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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology
Twan Sale Mathew
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Public Health Social Sciences

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The Impact of Water Quality on Human Nutrition: A Review of the Relationship between Water Intake and Nutrient Absorption Musa Yahaya Abubakar; Mohammed Haladu; Pambani Reuben; Twan Sale Mathew; Ansar Bilyaminu Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3544

Abstract

Water quality is intrinsically linked to human health, and ensuring access to clean and safe water is a fundamental public health goal, Water is essential to human health as it assists with nutrient delivery and digestion. The chemical, physical, and microbiological qualities of water have a substantial impact on the gastrointestinal tract's ability to absorb nutrients. Heavy metals, insecticides, and microbial infections are examples of contaminants that can hinder digestive processes, resulting in nutrient shortages and absorption. Pure, high-grade water can improve the absorption of nutrients and the effectiveness of digestion. This review examines the connection between nutrient absorption and water quality, with a particular emphasis on the effects of water pollution on human health. According to the review, nutrient absorption is greatly impacted by water quality, particularly in groups that are more sensitive. It emphasizes how crucial it is to monitor and control water quality better in order to provide the best possible nutrition and health results. This review synthesizes current research to elucidate the mechanisms through which water quality impacts nutrient absorption and overall nutritional status. It also highlights the public health implications, particularly in areas with inadequate access to clean water, and suggests interventions to improve water quality and support optimal health outcomes. water quality has a significant impact on human nutrition by influencing nutrient absorption, overall health, and hydration. Contaminants in water can interfere with nutrient absorption and cause a range of health issues, ultimately affecting the availability of essential nutrients in the body. Therefore, addressing water quality issues is crucial for promoting optimal nutrition and improving human health. The findings underscore the importance of ensuring access to clean drinking water as a fundamental component of nutritional health and public well-being.
Natural Products as Leads for Neglected Trophical Diseases (NTDs) Treatment; A Chemical and Biological - Review Twan Sale Mathew; Emmanuel Kinsley Chinedu; Muhammed Haladu; Musa Yahaya Abubakar; Ansar Bilayamin Adam; Ruslan Shamsuddeen
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3735

Abstract

Natural compounds are mostly found in medicinal plants that are used to treat various ailments. They are distinguished by their structural complexity and diversity, which span a wide chemical universe and present both benefits and shortcomings to the process of discovering novel drugs. Neglected tropical diseases (NTDs) are common tropical diseases that impact over one billion people globally. Numerous pathogens, such as bacteria, fungi, viruses, parasites, and poisons, are responsible for them. Natural products have always been important in the search for new drugs to treat differents diseases including NTDs. The purpose of this chapter is to provide an update on the evaluation of both the chemical and biological properties of natural compounds that have been extracted and identified from plant sources, and may be utilized as viable candidates for the development of new drugs treat NTDs with lower incidence such as: Buruli ulcer, dracunculiasis, echinococcosis, food-borne trematodiases, leprosy, lymphatic filariasis, parasitics, schistosomiasis, soil-transmitted helminthiases, taeniasis/cysticercosis, trachoma and yaws. This chapter also intends to make a critical review on the chemical analysis of natural products’ structure and classification, biological evaluation of natural products’ antiparasitic, anti-inflammatory and immunomodulatory activities. In conclusion, Natural products continue to be a key source of fresh ideas for treating NTDs. Their distinct methods of action and variety of chemicals offer potential for the development of new treatments.
Physicochemical Parameters of Borehole Water, Tap Water and Well Water from Dawakin Kudu Local Government Area of Kano State, Nigeria Abdullahi Mustaph Idris; Musa Yahaya Abubakar; Haladu Mohammad; Shittu Abubakar Muhammad; Twan Sale Mathew; Ansar Bilyamin Adam
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 1 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i1.3737

Abstract

Quality water is very important for maintenance of healthy environment, to determine the safety of the water consumed in the environment, pH, Turbidity, electrical conductivity, Alkalinity and hardness of water samples borehole, tap and well were analyzed. The result of the study showed that the pH of the water samples were found to be 6.3borehole, 6.7 tap and 6.8 well water, Turbidity were found to be 0 borehole, 1 tap and 0(NTU) well water, while conductivity were found to be 401 borehole, 635 tap and 556(µS/cm), well water and Hardness were found to be 172borehole, 68 tap and 88 mg/ml well water . The physicochemical analysis carried out the pH of the water were found to be from 6.3 to 6.8 only two of the samples are below the ranges laid down by W.H.O which are sample A and D and in conductivity also two of the samples are above the limit which are sample B and C and for the total hardness all are below the permissible limit by the standard (W.H.O).
Exploring the Chemical Properties and Mechanisms of Herbal Remedies in Moringa, and Ginger in Managing Chronic Diseases: Review Musa Yahaya Abubakar; Twan Sale Mathew; Ansar Bilyaminu Adam; Kabiru Bashir Ahmad; Hylalibiya Ataitiya; Aminu Ado Kaugama
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 1 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i1.3472

