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All Journal Jurnal Abdi Kesehatan dan Kedokteran Variable Research Journal
Sukowati, Eko Gunawan
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Pentatalaksanaan Bedah Myxofibrosarcoma Punggung Kronis: Sebuah Laporan Kasus: Surgical Management of Chronic Myxofibrosarcoma of the Back: A Case Report Sukowati, Eko Gunawan; Nugroho, Dodhi Kuncoro Setiyo; Lestari, Rinna Dwi
Jurnal Abdi Keperawatan dan Kedokteran Vol 5 No 1 (2026): Jurnal Abdi Kesehatan dan Kedokteran
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/jakk.v5i1.174

Abstract

Soft tissue sarcoma is a rare malignant tumor that can arise in various parts of the body, including the back. One of its subtypes, myxofibrosarcoma, is known for its relatively slow growth but high risk of local recurrence, making early diagnosis and appropriate management crucial. This case report aims to describe the diagnostic process, surgical management, and functional as well as aesthetic outcomes in a patient with back myxofibrosarcoma. This study used a descriptive case report design involving a 63-year-old male patient who presented with a back mass that had been developing for approximately 20 years. The observed variables included the clinical characteristics of the mass, anatomical pathology findings, type of surgical intervention, and postoperative condition. The assessment tools consisted of clinical physical examination, histopathological evaluation of tumor tissue, and observation of functional outcomes and the patient’s ability to perform daily activities after surgery. The examination results revealed a large soft tissue mass with dilated blood vessels on the back. Anatomical pathology confirmed a malignant mesenchymal tumor suggestive of myxofibrosarcoma. The patient underwent wide excision followed by flap reconstruction. Postoperatively, the patient’s general condition was stable without significant complications, the surgical wound improved, and the patient was able to return to normal activities as a construction worker after routine follow-up and care. This case demonstrates that soft tissue sarcoma of the back, although progressive in appearance and often concerning, can yield good clinical outcomes when managed with adequate surgical intervention according to indications. Patient education regarding the potential success of therapy plays an important role in improving treatment adherence, trust in medical procedures, and optimization of postoperative functional and aesthetic results.
POTENSI AKTIVITAS ANTIBAKTERI BAKTERI ASAM LAKTAT TC3 YANG DIISOLASI DARI TAUCO FERMENTASI TERHADAP CUTIBACTERIUM ACNES DAN STAPHYLOCOCCUS AUREUS Ramadhan, Bey Jalasukma; Pribadhi, Adhitya Naufal; Sukowati, Eko Gunawan; Suwanto, Yustiana Arie
VARIABLE RESEARCH JOURNAL Vol. 3 No. 01 (2026): JANUARI 2026
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Infeksi kulit dan peradangan jerawat umumnya dikaitkan dengan Staphylococcus aureus dan Cutibacterium acnes, sementara peningkatan penggunaan antibiotik berkontribusi pada resistensi antimikroba dan gangguan mikrobioma. Studi ini menghasilkan aktivitas antibakteri isolat bakteri asam laktat (LAB) TC3 yang berasal dari tauco fermentasi terhadap C. acnes dan S. aureus  menggunakan metode difusi cakram agar. Kultur LAB diinkubasi selama 24 dan 48 jam, dan zona inhibisi diukur dalam milimeter. Klindamisin dan air suling steril digunakan sebagai kontrol positif dan negatif. LAB TC3 yang diinkubasi selama 24 jam menghasilkan zona inhibisi rata-rata 10 ,25 mm terhadap kedua patogen, menunjukkan aktivitas antibakteri sedang. Inkubasi 48 jam menunjukkan inhibisi yang berkurang (9 ,00 mm untuk C. acnes dan 8,50 mm untuk S. aureus ). Klindamisin menunjukkan aktivitas yang lebih tinggi (16 ,13 mm), sedangkan kontrol negatif tidak menunjukkan inhibisi. Hasil ini menunjukkan bahwa LAB TC3 menunjukkan efek antibakteri terukur yang dipengaruhi oleh durasi inkubasi. Meskipun kurang ampuh dibandingkan antibiotik konvensional, isolat ini menunjukkan potensi sebagai kandidat antimikroba tambahan yang kompatibel dengan mikrobioma untuk aplikasi dermatologis
Co-Authors Nugroho, Dodhi Kuncoro Setiyo Pribadhi, Adhitya Naufal Ramadhan, Bey Jalasukma Rinna Dwi Lestari Suwanto, Yustiana Arie