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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology
Musa Yahaya Abubakar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Public Health Social Sciences

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Organocatalysis: A Revolutionary Approach in Organic Synthesis Kabiru Bashir Ahmad; Emmanuel Kinsley Chinedu; Reuben Pambani; Ansar Bilyaminu Adam; Musa Yahaya Abubakar; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3518

Abstract

Organocatalysis has emerged as a powerful tool in organic synthesis, enabling the efficient and selective formation of complex molecules. This review highlights the recent advances in organocatalysis, including the development of new catalysts, reactions, and applications. The advantages and limitations of organocatalysis are discussed, and its potential for scalability and sustainability is evaluated. The review also explores the mechanistic insights and future directions in this field, demonstrating the versatility and impact of organocatalysis in modern organic synthesis. This paradigm shift not only addresses the pressing environmental challenges but also paves the way for more innovative and economically viable synthetic strategies. As a result, organic synthesis is poised to play a crucial role in advancing pharmaceuticals, materials science, and agrochemicals, driving forward a more sustainable and resilient chemical industry.
The Impact of Water Quality on Human Nutrition: A Review of the Relationship between Water Intake and Nutrient Absorption Musa Yahaya Abubakar; Mohammed Haladu; Pambani Reuben; Twan Sale Mathew; Ansar Bilyaminu Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3544

Abstract

Water quality is intrinsically linked to human health, and ensuring access to clean and safe water is a fundamental public health goal, Water is essential to human health as it assists with nutrient delivery and digestion. The chemical, physical, and microbiological qualities of water have a substantial impact on the gastrointestinal tract's ability to absorb nutrients. Heavy metals, insecticides, and microbial infections are examples of contaminants that can hinder digestive processes, resulting in nutrient shortages and absorption. Pure, high-grade water can improve the absorption of nutrients and the effectiveness of digestion. This review examines the connection between nutrient absorption and water quality, with a particular emphasis on the effects of water pollution on human health. According to the review, nutrient absorption is greatly impacted by water quality, particularly in groups that are more sensitive. It emphasizes how crucial it is to monitor and control water quality better in order to provide the best possible nutrition and health results. This review synthesizes current research to elucidate the mechanisms through which water quality impacts nutrient absorption and overall nutritional status. It also highlights the public health implications, particularly in areas with inadequate access to clean water, and suggests interventions to improve water quality and support optimal health outcomes. water quality has a significant impact on human nutrition by influencing nutrient absorption, overall health, and hydration. Contaminants in water can interfere with nutrient absorption and cause a range of health issues, ultimately affecting the availability of essential nutrients in the body. Therefore, addressing water quality issues is crucial for promoting optimal nutrition and improving human health. The findings underscore the importance of ensuring access to clean drinking water as a fundamental component of nutritional health and public well-being.
Natural Products as Leads for Neglected Trophical Diseases (NTDs) Treatment; A Chemical and Biological - Review Twan Sale Mathew; Emmanuel Kinsley Chinedu; Muhammed Haladu; Musa Yahaya Abubakar; Ansar Bilayamin Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3735

Abstract

Natural compounds are mostly found in medicinal plants that are used to treat various ailments. They are distinguished by their structural complexity and diversity, which span a wide chemical universe and present both benefits and shortcomings to the process of discovering novel drugs. Neglected tropical diseases (NTDs) are common tropical diseases that impact over one billion people globally. Numerous pathogens, such as bacteria, fungi, viruses, parasites, and poisons, are responsible for them. Natural products have always been important in the search for new drugs to treat differents diseases including NTDs. The purpose of this chapter is to provide an update on the evaluation of both the chemical and biological properties of natural compounds that have been extracted and identified from plant sources, and may be utilized as viable candidates for the development of new drugs treat NTDs with lower incidence such as: Buruli ulcer, dracunculiasis, echinococcosis, food-borne trematodiases, leprosy, lymphatic filariasis, parasitics, schistosomiasis, soil-transmitted helminthiases, taeniasis/cysticercosis, trachoma and yaws. This chapter also intends to make a critical review on the chemical analysis of natural products’ structure and classification, biological evaluation of natural products’ antiparasitic, anti-inflammatory and immunomodulatory activities. In conclusion, Natural products continue to be a key source of fresh ideas for treating NTDs. Their distinct methods of action and variety of chemicals offer potential for the development of new treatments.
Physicochemical Parameters of Borehole Water, Tap Water and Well Water from Dawakin Kudu Local Government Area of Kano State, Nigeria Abdullahi Mustaph Idris; Musa Yahaya Abubakar; Haladu Mohammad; Shittu Abubakar Muhammad; Twan Sale Mathew; Ansar Bilyamin Adam
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3737

