Pri Hardini
Institut Ilmu Kesehatan Bhakti Wiyata Kediri

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Profil Penggunaan Obat dan Suplementasi pada Pasien Thalasemia di Rumah Sakit Daerah: Implikasi terhadap Kebijakan Pelayanan Kesehatan Nasional dewy basuki; Yogi Bhakti Marhenta; Pri Hardini
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.936

Abstract

Thalassemia is a chronic genetic disorder requiring lifelong management, including regular blood transfusions, iron chelation therapy, and supportive supplementation. Regional hospitals play a strategic role in providing thalassemia care; however, data on drug and supplement utilization at the regional level remain limited. This study aimed to describe the profile of drug and supplement use among thalassemia patients in regional hospitals and to analyze its implications for national health service policies. This study employed a descriptive observational design with a retrospective approach. Data were collected from medical records of thalassemia patients treated at RSUD Ngudi Waluyo Wlingi, Blitar Regency, and RSUD Jombang, East Java. Variables observed included patient characteristics, transfusion therapy, iron chelation drugs, and supportive supplementation. Data were analyzed descriptively. The results showed that most patients with thalassemia major received regular blood transfusions and iron chelation therapy. Deferiprone was the most commonly used iron chelator, while folic acid was the main supportive supplement. Variations in additional supplementation, such as vitamin E and vitamin D, were observed between hospitals. Overall, treatment patterns were generally consistent with national guidelines, although variations in clinical practice were identified. The profile of drug and supplement use among thalassemia patients in regional hospitals generally aligns with national guidelines; however, variations in practice remain. These findings provide important evidence to support evaluation and strengthening of national health service policies to improve the quality and equity of thalassemia care in Indonesia.
Acceptability and Organoleptic Properties of a Herbal Drink Formula Made from Averrhoa bilimbi Leaves with Turmeric Addition as a Healthy Drink Niken Dwi Prasiska; Dhini Prasetiya Ningrum; Lusifa Anggraini; Luthfi Assyaukani; Zalfa Aqilla Putri Zain; Pri Hardini; Arya Ulilalbab
Ficco Public Health Journal Vol. 3 No. 01 (2026): January-April 2026
Publisher : Ficco Scientific Corner

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.21538662

Abstract

Background Previous studies have shown that Averrhoa bilimbi leaves can help lower blood pressure. These leaves also act as diuretics and antioxidants. Combining Averrhoa bilimbi leaves and turmeric is expected to create a herbal beverage healthy drink. This study aimed to analyze the organoleptic and acceptability tests of a functional herbal drink made with Averrhoa bilimbi leaves and turmeric that could benefit health. Methods: The research employed an experimental quantitative design with a factorial design (one factor). A total of 30 respondents participated by completing a questionnaire. Sampling was done using a convenience sampling method. Results: There were significant differences in color, aroma, and taste (p < 0.05), but not in texture (p = 0.104). The formulation without Averrhoa bilimbi leaves (P0) was the most preferred overall compared to P1 and P2. Conclusions: The addition of turmeric significantly affected the color, aroma, and taste, but not the texture. The formulation without turmeric (P0) was the most preferred by the panelists.
EVALUATION OF ANTIDIABETIC DRUG UTILIZATION USING THE ATC/DDD AND DU 90% METHODS AT PUSKESMAS MRICAN Umul Farida; Faizatul Fitria; Pri Hardini; Mohammad Charist Ilham Fajrin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 2 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i2.3042

Abstract

Diabetes mellitus is a chronic metabolic disorder that requires long-term pharmacological therapy and continuous monitoring of drug utilization. Evaluation of antidiabetic drug utilization is essential to identify prescribing patterns and support rational drug use in healthcare facilities. This study aimed to evaluate the utilization of antidiabetic drugs among outpatients with type 2 diabetes mellitus at Puskesmas Mrican using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) and Drug Utilization 90% (DU 90%) methods. This study employed a non-experimental observational design with a retrospective descriptive approach using a total sampling technique. The study sample consisted of 330 outpatient prescriptions of patients with type 2 diabetes mellitus during the June–September 2022 period that met the inclusion criteria. Data were analyzed using the ATC/DDD method to calculate DDD/1000 outpatient visits and the DU 90% method to identify the most dominantly utilized drugs. The results showed that the average daily utilization of metformin, glibenclamide, and glimepiride remained within the Defined Daily Dose (DDD) range recommended by the World Health Organization. Glimepiride demonstrated the highest DDD/1000 outpatient visits values, namely 33.33 in June, 32.29 in July, 32.89 in August, and 30.30 in September. DU 90% analysis indicated that glimepiride, metformin, and glibenclamide were included in the DU 90% segment, with glimepiride being the most predominantly utilized antidiabetic drug. This study provides an overview of antidiabetic drug utilization patterns in primary healthcare facilities and may serve as a basis for drug use evaluation to support the quality of pharmaceutical care services.