Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal PCJN Pharmaceutical and Clinical Journal of Nusantara Journal of Biomedical Sciences and Health
Manery, Dodikrisno Ekaputra
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
The Potential of Ethanol Extract from Langsat Leaves (Lansium Domesticum Var. Pubescent) In Controlling Aedes Aegypti Mosquitoes: A Study on The Effectiveness of Natural Substances as Mosquito Repellents Ukratalo, Abdul M; Ichsan, Muhammad Nurhidayat; Kaihena, Martha; Manery, Dodikrisno Ekaputra; Pangemanan, Victory Osvaldo; Moniharapon, Debby Dijola
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.1

Abstract

In recent decades, attention to the utilisation of natural materials as alternatives in vector control has increased. One potential source that needs to be explored is langsat leaves, which are known to have active compounds. Ethanol extracts of langsat leaves may contain compounds that can provide control effects against Aedes aegypti mosquito larvae. This study aims to assess the effectiveness of the ethanol extract of langsat leaves in controlling Aedes aegypti mosquitoes, the vector of Dengue Fever disease. The extraction method was carried out using the maceration technique with ethanol as the solvent. Bioactivity test was conducted through larvicidal bioassay against Aedes aegypti larvae. The results showed that the ethanol extract of langsat leaves has a larvicidal effect against Aedes aegypti mosquito larvae. The toxicity levels, both LC50 and LC90, indicate that the ethanol extract of langsat leaves has potential as a mosquito larva control agent.
Potential Bark Cinnamomum burmanii in Regenerating Damaged Liver Cells of Mice (Mus musculus) Diabetes Mellitus Model Ukratalo, Abdul M; Kaihena, Martha; Sirait, Dion P O; Pattimura, Nadira; Manery, Dodikrisno Ekaputra
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 02 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (752.864 KB) | DOI: 10.58549/pcjn.v2i01.58

Abstract

Diabetes mellitus is a chronic disease that can quickly increase the prevalence of complications in sufferers, such as liver damage. This study aims to examine the effect of methanol extract cinnamon bark (Cinnamomum burmanii Bl) in regenerating liver cell damage mice (Mus musculus) Diabetes Mellitus through the histological picture. 20 mice were divided into 5 groups which consisted of a negative control group, Positive control and a group of mice that were given methanol extract bark Cinnamomum burmannii dose of 125 mg/head/day, 250 mg/head/Day and 500 mg/head/day. In the positive control group and the group of mice that will be given extract streptozotocin injected dose of 0.2 ml and observed blood sugar levels if sugar levels have increased then given methanol extract bark Cinnamomum burmannii with a dose that has been determined and blood sugar levels were measured. On the last day, surgery is performed to remove the liver, after which histological preparations are made. The results showed that the administration of bark extract Cinnamomum burmanii can regenerate damaged liver cells of mice due to diabetes mellitus. This is due to the content of secondary metabolite compounds contained in the bark of Cinnamomum burmannii.
Co-Authors Ichsan, Muhammad Nurhidayat Martha Kaihena Moniharapon, Debby Dijola Nadira Pattimura Pangemanan, Victory Osvaldo Sirait, Dion P O Ukratalo, Abdul M