Abstract

Herbal remedies have been used for centuries to treat various ailments. Natural products, derived from plants, animals, and microorganisms, have been used for centuries as a source of medicinal compounds in traditional and modern herbal remedies. Understanding the chemical properties and mechanisms of action of these remedies is crucial for their effective and safe application in managing chronic diseases. This review explores the effectiveness of herbal remedies in managing chronic diseases such as diabetes, cardiovascular diseases, and autoimmune disorders. It emphasizes the need for a balanced approach combining herbal and conventional medicine, reducing healthcare costs and improving patient outcomes. The review includes 10 studies investigating the efficacy of herbal remedies in managing chronic diseases in Moringa and Ginger. Moringa, a valuable plant in traditional and modern medicine, has diverse therapeutic effects, making it beneficial for managing chronic diseases. Ginger, a powerful herbal remedy with bioactive compounds like gingerols, shogaols, zingerone, and paradols, is also considered a powerful natural treatment due to its antioxidant, anti-inflammatory, antimicrobial, antiemetic, and anticancer activities. Understanding the chemical properties and mechanisms of action of these remedies can help develop effective treatments for chronic diseases and enhance their integration into modern medicine.
The Devastating Impact of Heavy Metal Contamination on Plant Growth and Development: Unveiling Phytotoxicity and Exploring Remediation Strategies Hylalibiya Ataitiya; Kabiru Bashir Ahmad; Aminu Ado Kaugama; Shamsu Abdullahi Idris; Ansar Bilyaminu Adam; Musa Yahaya Abubakar; Twan Sale Mathew
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3495

Abstract

Heavy metal contamination poses a significant threat to plant growth and development, leading to reduced crop yields, impaired ecosystem functioning, and potential human health risks. This review provides a comprehensive overview of the phytotoxic effects of heavy metals on plant species, highlighting the mechanisms of uptake, transport, and accumulation. We explore the devastating impacts on plant morphology, physiology, and biochemistry, including altered root architecture, reduced photosynthesis, and impaired reproductive development. This review highlights the urgent need for effective remediation approaches to mitigate the phytotoxic effects of heavy metals and ensure sustainable ecosystem functioning. We identify knowledge gaps and future research directions, emphasizing the importance of interdisciplinary collaboration to address this critical environmental issue.
Phytochemical Analysis of Carrot, Red Pepper, Spinach and Lettuce Cultivated at Ajiwa, Batagarawa, Lambun Sarki and Dankama Vegetable Farms, Katsina State, Nigeria Sabiru Dahiru; Yazid Salele; Twan Sale Mathew; Ansar Bilyaminu Adam
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3724

Abstract

Katsina state for long has been a major aggregation centre for cash crops including vegetables due to the availability of suitable land and adequacy of water supply, phytochemical analysis of vegitables cultivated at , batagarawa, lambun sarki and dankama vegetable farms were investigated, This study investigates the metabolites present in sample, the presence of tannins, flavonoids and saponins were tested. The results of the study showed the presence flavonoids, and tannins in lettuce, red pepper showed the presence only flavonoids, carrot showed the presence flavonoids, saponin and tannins, spinach showed the presence of tannin and saponin, while lettuce showed the presence Tannins, Saponins, Flavonoids. Therefore, lettuce, spinach and carrot could serve as potential source of natural antioxidants, red pepper could serve as a source of both antioxidant and anti-inflammatory.
Challenges and Opportunities in Repurposing Natural Products for the Treatment of Neglected Trophical Diseases: A Review of Scaffold Optimization Strategies Musa Yahaya Abubakar; Twan Sale Mathew; Ruslan Shamsuddeen; Saeed Abdullahi; Ansar Bilyamin; Emmanuel Kinsley Chinedu
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3725

Abstract

Neglected Tropical Diseases (NTDs) are serious health issues that affect the entire world, especially in low-income tropical and subtropical areas, yet they do not get enough facilities. Natural items have great potential for treating NTD because of their varied chemical scaffolds. Nevertheless, there are a number of difficulties in optimizing these scaffolds for drug development. Attempts at synthesis and modification are complicated by the structural complexity of natural compounds. Economic and regulatory hurdles also obstruct advancement. Despite these difficulties, there are plenty of chances. Natural products are a significant source of structural variety that makes them ideal for drug discovery. developments in biotechnology and synthetic biology. Sustainable production is improved via biotechnology. Targeted optimization is made easier by advances in computer power and molecular understanding. Research collaborations can expedite the process of discovery and development. Finding efficient scaffolds can be done quickly by looking for NTD activity in already-existing natural product libraries. By tackling these issues scientifically and cooperatively, we can develop novel, practical, and affordable treatments for non-traumatic disabilities (NTDs), which will eventually improve the health of impacted communities.
Determination of Trace Metals in Borehole, Tap, and Well Water from Dawakin Kudu Local Government Area of Kano State, Nigeria Abdullahi Mustapha Idris; Shittu Abubakar Muhammad; Twan Sale Mathew; Musa Yahaya Abubakar; Ibrahim Sani; Ansar Bilyaminu Adam
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3567

