Jurnal Fitofarmaka Indonesia
Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)

Postprandial Bioassay and Radical Scavenging on n-Hexane Fraction of Cordia myxa L. Leaf

Virsa Handayani (Division of Phytochemistry, Faculty of Pharmacy, Universitas Muslim Indonesia, Makassar)
Aktsar Roskiana Ahmad (Division of Pharmacognosy, Faculty of Pharmacy, Universitas Muslim Indonesia, Makassar)
Nur Rezky Khairun Nisaa (Division of Phytochemistry, Faculty of Pharmacy, Universitas Muslim Indonesia, Makassar)
La Hamidu (Department of Pharmacy, Sekolah Tinggi Ilmu Kesehatan Adila, Bandar Lampung, Indonesia)
Ahmad Najib (Division of Pharmacognosy, Faculty of Pharmacy, Universitas Muslim Indonesia, Makassar)



Article Info

Publish Date
29 Dec 2022

Abstract

Cordia myxa L. is empirically used as an antidiabetic medication. The aim of this study is to determine the in-vivo effect of Cordia myxa L. n-hexane fraction on reducing blood sugar levels and their relationship with the anti-free-radical activity assay using DPPH (1,1-diphenyl-2-Picrylhydrazyl). The n-hexane fraction of Cordia myxa L. was used as a sample in the post-prandial assay which was analyzed using the ANOVA statistical test followed by Post-Hoc test. The results showed that there were significant in the extract using a 500 mg dose. In the anti-free-radical test using DPPH (1,1-diphenyl-2-Picrylhydrazyl) at maximum wavelength of 516 nm, 16.49 µg /mL IC50 value was obtained. For comparison, Quercetin with IC50 0.13 µg/mL was used. This shows that the sample has strong anti-free radical inhibitory potential ranged from 10 µg/mL to 50 µg/mL. The data from the calculation showed that there is a correlation between its effect of lowering high blood sugar level and anti-free radical activity

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Journal Info

Abbrev

fitofarmakaindo

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Description

Jurnal Fitofarmaka Indonesia merupakan salah satu jurnal yang dikelola oleh Laboratorium Farmakognosi-Fitomikia Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Januari 2014. Jurnal Fitofarmaka Indonesia merupakan jurnal ilmiah yang terbit secara on-line dan cetakan ...