Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Journal of Medical Studies
Mahrunnisa Rienti Sepestian
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Other

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The The Correlation of Neutrophil-to-Lymphocyte Ratio with LupusQoL in Systemic Lupus Erythematosus Patients Mahrunnisa Rienti Sepestian; Lipinwati; Dewi, Hasna; Hanina; Nyimas Natasha Ayu Shafira
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies (Ongoing Issue)
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40840

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations depending on disease activity. Clinical manifestations, disease activity, and side effects of treatment can affect quality of life. The LupusQoL questionnaire assesses the disease's impact on eight quality of life domains. The Neutrophil-to-Lymphocyte Ratio (NLR) is an inflammatory biomarker that correlates with SLE disease activity. Objective: This research aims to determine the correlation between NLR and various domains of the LupusQoL questionnaire in SLE patients. Methods: This observational analytic study used purposive sampling, involving 32 SLE patients treated at Raden Mattaher Hospital, Jambi, in 2024. NLR was obtained from blood counts performed within the last 4 weeks, and HRQOL was measured using the LupusQoL questionnaire. Data were analyzed using Pearson correlation. Result: The mean NLR was 6.50 (1.3–29.43). LupusQoL showed the lowest score in fatigue (58.85). Pearson analysis revealed a moderate inverse correlation between NLR and the planning domain of LupusQoL (p= 0,022). NLR shows no statistically significant correlation with physical health, pain, intimacy, burden to others, emotional health, body image, or fatigue in SLE patients, as p-values >0.05. Conclusion: Higher NLR is correlated with lower planning domain HRQoL in SLE patients and vice versa.
Co-Authors dewi, hasna Hanina Lipinwati ., Lipinwati Nyimas Natasha Ayu Shafira