Abstract

This study investigates the concentration of trace metals in borehole, tap, and well water samples from Dawakin Kudu Local Government Area in Kano State, Nigeria. Understanding the levels of trace metals in these water sources is crucial for assessing potential health risks and ensuring safe drinking water for the local population. The samples undergo evaporation to dryness and are then pre-concentrated with 0.5 M nitric acid. The metals were analyzed using an atomic absorption spectrophotometer (AAS). The study found that all samples had iron concentrations, with the highest concentration in tap water (722.976 μg/L) and the lowest in well water (36.504 μg/L). Cadmium concentrations were highest in sample B (0.114 μg/L) and lowest in sample D (0.018 μg/L), all below WHO's permissible limit of 3 μg/L. Nickel concentrations were highest in sample C (0.336 μg/L), lowest in sample A (0.384 μg/L), and not in samples B and D (0.384 μg/L). Lead concentrations were only detected in samples A and B (0.384 μg/L), all below WHO's permissible limit of 10 μg/L. Iron was high compared to the permissible level of trace metal in water, but only in sample C, among all the samples, sample C is the safest water for drinking.
Heavy Metal Pollution in Aquatic Ecosystems: A Review of Toxic Impacts and Remediation Strategies Musa Yahaya Abubakar; Kabiru Bashir Ahmad; Twan Sale Mathew; Ruslan Shamsudden; Haladu Mahmud Muhammad; Mohammed Haladu; Ansar Bilyaminu Adam
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3621

Abstract

Heavy metals contamination in aquatic ecosystems is a critical environmental issue with far-reaching implications for ecological health and human safety, Heavy metal pollution in aquatic ecosystems is a pressing environmental concern, posing significant risks to aquatic life and human health. This review summarizes the toxic effects of heavy metals (HMs) on aquatic organisms, ecosystems, and human consumers. The study explores the sources, fate, and transport of HMs in aquatic environments, highlighting their bioaccumulation, biomagnification, and ecological impacts. Remediation strategies, including phytoextraction, bioaugmentation, and chemical treatment, are critically eval_uated. Emerging technologies, such as Nano remediation and bioremediation, offer promising solutions. The study showed heavy metal pollution in aquatic ecosystems is a significant environmental challenge that requires coordinated efforts from governments, industries, and communities to mitigate its impacts and protect water quality and aquatic life. By addressing the sources and effects of heavy metals in aquatic habitats, we can mitigate their impact on the environment and human health, ensuring the sustainability of these vital ecosystems.
Environmental Remediation Using Nanoparticles: A Review Ruslan Shamsuddeen; Ansar Bilyaminu Adam; Twan Sale Mathew; Musa Yahaya Abubakar
Kwaghe International Journal of Sciences and Technology Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v1i1.3622

Abstract

The use of nanoparticles for environmental remediation has gained significant attention in recentyears due to their unique properties and potential to revolutionize the field. This review providesa comprehensive overview of the current state of knowledge on the application of nanoparticlesfor environmental remediation, including the removal of heavy metals, pesticides, industrialeffluents, and other pollutants from water, soil, and air. The review discusses the various types ofnanoparticles used, including metal, oxide, and carbon-based nanoparticles, and theirmechanisms of action. The advantages and limitations of nanoparticle-based remediationtechnologies are also eval_uated, and future research directions are identified. The reviewhighlights the potential of nanoparticles to enhance the efficiency, sustainability, and cost-effectiveness of environmental remediation processes, and underscores the need for furtherresearch to fully realize their potential.
Co-Authors Abdullahi Mustaph Idris Abdullahi Mustapha Idris Aminu Ado Kaugama Ansar Bilayamin Adam Ansar Bilyamin Ansar Bilyamin Adam Ansar Bilyaminu Adam Emmanuel Kinsley Chinedu Haladu Mahmud Muhammad Haladu Mohammad Haruna Musa Hylalibiya Ataitiya Ibrahim Sani Kabiru Bashir Ahmad Mohammed Haladu Muhammed Haladu Musa Yahaya Abubakar Pambani Reuben Ruslan Shamsuddeen Ruslan Shamsudden Sabiru Dahiru Saeed Abdullahi Shamsu Abdullahi Idris Shittu Abubakar Muhammad Yazid Salele