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Siwi Hastuti
Universitas Duta Bangsa Surakarta
Education Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

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Aktivitas Tonikum Infusa Bunga Telang (Clitoria ternatea L.) terhadap Mencit dengan Metode Natatory Exhaustion dan Induksi Tidur Eli Yuliana. H; Siwi Hastuti; Rahmat Hidayat
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8214

Abstract

ABSTRACT Tonics are agents that can stimulate body activity, thereby delaying feelings of fatigue, lethargy, and exhaustion. This study aimed to determine the ability of butterfly pea flower infusion to increase swimming time and its potential effect on the sleep duration of mice, as well as to evaluate the relationship between dose variation and tonic effects. Butterfly pea flower contains secondary metabolites such as alkaloids and flavonoids, which are known to produce tonic effects. This experimental study used 25 mice as test animals, divided into five groups. The test groups consisted of a negative control (distilled water), a positive control (caffeine 100 mg), and butterfly pea flower infusion at doses of 10%, 20%, and 40%. The results showed that butterfly pea flower infusion exhibited tonic effects in both the natatory exhaustion and sleep induction methods. The 10% dose produced tonic effects of 38.99% ± 10.34% in the natatory exhaustion method and 17.72% ± 6.13% in the sleep induction method. The 20% dose resulted in tonic effects of 52.82% ± 7.39% and 39.38% ± 6.22%, respectively. The 40% dose produced the greatest tonic effect, with values of 79.53% ± 3.82% in the natatory exhaustion method and 59.55% ± 1.72% in the sleep induction method. Keywords: Butterfly Pea Flower, Infusion, Natatory Exhaustion, Sleep Induction, Tonic
Formulasi dan Uji Aktivitas Antioksidan Face Toner Ekstrak Etanol Daun Yakon (Smallanthus sonchifolius) Menggunakan Metode DPPH Fika Riyanti; Bagas Ardiyantoro; Siwi Hastuti
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Excessive exposure to sunlight can cause the formation of free radicals that can damage skin tissue, thus requiring natural antioxidants. The use of natural ingredients as a source of antioxidants in the form of topical preparations is a potential alternative. This study aims to formulate ethanol extract of yakon leaves (Smallanthus sonchifolius) into a face toner formulation and evaluate its physical quality, antioxidant activity, and to determine the optimal concentration of the face toner formulation that can inhibit free radicals. Extraction was carried out using the maceration method with 70% ethanol, then formulated into face toner with different concentrations, namely 1%, 2%, and 3%. After that, physical quality evaluation was carried out in the form of organoleptic tests, pH tests, homogeneity tests, and viscosity tests. Antioxidant activity was tested using the DPPH method and measured using UV-Vis spectroscopy at a wavelength of 520 nm. The results showed that all formulas met the physical quality test standards and had antioxidant activity at concentrations of 1%, 2%, and 3% with IC50 values of 95.91, 93.58, and 91.70, respectively, all of which were classified as strong. while the negative control formula without extract had a value of 167 (weak category), and the positive control quercetin had a value of 9.95 (very strong category).
Co-Authors Bagas Ardiyantoro Eli Yuliana. H Fika Riyanti Rahmat Hidayat