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All Journal International Journal of Public Health Science (IJPHS) Indonesia Berdaya
Isrovanigoro, Isrovanigoro
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Arts Humanities Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Peningkatan Pengetahuan Siswa SMK Kesehatan Bantul tentang DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) Kosmetik melalui Edukasi Kesehatan Utami, Fella Arifatul Wahyu; Wahyuningsih, Iis; Isrovanigoro, Isrovanigoro; Arib, Faisal Nur
Indonesia Berdaya Vol 7, No 2 (2026)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20261457

Abstract

Remaja merupakan kelompok konsumen kosmetik yang besar namun rentan terhadap paparan produk ilegal dan informasi yang tidak tervalidasi di media sosial. Kurangnya literasi mengenai keamanan produk dapat berdampak buruk bagi kesehatan kulit. Kegiatan Program Pemberdayaan Umat (PRODAMAT) ini bertujuan untuk meningkatkan pengetahuan dan literasi keamanan produk kecantikan pada siswa SMK Kesehatan Bantul melalui edukasi DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) Kosmetik. Metode yang digunakan adalah edukasi partisipatif dengan desain evaluasi pre-test dan post-test melalui tahapan persiapan, pre-test, intervensi edukasi, dan post-test. Intervensi mencakup pemaparan materi dan diskusi interaktif tentang DAGUSIBU Kosmetik. Hasil evaluasi terhadap 18 peserta menunjukkan peningkatan skor rata-rata pengetahuan secara signifikan dari 65,00±12,95 menjadi 95,56±7,05. Analisis uji Wilcoxon Signed Ranks menghasilkan nilai p = 0,000 (p 0,05), didukung dengan nilai rata-rata N-gain sebesar 0,909 yang termasuk dalam kategori efektivitas tinggi. Simpulan dari kegiatan ini adalah edukasi DAGUSIBU Kosmetik efektif dalam meningkatkan domain kognitif siswa sebagai fondasi perilaku penggunaan kosmetik yang aman dan rasional. Program ini diharapkan dapat membangun kesadaran kritis remaja dalam menghadapi tren di era digital.
Tacrolimus outcomes in adult kidney transplants: a decade review Lolita, Lolita; Isrovanigoro, Isrovanigoro; Puspitasari, Metalia; Wang, Zijie
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.26879

Abstract

Tacrolimus remains a principal immunosuppressive agent in kidney transplantation, yet its reported efficacy and safety vary due to differences in study design, treatment regimens, and patient characteristics. Objectives: To summarize recent evidence on the clinical performance of tacrolimus in adult kidney transplant recipients and identify factors contributing to variability in outcomes. A narrative review was conducted using PubMed as the primary database because of its comprehensive indexing of clinical and pharmacological studies relevant to transplant immunosuppression. Additional databases were screened to ensure completeness. Studies published between 2015 and 2025 were searched using predefined keywords. Of 91 open-access articles identified, 19 met the inclusion criteria and were analyzed. Results: Reported clinical outcomes demonstrated wide variability across studies. Acute rejection ranged from 0-18.8%, while biopsy-proven acute rejection varied substantially (0-85%). Graft loss occurred in 0-15% of recipients and mortality in 0-8%. Major adverse events were also heterogeneous, including cytomegalovirus (CMV) infection (0-16.9%), new-onset diabetes after transplantation (NODAT) (0-22.8%), and tremor (3-28.6%). Variability in findings was largely influenced by differences in study methodology, concomitant immunosuppressive protocols, monitoring practices, population characteristics, and limited ethnic diversity, as most participants were Caucasian. Tacrolimus maintains a strong efficacy-safety profile in adult kidney transplantation. Future studies with more diverse populations, standardized therapeutic drug monitoring, and longer follow-up durations are required to enhance generalizability and support individualized immunosuppressive management.
Co-Authors Arib, Faisal Nur Iis Wahyuningsih Lolita Lolita Metalia Puspitasari Utami, Fella Arifatul Wahyu Wang, Zijie