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All Journal Pharmademica: Jurnal Kefarmasian dan Gizi Sehat Rakyat: Jurnal Kesehatan Masyarakat Jurnal Kesehatan Amanah Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi Kolaborasi: Jurnal Hasil Kegiatan Kolaborasi Pengabdian Masyarakat
Yani Pratiwi
Institut Ilmu Kesehatan Pelamonia
Agriculture, Biological Sciences & Forestry Humanities Chemistry Dentistry Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Analisis Sistem Rantai Pasok Farmasi: Evaluasi Kepatuhan Prosedural Penerimaan Logistik dan Implikasinya terhadap Patient Safety di Apotek Kota Makassar Irfan Kurniawan; Asyari Al Hutama; Salwah Suardi; Yani Pratiwi
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i1.6735

Abstract

The reception of health logistics represents a critical initial stage that determines the quality and safety of pharmaceutical preparations, medical devices, and medical consumables prior to their use in patient care. This study aims to analyze the implementation of health logistics reception procedures at PSJ, PT, and PP Pharmacies in Makassar City based on the Pharmaceutical Service Standards outlined in Ministry of Health Regulation Number 73 of 2016. An observational design with a descriptive quantitative and evaluative approach was employed through direct observation and interviews with the Pharmacist in Charge and relevant personnel. Data were collected using a checklist comprising nine reception indicators and analyzed using percentage calculations based on the Guttman scale. The findings show that all pharmacies consistently and comprehensively executed every required procedure. Each facility achieved the maximum evaluation score of nine out of nine, reflecting a one hundred percent compliance rate categorized as very good. All stages, including physical product inspection, document verification, batch number and expiration date checking, management of discrepancies through return procedures, and administrative validation, were conducted in accordance with regulatory requirements. These results indicate that the managerial aspects of health logistics reception across the three pharmacies are well structured and accurate, ensuring the quality and safety of products prior to patient use. The study recommends regular internal audits and the development of logistics management innovations to maintain and enhance reception performance in subsequent periods.
Cost Effectivie Analysis (CEA) Pengobatan Tunggal dan Kombinasi pada Pasien Tuberkulosis Paru di RSUD dr. La Palaloi Kabupaten Maros Ira Widya Sari; Yani Pratiwi; Irfan Kurniawan; A.Aulia Salsabila
Jurnal Kesehatan Amanah Vol. 9 No. 2 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i2.976

Abstract

TB treatment requires long-term therapy using anti-tuberculosis drugs (OTAs), either singly or in combination. The use of combination therapy is considered more effective in preventing drug resistance and increasing treatment success. However, the choice of therapy method is also influenced by economic considerations, considering the continuing increase in health care costs. Therefore, a pharmacoeconomic analysis is needed, specifically a Cost Effectiveness Analysis (CEA) to compare the costs and effectiveness of two treatment alternatives, namely single OAT therapy and combination therapy. Cost Effectiveness Analysis (CEA) is a type of pharmacoeconomic analysis in which all costs are compared with the effects of two or more treatment options. Single OAT treatment is a medical action undertaken by tuberculosis patients, while combination treatment is a treatment method consisting of two or more drugs or treatment techniques used simultaneously to increase treatment effectiveness, reduce the risk of resistance, or improve clinical outcomes. The research method is a descriptive non-experimental, the data studied are retrospective using secondary data from patient medical records. The results showed that treatment of pulmonary tuberculosis using combination therapy (rifampicin and isoniazid) is more cost-effective with an ACER value of Rp132. 182 compared to single therapy (ethambutol) with an ACER value of Rp. 170,536 and an ICER value of combination and single therapy of Rp. 119,857.
Standardisasi Simplisia dan Ekstrak Daun Jambu Mete (Anacardium occidentale L.) dari Kabupaten Gowa Sulawesi Selatan Asyari Al Hutama Azis; Yani Pratiwi; Irva Maulidiyah Putri
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 5 No 2 (2026): Oktober - Maret
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v5i2.118

Abstract

Cashew leaves (Anacardium occidentale L.) contain secondary metabolite compounds such as flavonoids, tannins, polyphenols, alkaloids, saponins, and phenolics, which exhibit pharmacological activities, including antioxidant and antibacterial properties. Traditionally, cashew leaves are used by the people of Gowa Regency to treat diabetes mellitus, oral inflammation, burns, muscle aches, and skin infections such as acne and boils. This study aims to evaluate the quality of cashew leaf raw materials from Gowa Regency based on specific parameters, namely water-soluble and ethanol-soluble extract content in the simplicia. Additionally, nonspecific parameters were evaluated, including drying loss, total ash content, and acid-insoluble ash content in the simplicia, as well as water content, total ash content, and acid-insoluble ash content in the extract, according to the Indonesian Herbal Pharmacopoeia Edition II (2017). Extraction was performed using the maceration method with 70% ethanol, yielding 21.2%. The results showed that the simplicia contained 13.46% water-soluble extract, 18.23% ethanol-soluble extract, 9.93% drying loss, 3.03% total ash, and 0.71% acid-insoluble ash. Meanwhile, the extract showed a water content of 18.26%, total ash of 0.89%, and acid-insoluble ash of 0.39%. Both the simplicia and extract of cashew leaves from Gowa Regency met the quality requirements of the Indonesian Herbal Pharmacopoeia Edition II (2017) and were categorized as high quality.
Implementasi Manajemen Farmasi di Apotek: Analisis Kesesuaian Penyimpanan Obat Berdasarkan Standar Pelayanan Kefarmasian Irfan Kurniawan; Yani Pratiwi; Asyari Al Hutama Azis
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.5707

