Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal JOURNAL OF Qualitative Health Research & Case Studies Reports JOURNAL OF Mental Health Concerns
Nasution, Artika Ananda Putri
Unknown Affiliation
Health Professions Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Overview of treatment success with short, long, and BPaL/M regimens in patients with drug resistant tuberculosis Nasution, Artika Ananda Putri; Soleha, Tri Umiana; Jausal, Anisa Nuraisa; Gozali, Achmad
JOURNAL OF Qualitative Health Research & Case Studies Reports Vol 6 No 1 (2026): January Edition 2026
Publisher : Published by: Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/quilt.v6i1.2220

Abstract

Background: Drug-resistant tuberculosis (DR-TB) remains a major challenge in global TB control efforts, particularly in middle-income countries such as Indonesia. Long-term regimens lasting 18–24 months have been associated with low treatment success rates due to their prolonged duration and high incidence of adverse drug reactions. More recent developments, namely the bedaquiline–pretomanid–linezolid regimen with or without moxifloxacin (BPaL/M), have demonstrated treatment success rates of up to 89–90% in international clinical trials. Purpose: To describe the treatment success of short-term, long-term, and BPaL/M regimens among patients with drug-resistant tuberculosis. Method: A retrospective descriptive study was conducted using medical record data of DR-TB patients who received long-term, short-term, or BPaL/M regimens during 2023–2024. Treatment outcome classification followed the WHO 2022 guidelines. The variables collected included patient characteristics, type of regimen, and treatment outcomes based on WHO standards: cured, treatment completed, treatment failed, lost to follow-up, and died. Results: Of the 148 DR-TB patients who met the inclusion criteria, 98 patients (66.2%) received long-term regimens, 17 patients (11.5%) received short-term regimens, and 33 patients (22.3%) were treated with the BPaL/M regimen. The treatment success rate (cured + treatment completed) for the short-term regimen was 76.5%, which was lower compared to the long-term regimen at 83.7%. The BPaL/M regimen demonstrated the highest treatment success rate at 87.9%. Conclusion: The treatment success rates for DR-TB patients at Dr. H. Abdul Moeloek Hospital indicate that the BPaL/M regimen provides the most favorable outcomes compared to long-term and short-term regimens. Keywords: BPaL/M Regimen; Drug-Resistant Tuberculosis; Long-Term Regimen; Short-Term Regimen; Treatment Success.    
Common antidepressant side effect profiles and their management: A literature review Putri, Nazwa Kania; Nasution, Artika Ananda Putri; Ratna, Maya Ganda; Putri, Giska Tri
JOURNAL OF Mental Health Concerns Vol. 4 No. 5 (2026): January Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Unit Penelitian dan Pengabdian Kep Akademi Keperawatan Baitul Hikmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/mhc.v4i5.2304

Abstract

Background: Antidepressant medications are widely used as a first-line treatment for depressive disorders and various other mental health conditions in both primary and hospital-based healthcare settings. Despite their proven efficacy in alleviating depressive symptoms, antidepressants are frequently associated with a range of adverse effects that may negatively impact patient adherence, treatment satisfaction, and long-term therapeutic outcomes. Understanding the safety profile of antidepressants is therefore essential for optimizing clinical management and improving treatment success. Purpose: To review and synthesize current scientific evidence regarding the commonly encountered adverse effect profiles of antidepressant medications and the strategies used for their management in clinical practice. Results: A literature review of studies published between 2020 and 2025 identified several frequently reported adverse effects associated with antidepressant use, including gastrointestinal disturbances, sleep disorders, sexual dysfunction, weight changes, and neurological symptoms such as headache and tremor. The adverse effect profiles varied across antidepressant classes, including selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants, and atypical antidepressants. Management strategies commonly reported in the literature included dose adjustment, switching antidepressant agents or drug classes, the use of adjunctive therapies to alleviate specific adverse effects, and continuous patient education and monitoring to enhance treatment tolerability and adherence. Conclusion: Antidepressant medications exhibit diverse adverse effect profiles that may compromise treatment effectiveness if not appropriately addressed. This literature review highlights the importance of recognizing commonly encountered adverse effects and implementing individualized, evidence-based management strategies to improve drug tolerability and patient adherence. An integrated and patient-centered approach is essential to optimize antidepressant therapy in clinical practice. Keywords: Antidepressants; Adverse Effects; Drug Safety Profile; Management; Literature Review.
Co-Authors Giska Tri Putri Gozali, Achmad Jausal, Anisa Nuraisa Putri, Nazwa Kania Ratna, Maya Ganda Tri Umiana Soleha