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All Journal Biology, Medicine, & Natural Product Chemistry
Abrijanto, Abrijanto
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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The Potency of Kuldon® Solution in The Healing Process of Aphthous Stomatitis Priandini, Dewi; Pakpahan, Alfred; Amtha, Rahmi; Sulistia, Aprilia Puspita; Abrijanto, Abrijanto
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1241-1245

Abstract

Objectives: This study aimed to assess the efficacy of Kuldon® solution in the healing process of aphthous stomatitis.  Methods: A double-blind randomized controlled trial was conducted involving 60 subjects (27 males, 33 females), randomly assigned to receive either Kuldon® solution (Drug A) or hyaluronic acid rinse (Drug B). Pain was evaluated using the Visual Analogue Scale (VAS), and lesion diameter was measured on days 2, 5, and 7. Data were analyzed using the Mann-Whitney test (p < 0.05). Results: Drug A showed a greater reduction in pain and lesion size compared to Drug B. By day 5, 100% of Drug A users reported no pain, with 90% showing lesion reduction.Conclusion: Kuldon® solution demonstrates significant therapeutic potential in managing aphthous stomatitis.
Co-Authors Alfred Pakpahan, Alfred Dewi Priandini, Dewi Rahmi Amtha Sulistia, Aprilia Puspita