Abstract

Quality water is very important for maintenance of healthy environment, to determine the safety of the water consumed in the environment, pH, Turbidity, electrical conductivity, Alkalinity and hardness of water samples borehole, tap and well were analyzed. The result of the study showed that the pH of the water samples were found to be 6.3borehole, 6.7 tap and 6.8 well water, Turbidity were found to be 0 borehole, 1 tap and 0(NTU) well water, while conductivity were found to be 401 borehole, 635 tap and 556(µS/cm), well water and Hardness were found to be 172borehole, 68 tap and 88 mg/ml well water . The physicochemical analysis carried out the pH of the water were found to be from 6.3 to 6.8 only two of the samples are below the ranges laid down by W.H.O which are sample A and D and in conductivity also two of the samples are above the limit which are sample B and C and for the total hardness all are below the permissible limit by the standard (W.H.O).
Exploring the Chemical Properties and Mechanisms of Herbal Remedies in Moringa, and Ginger in Managing Chronic Diseases: Review Musa Yahaya Abubakar; Twan Sale Mathew; Ansar Bilyaminu Adam; Kabiru Bashir Ahmad; Hylalibiya Ataitiya; Aminu Ado Kaugama
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 1 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i1.3472

Abstract

Herbal remedies have been used for centuries to treat various ailments. Natural products, derived from plants, animals, and microorganisms, have been used for centuries as a source of medicinal compounds in traditional and modern herbal remedies. Understanding the chemical properties and mechanisms of action of these remedies is crucial for their effective and safe application in managing chronic diseases. This review explores the effectiveness of herbal remedies in managing chronic diseases such as diabetes, cardiovascular diseases, and autoimmune disorders. It emphasizes the need for a balanced approach combining herbal and conventional medicine, reducing healthcare costs and improving patient outcomes. The review includes 10 studies investigating the efficacy of herbal remedies in managing chronic diseases in Moringa and Ginger. Moringa, a valuable plant in traditional and modern medicine, has diverse therapeutic effects, making it beneficial for managing chronic diseases. Ginger, a powerful herbal remedy with bioactive compounds like gingerols, shogaols, zingerone, and paradols, is also considered a powerful natural treatment due to its antioxidant, anti-inflammatory, antimicrobial, antiemetic, and anticancer activities. Understanding the chemical properties and mechanisms of action of these remedies can help develop effective treatments for chronic diseases and enhance their integration into modern medicine.
The Devastating Impact of Heavy Metal Contamination on Plant Growth and Development: Unveiling Phytotoxicity and Exploring Remediation Strategies Hylalibiya Ataitiya; Kabiru Bashir Ahmad; Aminu Ado Kaugama; Shamsu Abdullahi Idris; Ansar Bilyaminu Adam; Musa Yahaya Abubakar; Twan Sale Mathew
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3495

Abstract

Heavy metal contamination poses a significant threat to plant growth and development, leading to reduced crop yields, impaired ecosystem functioning, and potential human health risks. This review provides a comprehensive overview of the phytotoxic effects of heavy metals on plant species, highlighting the mechanisms of uptake, transport, and accumulation. We explore the devastating impacts on plant morphology, physiology, and biochemistry, including altered root architecture, reduced photosynthesis, and impaired reproductive development. This review highlights the urgent need for effective remediation approaches to mitigate the phytotoxic effects of heavy metals and ensure sustainable ecosystem functioning. We identify knowledge gaps and future research directions, emphasizing the importance of interdisciplinary collaboration to address this critical environmental issue.
Challenges and Opportunities in Repurposing Natural Products for the Treatment of Neglected Trophical Diseases: A Review of Scaffold Optimization Strategies Musa Yahaya Abubakar; Twan Sale Mathew; Ruslan Shamsuddeen; Saeed Abdullahi; Ansar Bilyamin; Emmanuel Kinsley Chinedu
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3725

Abstract

Neglected Tropical Diseases (NTDs) are serious health issues that affect the entire world, especially in low-income tropical and subtropical areas, yet they do not get enough facilities. Natural items have great potential for treating NTD because of their varied chemical scaffolds. Nevertheless, there are a number of difficulties in optimizing these scaffolds for drug development. Attempts at synthesis and modification are complicated by the structural complexity of natural compounds. Economic and regulatory hurdles also obstruct advancement. Despite these difficulties, there are plenty of chances. Natural products are a significant source of structural variety that makes them ideal for drug discovery. developments in biotechnology and synthetic biology. Sustainable production is improved via biotechnology. Targeted optimization is made easier by advances in computer power and molecular understanding. Research collaborations can expedite the process of discovery and development. Finding efficient scaffolds can be done quickly by looking for NTD activity in already-existing natural product libraries. By tackling these issues scientifically and cooperatively, we can develop novel, practical, and affordable treatments for non-traumatic disabilities (NTDs), which will eventually improve the health of impacted communities.
Effect and Remediation of Environmental Pollution on the Concept of Chemistry - Review Musa Yahaya Abubakar; Mohammed Haladu; Ogunwole Adeshewa Titilayo; Ansar Bilyamin Adam
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3726