Abstract

Healthcare facilities play an essential role, not only as a place for pharmacists to carry out pharmacy practice but also in ensuring the quality of medicines provided to the community. Therefore, the aspect of drug storage is a crucial factor that requires careful attention. If not managed in accordance with established standards, it may decrease drug effectiveness, accelerate deterioration, cause dispensing errors, and result in undetected drugs that are nearing or have already passed their expiration date. The objective of this study was to identify drug storage management in APP, APT, and APSJ in Makassar City and to analyze the level of conformity of these storage systems with Pharmaceutical Service Standards No. 73 of 2016. Data were collected through direct observation using a checklist and interviews. This study employed an observational method with a descriptive quantitative and evaluative approach, which involved observing ongoing activities and comparing them with the regulations related to pharmaceutical service standards, particularly regarding drug storage management. The collected data were analyzed using descriptive assessment categories, where scores of 81–100% were classified as “very good,” 61–80% as “good,” 41–60% as “fair,” 21–40% as “poor,” and 0–20% as “very poor.” Based on the observations, the drug storage systems in APP, APT, and APSJ in Makassar City achieved scores of 90.48%, 90.91%, and 90.91%, respectively. These results fall into the “very good” category, indicating compliance with the Technical Guidelines for Pharmaceutical Services issued in 2019.
Pemanfaatan Tanaman Herbal Lokal sebagai Minuman Fungsional Antihipertensi dalam Mendukung Kesehatan Masyarakat Desa Ko'mara, Kabupaten Takalar Yani Pratiwi; Hijrawati Ayu Wardani; Mashud Mashud
Kolaborasi : Jurnal Hasil Kegiatan Kolaborasi Pengabdian Masyarakat Vol. 4 No. 3 (2026): September: Kolaborasi : Jurnal Hasil Kegiatan Kolaborasi Pengabdian
Publisher : Asosiasi Riset Ilmu Matematika dan Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/kolaborasi.v4i3.1070

Abstract

Hypertension is a non-communicable disease with a high prevalence that contributes significantly to the risk of cardiovascular diseases. This problem is also found in rural communities due to limited access to healthcare services, low routine blood pressure monitoring, and insufficient knowledge regarding hypertension prevention. Indonesia has abundant local herbal resources containing bioactive compounds with potential antihypertensive effects. However, their utilization remains limited due to inadequate knowledge regarding plant identification, processing methods, and safety aspects.This community service program aims to improve the knowledge and skills of the people in Ko'mara Village, Takalar Regency, in utilizing local herbal plants as antihypertensive functional beverages. The activities include education on hypertension and rational herbal utilization, training on herbal processing into functional beverage products, and guidance on safe usage. This program is expected to increase community awareness in preventing hypertension while optimizing local resources into value-added health products. Through a pharmaceutical science-based and community empowerment approach, this activity is expected to support sustainable improvement of public health and community independence.
Evaluasi Aktivitas Antiinflamasi Ekstrak Etanol Daun Sirih Merah (Piper crocatum) dan Daun Sirih Cina (Peperomia pellucida L.) pada Model Edema Kaki Mencit (Mus musculus) yang Diinduksi KaragenanEvaluasi Aktivitas Antiinflamasi Ekstrak Etanol Daun Sirih Merah (Piper crocatum) dan Daun Sirih Cina (Peperomia pellucida L.) pada Model Edema Kaki Mencit (Mus musculus) yang Diinduksi Karagenan Yani Pratiwi; Fitri Suneth; Sitidhani Zidal Ilmi; Asyari Al Hutama Azis; Mashud Mashud
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 4 No. 3 (2026): Agustus: Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v4i3.1222

Abstract

Inflammation is a physiological defense mechanism of the body in response to various pathological stimuli, including tissue injury, infection, and exposure to foreign substances. This process is characterized by clinical manifestations such as edema, pain, redness, and increased local tissue temperature. The long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) may cause several adverse effects, thereby encouraging the exploration of natural products as alternative anti-inflammatory agents. Red betel leaf (Piper crocatum) and Chinese betel leaf (Peperomia pellucida L.) are medicinal plants containing bioactive secondary metabolites, including flavonoids, alkaloids, and tannins, which are associated with anti-inflammatory activity. This study aimed to compare the anti-inflammatory activity of ethanol extracts from red betel leaf and Chinese betel leaf against carrageenan-induced paw edema in mice (Mus musculus) based on two experimental studies with comparable extraction methods, anti-inflammatory assays, and statistical analyses. The evaluated parameters included extract yield, phytochemical screening, edema measurement using a caliper and plethysmometer, and statistical analysis results. The findings showed that the ethanol extract yield of red betel leaf was 26.57%, while Chinese betel leaf extract was 24.10%. Phytochemical screening revealed that both extracts contained alkaloids, flavonoids, and tannins. Based on caliper measurements, the optimal anti-inflammatory dose of red betel leaf extract was 250 mg/kg body weight, whereas Chinese betel leaf extract showed the optimum dose at 200 mg/kg body weight. Plethysmometer measurements indicated optimal doses of 200 mg/kg body weight for red betel leaf extract and 175 mg/kg body weight for Chinese betel leaf extract. Statistical analysis demonstrated significant differences among treatment groups (p < 0.05). Both ethanol extracts exhibited potential as natural anti-inflammatory agents, although their effectiveness varied depending on dosage and edema measurement methods.
Co-Authors A.Aulia Salsabila Asyari Al Hutama Asyari Al Hutama Azis Asyari Al Hutama Azis Asyari Al Hutama Azis Fitri Suneth Hijrawati Ayu Wardani Ira Widya Sari Irfan Kurniawan Irva Maulidiyah Putri Mashud Mashud Mashud Mashud Salwah Suardi Sitidhani Zidal Ilmi