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All Journal Health Research Journal of Indonesia Jurnal Edukasi Pengabdian Masyarakat: EDUABDIMAS Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Dita Apriana Dwi Astuti
Universitas Kadiri
Religion Humanities Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Jumlah Neutrofil sebagai Penanda Inflamasi pada Diabetes Melitus Tipe 2 dengan dan tanpa Ulkus Aprilia Anjarwati; Elfred Rinaldo Kasimo; Dita Apriana Dwi Astuti
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 2 (2026): Juli: Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i2.10194

Abstract

Type 2 diabetes mellitus causes chronic hyperglycemia, systemic inflammation, and immune dysfunction, which increase the risk of diabetic foot ulcers, amputation, and mortality. This study is urgent because the dominance of elevated neutrophil counts in T2DM patients with ulcers reflects an active inflammatory response that may worsen wound healing, while neutrophil testing is widely available in clinical pathology laboratories. The literature highlights the role of inflammation, cytokines, NLR, and complex biomarkers in diabetic complications; however, these indicators are often costly, less applicable in regional healthcare settings, and rarely compare ulcerated and non-ulcerated T2DM patients directly. This study addresses this gap by proposing absolute neutrophil count as a simple, quantitative, and categorical inflammatory indicator. The objective was to analyze differences in neutrophil counts between T2DM patients with and without ulcers at RSU Daha Husada Kediri using a comparative descriptive quantitative design involving 20 patients. The results showed that 80% of ulcerated T2DM patients had elevated neutrophil levels compared with 10% in the non-ulcer group, with a significantly higher mean neutrophil count (9.19 ± 2.56 vs 4.80 ± 1.32 ×10³/µL; p = 0.00012). In conclusion, increased neutrophil counts significantly distinguish the inflammatory status of T2DM patients with ulcers and represent a practical clinical marker for early screening of diabetic foot ulcer complications in regional hospitals.
EDUKASI OBESITAS SEBAGAI UPAYA PREVENTIF PENYAKIT METABOLIK PADA USIA PRODUKTIF DI DESA POJOK KEDIRI Dita Apriana Dwi Astuti; Aprilia Anjarwati; Rochmad Krissanjaya; Saiful Muttaqin; Elfred Rinaldo Kasimo
Jurnal Edukasi Pengabdian Masyarakat Vol 5 No 3 (2026): JULI 2026
Publisher : FIP UNIRA MALANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36636/eduabdimas.v5i3.9648

Abstract

Obesity is one of the major risk factors for metabolic diseases such as type 2 diabetes mellitus, hypertension, dyslipidemia, and cardiovascular disease, particularly among the productive-age population. The increasing prevalence of obesity in the community indicates the need for promotive and preventive efforts through health education. This Community Service Program aimed to improve the knowledge and awareness of productive-age individuals regarding obesity as a risk factor for metabolic diseases and to encourage the adoption of healthy lifestyles in Pojok Village, Kediri. The program was conducted through health counseling, interactive discussions, and anthropometric assessments, including measurements of body weight, height, and Body Mass Index (BMI) calculation among 47 participants. The results showed that the majority of participants were female (72.3%). Based on BMI classification, 31 participants (65.96%) were categorized as obese, 11 participants (23.40%) as overweight, and only 5 participants (10.64%) had normal BMI status. These findings indicate a high risk of metabolic disorders among the productive-age population in the intervention area. The educational activities received positive responses and improved participants’ understanding of the importance of balanced nutrition, regular physical activity, and routine body weight monitoring. In conclusion, obesity education through the Community Service Program was effective as an initial preventive strategy to improve public health literacy and reduce the risk of metabolic diseases.
Perbandingan Natrium Serum Pre dan Post Hemodialisis pada Pasien Gagal Ginjal Kronis di RSUD Kotamobagu saiful muttaqin; Rochmad Krissanjaya; Dita Apriana Dwi Astuti; Alfittrisno Munir; Syntia Tanu Juwita
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1281

Abstract

Penyakit ginjal kronis (PGK) merupakan gangguan progresif dan irreversibel yang menyebabkan penurunan fungsi ginjal dalam menjaga keseimbangan cairan dan elektrolit, termasuk natrium serum. Ketidakseimbangan natrium pada pasien PGK yang menjalani hemodialisis dapat meningkatkan risiko komplikasi, sehingga pemantauan kadar natrium perlu dilakukan secara rutin. Penelitian ini bertujuan untuk menganalisis perbedaan kadar natrium serum sebelum dan sesudah hemodialisis pada pasien gagal ginjal kronis di RSUD Kotamobagu. Penelitian ini menggunakan desain deskriptif kuantitatif dengan pendekatan cross-sectional. Sampel berjumlah 29 pasien yang dipilih menggunakan teknik total sampling. Pemeriksaan natrium serum dilakukan dengan metode Ion Selective Electrode (ISE) pada autoanalyzer, kemudian data dianalisis menggunakan uji Paired Sample T-Test. Hasil penelitian menunjukkan bahwa sebelum hemodialisis, 89,66% pasien memiliki kadar natrium normal dan 10,34% rendah. Setelah hemodialisis, kadar natrium normal meningkat menjadi 93,10%, sedangkan kadar rendah menurun menjadi 6,90%. Hasil uji statistik menunjukkan nilai p=0,277, sehingga tidak terdapat perbedaan bermakna antara kadar natrium serum sebelum dan sesudah hemodialisis. Dengan demikian, hemodialisis belum menunjukkan perubahan signifikan terhadap kadar natrium serum, meskipun terjadi perbaikan proporsi kadar natrium normal.
Co-Authors Alfittrisno Munir Aprilia Anjarwati Elfred Rinaldo Kasimo Rochmad Krissanjaya Saiful Muttaqin Syntia Tanu Juwita