was a significant relationship between alcohol consumption level, HBsAg status, and lymphocyte count among fishermen. High alcohol consumption may reduce cellular immunity and increase the risk of persistent hepatitis B infection. HBsAg testing and lymphocyte count can serve as early indicators for health screening in high-risk occupational groups such as fishermen. 
Co-Authors Budiman, Waras Ellies Tunjung Sari Maulidiyanti, Ellies Tunjung Sari Fitrotin Azizah, Fitrotin Nur Vita Purwaningsih, Nur Vita Saputro, Tri Ade