Abstract

The science of chemistry has been greatly impacted by environmental degradation, which has led to important breakthroughs and changed educational perspectives. This review highlights the role of chemists in tackling global environmental concerns by examining the diverse effects of environmental contamination on the study of chemistry. Green chemistry principles, which attempt to design safer chemicals and processes that limit waste and lessen detrimental environmental impacts, have been motivated by pollution. Environmental chemistry, which focuses on the behavior, consequences, and mitigation of pollutants, has emerged as a crucial sub-discipline as a result of the pressing need to address pollution. In addition, pollution has made it necessary to integrate interdisciplinary techniques, bringing together the fields of chemistry, biology, environmental science, and engineering to provide novel ways to pollution treatment and control. Educational curricula have evolved to incorporate these trends, emphasizing sustainable practices and the environmental implications of chemical processes. This review highlights how the growing awareness of environmental pollution continues to drive innovation and shape the future of chemical education and research, underscoring the importance of chemists in developing sustainable solutions to protect our planet.
Assessment of Lead and Cadmium of Hand Dug Well Around Gold Mining Areas of Rimi Sumaila Local Government Area, Kano State, Nigeria Musa Yahaya Abubakar; Danladi Mudwa Dwanga; Ansar Bilyamin Adam; Shittu Abubakar Muhammad; Usman Sabiu Usman
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3727

Abstract

Heavy metals are essential element that are very important to the soil, their accumulation beyond the permissible limit causes a health risk as it may affect the soil and plants. Mining activities can generate large quantities of heavy metals laden waste which are released in an uncontrolled manner, causing widespread contamination of the ecosystem. Heavy metals are important for normal life psychological process and also provide enormous social and economic benefit to nations, the lung time adverse effect on the environment and public health cannot be overlooked This study investigates the presence of lead and cadmium metals hand dug well around gold mining areas of Rimi Local Government, Kano State. The metals determined were lead and chromium, and the permissible limit for lead in water is 0.1mg/L according to (WHO, 2008). By consideration with the WHO (2008) acceptable limit all the ten-hand dug well water in Rimi are beyond the permissible limit. The highest lead concentrations in water lead to several disease to body organs such as brain, kidney gastrointestinal tracts and central nervous system.
Determination of Trace Metals in Borehole, Tap, and Well Water from Dawakin Kudu Local Government Area of Kano State, Nigeria Abdullahi Mustapha Idris; Shittu Abubakar Muhammad; Twan Sale Mathew; Musa Yahaya Abubakar; Ibrahim Sani; Ansar Bilyaminu Adam
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3567

Abstract

This study investigates the concentration of trace metals in borehole, tap, and well water samples from Dawakin Kudu Local Government Area in Kano State, Nigeria. Understanding the levels of trace metals in these water sources is crucial for assessing potential health risks and ensuring safe drinking water for the local population. The samples undergo evaporation to dryness and are then pre-concentrated with 0.5 M nitric acid. The metals were analyzed using an atomic absorption spectrophotometer (AAS). The study found that all samples had iron concentrations, with the highest concentration in tap water (722.976 μg/L) and the lowest in well water (36.504 μg/L). Cadmium concentrations were highest in sample B (0.114 μg/L) and lowest in sample D (0.018 μg/L), all below WHO's permissible limit of 3 μg/L. Nickel concentrations were highest in sample C (0.336 μg/L), lowest in sample A (0.384 μg/L), and not in samples B and D (0.384 μg/L). Lead concentrations were only detected in samples A and B (0.384 μg/L), all below WHO's permissible limit of 10 μg/L. Iron was high compared to the permissible level of trace metal in water, but only in sample C, among all the samples, sample C is the safest water for drinking.
Co-Authors Abdullahi Mustaph Idris Abdullahi Mustapha Idris Aminu Ado Kaugama Ansar Bilayamin Adam Ansar Bilyamin Ansar Bilyamin Adam Ansar Bilyaminu Adam Danladi Mudwa Dwanga Emmanuel Chinedu Kingsley Emmanuel Kinsley Chinedu Haladu Mahmud Muhammad Haladu Mohammad Haruna Musa Hylalibiya Ataitiya Ibrahim Sani Kabiru Bashir Ahmad Mohammed Haladu Mudwa Danladi Dwanga Muhammed Haladu Ogunwole Adeshewa Titilayo Pambani Reuben Reuben Pambani Ruslan Shamsuddeen Ruslan Shamsudden Saeed Abdullahi Shamsu Abdullahi Idris Shittu Abubakar Muhammad Shitu Muhammad Abubakar Twan Sale Mathew Usman Sabiu Usman