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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology
Ruslan Shamsuddeen
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Public Health Social Sciences

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Organocatalysis: A Revolutionary Approach in Organic Synthesis Kabiru Bashir Ahmad; Emmanuel Kinsley Chinedu; Reuben Pambani; Ansar Bilyaminu Adam; Musa Yahaya Abubakar; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3518

Abstract

Organocatalysis has emerged as a powerful tool in organic synthesis, enabling the efficient and selective formation of complex molecules. This review highlights the recent advances in organocatalysis, including the development of new catalysts, reactions, and applications. The advantages and limitations of organocatalysis are discussed, and its potential for scalability and sustainability is evaluated. The review also explores the mechanistic insights and future directions in this field, demonstrating the versatility and impact of organocatalysis in modern organic synthesis. This paradigm shift not only addresses the pressing environmental challenges but also paves the way for more innovative and economically viable synthetic strategies. As a result, organic synthesis is poised to play a crucial role in advancing pharmaceuticals, materials science, and agrochemicals, driving forward a more sustainable and resilient chemical industry.
The Impact of Water Quality on Human Nutrition: A Review of the Relationship between Water Intake and Nutrient Absorption Musa Yahaya Abubakar; Mohammed Haladu; Pambani Reuben; Twan Sale Mathew; Ansar Bilyaminu Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3544

Abstract

Water quality is intrinsically linked to human health, and ensuring access to clean and safe water is a fundamental public health goal, Water is essential to human health as it assists with nutrient delivery and digestion. The chemical, physical, and microbiological qualities of water have a substantial impact on the gastrointestinal tract's ability to absorb nutrients. Heavy metals, insecticides, and microbial infections are examples of contaminants that can hinder digestive processes, resulting in nutrient shortages and absorption. Pure, high-grade water can improve the absorption of nutrients and the effectiveness of digestion. This review examines the connection between nutrient absorption and water quality, with a particular emphasis on the effects of water pollution on human health. According to the review, nutrient absorption is greatly impacted by water quality, particularly in groups that are more sensitive. It emphasizes how crucial it is to monitor and control water quality better in order to provide the best possible nutrition and health results. This review synthesizes current research to elucidate the mechanisms through which water quality impacts nutrient absorption and overall nutritional status. It also highlights the public health implications, particularly in areas with inadequate access to clean water, and suggests interventions to improve water quality and support optimal health outcomes. water quality has a significant impact on human nutrition by influencing nutrient absorption, overall health, and hydration. Contaminants in water can interfere with nutrient absorption and cause a range of health issues, ultimately affecting the availability of essential nutrients in the body. Therefore, addressing water quality issues is crucial for promoting optimal nutrition and improving human health. The findings underscore the importance of ensuring access to clean drinking water as a fundamental component of nutritional health and public well-being.
Natural Products as Leads for Neglected Trophical Diseases (NTDs) Treatment; A Chemical and Biological - Review Twan Sale Mathew; Emmanuel Kinsley Chinedu; Muhammed Haladu; Musa Yahaya Abubakar; Ansar Bilayamin Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3735

Abstract

Natural compounds are mostly found in medicinal plants that are used to treat various ailments. They are distinguished by their structural complexity and diversity, which span a wide chemical universe and present both benefits and shortcomings to the process of discovering novel drugs. Neglected tropical diseases (NTDs) are common tropical diseases that impact over one billion people globally. Numerous pathogens, such as bacteria, fungi, viruses, parasites, and poisons, are responsible for them. Natural products have always been important in the search for new drugs to treat differents diseases including NTDs. The purpose of this chapter is to provide an update on the evaluation of both the chemical and biological properties of natural compounds that have been extracted and identified from plant sources, and may be utilized as viable candidates for the development of new drugs treat NTDs with lower incidence such as: Buruli ulcer, dracunculiasis, echinococcosis, food-borne trematodiases, leprosy, lymphatic filariasis, parasitics, schistosomiasis, soil-transmitted helminthiases, taeniasis/cysticercosis, trachoma and yaws. This chapter also intends to make a critical review on the chemical analysis of natural products’ structure and classification, biological evaluation of natural products’ antiparasitic, anti-inflammatory and immunomodulatory activities. In conclusion, Natural products continue to be a key source of fresh ideas for treating NTDs. Their distinct methods of action and variety of chemicals offer potential for the development of new treatments.
Heavy Metals Tolerant Bacteria Detection from Selected Scrap Metal Dump Site: A Review Haladu Mahmud Muhammad; Mukhtar Umar Nasir; Ansar Bilyaminu Adam; Ruslan Shamsuddeen
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 1 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i1.3468

