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All Journal Journal of Science and Clinical Pharmacy Research
Aivi Yola Dwiputri
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Medicine & Pharmacology

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HUBUNGAN TINGKAT PENGETAHUAN DAN SIKAP MASYARAKAT DALAM PENGGUNAAN ANTIBIOTIK TANPA RESEP DI DUA APOTEK DI KECAMATAN PANGKALAN KOTO BARU Legianda Efendi; Ariesta Kirana Efmisa; Rido Farnandi; Aivi Yola Dwiputri
Journal of Science and Clinical Pharmacy Research Vol. 2 No. 1 (2026): February 2026
Publisher : LPPM Universitas Mohammad Natsir Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1144/jscpr.v2i1.424

Abstract

The use of antibiotics without prescription remains a community health issue that increases the risk of bacterial resistance and reduces treatment effectiveness. This study aimed to determine the relationship between the level of knowledge and attitudes of the community regarding the use of antibiotics without prescription in two pharmacies located in Pangkalan Koto Baru District. The research employed an analytic design with a cross-sectional approach. The study involved 100 respondents selected using purposive sampling who met the inclusion criteria. Data were collected using a structured questionnaire covering sociodemographic characteristics, knowledge, and attitudes related to antibiotic use. Data were analyzed using univariate, bivariate chi-square tests, and multivariate analysis to determine the strength of associations between variables. The results showed that most respondents had a moderate level of knowledge and a positive attitude toward the use of antibiotics without prescription. Chi-square analysis indicated a significant relationship between knowledge level and community attitudes (p < 0.05). The study concluded that better knowledge is associated with more positive attitudes toward rational antibiotic use. Continuous education through pharmacies and healthcare providers is necessary to improve community awareness of appropriate antibiotic use and prevent the emergence of resistance.
Evaluasi Penggunaan Antibiotik Pada Pasien Bronkopneumonia Anak Di Ruang Perawatan Melati Rsud Mukomuko Tahun 2024 Febria Mutiara, Elsa; Ariesta Kirana Efmisa; Devahimer Harsep Rosi; Aivi Yola Dwiputri
Journal of Science and Clinical Pharmacy Research Vol. 2 No. 1 (2026): February 2026
Publisher : LPPM Universitas Mohammad Natsir Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1144/jscpr.v2i1.433

Abstract

Bronchopneumonia is an inflammatory lung condition affecting one or more lobes, characterized by infiltrative patches caused by bacteria, viruses, fungi, and foreign substances. The purpose of this study was to obtain an overview and analysis of the appropriateness of antibiotic use. This was a descriptive observational study with a retrospective approach using secondary medical record data. The results for the description of antibiotic use were Seftriakson (53.4%), Sefotaksim (27.6%), and meropenem (19.0%). The results of the quality assessment using the Gyssens Method revealed that 1.7% of antibiotic prescriptions were in category III B, 19% in category IV A, and 79.3% in category 0. These data indicate that there is still irrational use of antibiotics. Assessed using the ATC/DDD methodology, resulting in a total of 25.57 DDD per 100 days. The calculation findings show the highest Defined Daily Dose (DDD) value for the antibiotic Seftriakson at 18.06 DDD per 100 days of hospitalization, while the lowest value was seen for Meropenem at 2.09 DDD per 100 days and Sefotaksim at 5.42 DDD per 100 days of hospitalization. Clinical parameters showed a P value > 0.05, with p = 0.88, indicating no statistically significant difference between antibiotic administration and leukocyte levels in pediatric bronchopneumonia patients in the Melati ward at Mukomuko Hospital in 2024.
Co-Authors Ariesta Kirana Efmisa Devahimer Harsep Rosi Febria Mutiara, Elsa Legianda Efendi Rido Farnandi