Review: Sintesis Dan Karakterisasi Nanopartikel Emas (AuNP) Serta Konjugasi AuNP Dengan DNA Dalam Aplikasi Biosensor Elektrokimia

Egista Istioka Fazrin (Padjadjaran University)
Annisa Ilma Naviardianti (Padjadjaran University)
Santhy Wyantuti (Padjadjaran University)
Shabarni Gaffar (Padjadjaran University)
Yeni Wahyuni Hartati (Padjadjaran University)

PENDIPA Journal of Science Education
Vol 4, No 2 (2020): MARCH - JUNE

The use of gold nanoparticles (AuNP) is an appropriate one in the development of biosensors because it has a unique, strong adsorption, high biocompatibility, and large surface area. AuNPs can be synthesized by various methods with the same synthesis principle by reducing Au3+ to Au. This review explains the various methods of AuNP synthesis and their characteristics, the interaction of AuNP with biomolecules including DNA, and the application of AuNP-DNA bioconjugates in biosensors. Several applications of AuNP-DNA bioconjugates as electrochemical biosensors in the past two years are proposed in this review.