Abstract

This study aimed to detect heavy-tolerant bacteria from selected scrap metal dump sites. Heavy metals are the major setbacks to many forms of life and their presence in the ecosystem rapid increase of heavy metal contamination is due to anthropogenic activities, rampant scrap metal waste disposal, and other industrial wastes. Bacteria were found to be among the many microorganisms that can tolerate many heavy metals and can as well reduce their toxicity or even convert them to useful resources. This study aims to detect the heavy metal concentration and the bacterial species capable of tolerating the identified heavy metals from selected metal dump sites. The heavy metals content of the soil samples was analyzed using Atomic Absorption Spectrophotometry (AAS). Standard methods of enrichment culture and colony count were used to isolate a total of 12 bacterial species. Using 16S rRNA gene sequence-based molecular systematics, the 12 isolates were identified and grouped into one genus (Bacillus). It was observed from the results that the heavy metals (Pb, Zn, Cu, Cd, and Cr) concentrations found to be high above the WHO permissible limits (Copper-2.0, Zinc-3.0, Lead-0.4, Chromium-0.05, and Cadmium-0.03). Therefore, the bacterial isolates capable of surviving at such levels of heavy metals could have a potential application in the bioremediation and bioleaching of heavy metal contaminants.
Challenges and Opportunities in Repurposing Natural Products for the Treatment of Neglected Trophical Diseases: A Review of Scaffold Optimization Strategies Musa Yahaya Abubakar; Twan Sale Mathew; Ruslan Shamsuddeen; Saeed Abdullahi; Ansar Bilyamin; Emmanuel Kinsley Chinedu
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3725

Abstract

Neglected Tropical Diseases (NTDs) are serious health issues that affect the entire world, especially in low-income tropical and subtropical areas, yet they do not get enough facilities. Natural items have great potential for treating NTD because of their varied chemical scaffolds. Nevertheless, there are a number of difficulties in optimizing these scaffolds for drug development. Attempts at synthesis and modification are complicated by the structural complexity of natural compounds. Economic and regulatory hurdles also obstruct advancement. Despite these difficulties, there are plenty of chances. Natural products are a significant source of structural variety that makes them ideal for drug discovery. developments in biotechnology and synthetic biology. Sustainable production is improved via biotechnology. Targeted optimization is made easier by advances in computer power and molecular understanding. Research collaborations can expedite the process of discovery and development. Finding efficient scaffolds can be done quickly by looking for NTD activity in already-existing natural product libraries. By tackling these issues scientifically and cooperatively, we can develop novel, practical, and affordable treatments for non-traumatic disabilities (NTDs), which will eventually improve the health of impacted communities.
Environmental Remediation Using Nanoparticles: A Review Ruslan Shamsuddeen; Ansar Bilyaminu Adam; Twan Sale Mathew; Musa Yahaya Abubakar
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3622

Abstract

The use of nanoparticles for environmental remediation has gained significant attention in recentyears due to their unique properties and potential to revolutionize the field. This review providesa comprehensive overview of the current state of knowledge on the application of nanoparticlesfor environmental remediation, including the removal of heavy metals, pesticides, industrialeffluents, and other pollutants from water, soil, and air. The review discusses the various types ofnanoparticles used, including metal, oxide, and carbon-based nanoparticles, and theirmechanisms of action. The advantages and limitations of nanoparticle-based remediationtechnologies are also eval_uated, and future research directions are identified. The reviewhighlights the potential of nanoparticles to enhance the efficiency, sustainability, and cost-effectiveness of environmental remediation processes, and underscores the need for furtherresearch to fully realize their potential.
Effect of Particle Size and Fiber Loading on Some Properties of Sugarcane Bagasse Reinforced Unsaturated Polyester Composites Ruslan Shamsuddeen; Haruna Musa; Twan Sale Mathew; Musa Yahaya Abubakar; Ansar Bilyaminu Adam
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3718

Abstract

In recent times, the use of sugarcane bagasse as reinforcement in plastic composites has been receiving greater scientific attention due to its abundance, light weight and good mechanical properties. This research has investigated the mechanical properties of the composite by hardness strength, impact strength, chemical resistant test, and water absorption test with different particle size and loading of sugarcane bagasse (SCB) as reinforcement in unsaturated polyester resin (UPR) composite. Bagasse fiber was treated with sodium hydroxide (10%), potassium permanganate (5%), hydrogen peroxide (5%) to enhance better adhesion between the fiber and the matrix. Sugarcane bagasse reinforced unsaturated polyester resin composite was prepared using the compression molding technique, the mold was undergoing a curing process for 5 minutes with 1300 c and 2.5Mpa of pressure. The result of the mechanical properties were eval_uated, the mechanical properties (flexural strength, hardness strength) increases with increase in bagasse content while the impact strength increase and then decreases, the maximum mechanical properties was obtained from the composite made of 400µ and 25 wt% fiber loading compared with the control sample. The improvement in the mechanical properties is attributed to the extent of good interaction between the fiber and the matrix. The composite show increase in water absorption with increasing fiber loading and increasing number of days up to when the samples reaches their saturation when no water absorption was observed, 25wt% of 710µ has the highest absorption and this is due to its bigger particle size and fiber loading. The mechanical and physical properties shows that the composite has potential applications in structural materials such as particle board, fiber board, library shelf’s, partitioning panels, ceiling boards.
Co-Authors Ansar Bilayamin Adam Ansar Bilyamin Ansar Bilyaminu Adam Emmanuel Kinsley Chinedu Haladu Mahmud Muhammad Haruna Musa Kabiru Bashir Ahmad Mohammed Haladu Muhammed Haladu Mukhtar Umar Nasir Musa Yahaya Abubakar Pambani Reuben Reuben Pambani Saeed Abdullahi Twan Sale Mathew